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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TUBB2A
Full Name:
Tubulin beta-2A chain
Alias:
DJ40E16.7; TUBB; TUBB2; Tubulin beta-2A; Tubulin, beta 2A; Tubulin, beta-2a
Type:
Cytoskeletal protein
Mass (Da):
49907
Number AA:
445
UniProt ID:
Q13885
International Prot ID:
IPI00013475
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0043234
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
GO:0051258
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Site 2
T33
D
E
H
G
I
D
P
T
G
S
Y
H
G
D
S
Site 3
S35
H
G
I
D
P
T
G
S
Y
H
G
D
S
D
L
Site 4
Y36
G
I
D
P
T
G
S
Y
H
G
D
S
D
L
Q
Site 5
S40
T
G
S
Y
H
G
D
S
D
L
Q
L
E
R
I
Site 6
Y50
Q
L
E
R
I
N
V
Y
Y
N
E
A
A
G
N
Site 7
Y51
L
E
R
I
N
V
Y
Y
N
E
A
A
G
N
K
Site 8
Y59
N
E
A
A
G
N
K
Y
V
P
R
A
I
L
V
Site 9
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Site 10
S75
L
E
P
G
T
M
D
S
V
R
S
G
P
F
G
Site 11
S78
G
T
M
D
S
V
R
S
G
P
F
G
Q
I
F
Site 12
S95
D
N
F
V
F
G
Q
S
G
A
G
N
N
W
A
Site 13
Y106
N
N
W
A
K
G
H
Y
T
E
G
A
E
L
V
Site 14
T107
N
W
A
K
G
H
Y
T
E
G
A
E
L
V
D
Site 15
S115
E
G
A
E
L
V
D
S
V
L
D
V
V
R
K
Site 16
S124
L
D
V
V
R
K
E
S
E
S
C
D
C
L
Q
Site 17
S126
V
V
R
K
E
S
E
S
C
D
C
L
Q
G
F
Site 18
T136
C
L
Q
G
F
Q
L
T
H
S
L
G
G
G
T
Site 19
S138
Q
G
F
Q
L
T
H
S
L
G
G
G
T
G
S
Site 20
T143
T
H
S
L
G
G
G
T
G
S
G
M
G
T
L
Site 21
S145
S
L
G
G
G
T
G
S
G
M
G
T
L
L
I
Site 22
S153
G
M
G
T
L
L
I
S
K
I
R
E
E
Y
P
Site 23
Y159
I
S
K
I
R
E
E
Y
P
D
R
I
M
N
T
Site 24
T166
Y
P
D
R
I
M
N
T
F
S
V
M
P
S
P
Site 25
S168
D
R
I
M
N
T
F
S
V
M
P
S
P
K
V
Site 26
S172
N
T
F
S
V
M
P
S
P
K
V
S
D
T
V
Site 27
S176
V
M
P
S
P
K
V
S
D
T
V
V
E
P
Y
Site 28
T178
P
S
P
K
V
S
D
T
V
V
E
P
Y
N
A
Site 29
Y183
S
D
T
V
V
E
P
Y
N
A
T
L
S
V
H
Site 30
S188
E
P
Y
N
A
T
L
S
V
H
Q
L
V
E
N
Site 31
T199
L
V
E
N
T
D
E
T
Y
S
I
D
N
E
A
Site 32
Y200
V
E
N
T
D
E
T
Y
S
I
D
N
E
A
L
Site 33
S201
E
N
T
D
E
T
Y
S
I
D
N
E
A
L
Y
Site 34
Y208
S
I
D
N
E
A
L
Y
D
I
C
F
R
T
L
Site 35
T218
C
F
R
T
L
K
L
T
T
P
T
Y
G
D
L
Site 36
T219
F
R
T
L
K
L
T
T
P
T
Y
G
D
L
N
Site 37
T221
T
L
K
L
T
T
P
T
Y
G
D
L
N
H
L
Site 38
Y222
L
K
L
T
T
P
T
Y
G
D
L
N
H
L
V
Site 39
S230
G
D
L
N
H
L
V
S
A
T
M
S
G
V
T
Site 40
S234
H
L
V
S
A
T
M
S
G
V
T
T
C
L
R
Site 41
T274
M
P
G
F
A
P
L
T
S
R
G
S
Q
Q
Y
Site 42
S275
P
G
F
A
P
L
T
S
R
G
S
Q
Q
Y
R
Site 43
S278
A
P
L
T
S
R
G
S
Q
Q
Y
R
A
L
T
Site 44
Y281
T
S
R
G
S
Q
Q
Y
R
A
L
T
V
P
E
Site 45
T285
S
Q
Q
Y
R
A
L
T
V
P
E
L
T
Q
Q
Site 46
T290
A
L
T
V
P
E
L
T
Q
Q
M
F
D
S
K
Site 47
S296
L
T
Q
Q
M
F
D
S
K
N
M
M
A
A
C
Site 48
T312
P
R
H
G
R
Y
L
T
V
A
A
I
F
R
G
Site 49
S322
A
I
F
R
G
R
M
S
M
K
E
V
D
E
Q
Site 50
S338
L
N
V
Q
N
K
N
S
S
Y
F
V
E
W
I
Site 51
S339
N
V
Q
N
K
N
S
S
Y
F
V
E
W
I
P
Site 52
Y340
V
Q
N
K
N
S
S
Y
F
V
E
W
I
P
N
Site 53
S364
P
P
R
G
L
K
M
S
A
T
F
I
G
N
S
Site 54
T366
R
G
L
K
M
S
A
T
F
I
G
N
S
T
A
Site 55
S382
Q
E
L
F
K
R
I
S
E
Q
F
T
A
M
F
Site 56
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Site 57
Y425
L
V
S
E
Y
Q
Q
Y
Q
D
A
T
A
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation