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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR50
Full Name:
Melatonin-related receptor
Alias:
G protein-coupled receptor 50;H9
Type:
Mass (Da):
67355
Number AA:
617
UniProt ID:
Q13585
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S62
K
N
K
K
L
R
N
S
G
N
I
F
V
V
S
Site 2
Y136
Y
I
C
H
S
L
Q
Y
E
R
I
F
S
V
R
Site 3
Y171
M
Y
I
G
T
I
E
Y
D
P
R
T
Y
T
C
Site 4
Y176
I
E
Y
D
P
R
T
Y
T
C
I
F
N
Y
L
Site 5
T361
A
C
P
A
V
E
E
T
P
M
N
V
R
N
V
Site 6
