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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAMB3
Full Name:
Laminin subunit beta-3
Alias:
Laminin 5 beta 3
Type:
Mass (Da):
129555
Number AA:
1172
UniProt ID:
Q13751
International Prot ID:
IPI00299404
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005578
GO:0005604
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0008544
GO:0009888
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
R
T
R
F
L
R
A
S
S
T
C
G
L
T
K
Site 2
S45
T
R
F
L
R
A
S
S
T
C
G
L
T
K
P
Site 3
T54
C
G
L
T
K
P
E
T
Y
C
T
Q
Y
G
E
Site 4
Y55
G
L
T
K
P
E
T
Y
C
T
Q
Y
G
E
W
Site 5
Y77
D
S
R
Q
P
H
N
Y
Y
S
H
R
V
E
N
Site 6
Y78
S
R
Q
P
H
N
Y
Y
S
H
R
V
E
N
V
Site 7
S87
H
R
V
E
N
V
A
S
S
S
G
P
M
R
W
Site 8
S105
Q
N
D
V
N
P
V
S
L
Q
L
D
L
D
R
Site 9
S136
A
G
M
L
I
E
R
S
S
D
F
G
K
T
W
Site 10
S137
G
M
L
I
E
R
S
S
D
F
G
K
T
W
R
Site 11
T142
R
S
S
D
F
G
K
T
W
R
V
Y
Q
Y
L
Site 12
Y146
F
G
K
T
W
R
V
Y
Q
Y
L
A
A
D
C
Site 13
Y148
K
T
W
R
V
Y
Q
Y
L
A
A
D
C
T
S
Site 14
T156
L
A
A
D
C
T
S
T
F
P
R
V
R
Q
G
Site 15
S167
V
R
Q
G
R
P
Q
S
W
Q
D
V
R
C
Q
Site 16
S175
W
Q
D
V
R
C
Q
S
L
P
Q
R
P
N
A
Site 17
T203
L
V
S
G
I
P
A
T
Q
S
Q
K
I
Q
E
Site 18
S205
S
G
I
P
A
T
Q
S
Q
K
I
Q
E
V
G
Site 19
Y232
A
P
V
P
Q
R
G
Y
H
P
P
S
A
Y
Y
Site 20
S236
Q
R
G
Y
H
P
P
S
A
Y
Y
A
V
S
Q
Site 21
Y238
G
Y
H
P
P
S
A
Y
Y
A
V
S
Q
L
R
Site 22
S242
P
S
A
Y
Y
A
V
S
Q
L
R
L
Q
G
S
Site 23
S266
C
A
P
K
P
G
A
S
A
G
P
S
T
A
V
Site 24
S270
P
G
A
S
A
G
P
S
T
A
V
Q
V
H
D
Site 25
Y362
C
E
R
C
Q
L
H
Y
F
R
N
R
R
P
G
Site 26
S371
R
N
R
R
P
G
A
S
I
Q
E
T
C
I
S
Site 27
T396
G
A
P
C
D
P
V
T
G
Q
C
V
C
K
E
Site 28
T421
K
P
G
F
T
G
L
T
Y
A
N
P
Q
G
C
Site 29
Y422
P
G
F
T
G
L
T
Y
A
N
P
Q
G
C
H
Site 30
Y524
R
Q
C
P
D
R
T
Y
G
D
V
A
T
G
C
Site 31
T529
R
T
Y
G
D
V
A
T
G
C
R
A
C
D
C
Site 32
S550
G
P
G
C
D
K
A
S
G
R
C
L
C
R
P
Site 33
T606
F
G
R
L
R
N
A
T
A
S
L
W
S
G
P
Site 34
S608
R
L
R
N
A
T
A
S
L
W
S
G
P
G
L
Site 35
S629
S
R
I
L
D
A
K
S
K
I
E
Q
I
R
A
Site 36
S640
Q
I
R
A
V
L
S
S
P
A
V
T
E
Q
E
Site 37
S677
P
L
E
E
E
T
L
S
L
P
R
D
L
E
S
Site 38
S684
S
L
P
R
D
L
E
S
L
D
R
S
F
N
G
Site 39
S688
D
L
E
S
L
D
R
S
F
N
G
L
L
T
M
Site 40
T694
R
S
F
N
G
L
L
T
M
Y
Q
R
K
R
E
Site 41
Y696
F
N
G
L
L
T
M
Y
Q
R
K
R
E
Q
F
Site 42
S707
R
E
Q
F
E
K
I
S
S
A
D
P
S
G
A
Site 43
S708
E
Q
F
E
K
I
S
S
A
D
P
S
G
A
F
Site 44
S712
K
I
S
S
A
D
P
S
G
A
F
R
M
L
S
Site 45
S719
S
G
A
F
R
M
L
S
T
A
Y
E
Q
S
A
Site 46
S733
A
Q
A
A
Q
Q
V
S
D
S
S
R
L
L
D
Site 47
S735
A
A
Q
Q
V
S
D
S
S
R
L
L
D
Q
L
Site 48
S745
L
L
D
Q
L
R
D
S
R
R
E
A
E
R
L
Site 49
S764
G
G
G
G
G
T
G
S
P
K
L
V
A
L
R
Site 50
S776
A
L
R
L
E
M
S
S
L
P
D
L
T
P
T
Site 51
T781
M
S
S
L
P
D
L
T
P
T
F
N
K
L
C
Site 52
T783
S
L
P
D
L
T
P
T
F
N
K
L
C
G
N
Site 53
S791
F
N
K
L
C
G
N
S
R
Q
M
A
C
T
P
Site 54
T797
N
S
R
Q
M
A
C
T
P
I
S
C
P
G
E
Site 55
T812
L
C
P
Q
D
N
G
T
A
C
G
S
R
C
R
Site 56
S816
D
N
G
T
A
C
G
S
R
C
R
G
V
L
P
Site 57
S859
M
I
R
A
A
E
E
S
A
S
Q
I
Q
S
S
Site 58
S861
R
A
A
E
E
S
A
S
Q
I
Q
S
S
A
Q
Site 59
S865
E
S
A
S
Q
I
Q
S
S
A
Q
R
L
E
T
Site 60
S866
S
A
S
Q
I
Q
S
S
A
Q
R
L
E
T
Q
Site 61
T872
S
S
A
Q
R
L
E
T
Q
V
S
A
S
R
S
Site 62
S875
Q
R
L
E
T
Q
V
S
A
S
R
S
Q
M
E
Site 63
S879
T
Q
V
S
A
S
R
S
Q
M
E
E
D
V
R
Site 64
T888
M
E
E
D
V
R
R
T
R
L
L
I
Q
Q
V
Site 65
T900
Q
Q
V
R
D
F
L
T
D
P
D
T
D
A
A
Site 66
T904
D
F
L
T
D
P
D
T
D
A
A
T
I
Q
E
Site 67
T927
W
L
P
T
D
S
A
T
V
L
Q
K
M
N
E
Site 68
S950
P
N
V
D
L
V
L
S
Q
T
K
Q
D
I
A
Site 69
T991
V
G
N
L
R
Q
G
T
V
A
L
Q
E
A
Q
Site 70
T1000
A
L
Q
E
A
Q
D
T
M
Q
G
T
S
R
S
Site 71
S1007
T
M
Q
G
T
S
R
S
L
R
L
I
Q
D
R
Site 72
T1030
R
P
A
E
K
L
V
T
S
M
T
K
Q
L
G
Site 73
S1068
Q
Q
L
A
E
G
A
S
E
Q
A
L
S
A
Q
Site 74
S1073
G
A
S
E
Q
A
L
S
A
Q
E
G
F
E
R
Site 75
Y1085
F
E
R
I
K
Q
K
Y
A
E
L
K
D
R
L
Site 76
S1096
K
D
R
L
G
Q
S
S
M
L
G
E
Q
G
A
Site 77
S1107
E
Q
G
A
R
I
Q
S
V
K
T
E
A
E
E
Site 78
T1110
A
R
I
Q
S
V
K
T
E
A
E
E
L
F
G
Site 79
S1137
E
L
E
L
L
R
G
S
Q
A
I
M
L
R
S
Site 80
T1148
M
L
R
S
A
D
L
T
G
L
E
K
R
V
E
Site 81
T1170
G
R
V
L
Y
Y
A
T
C
K
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation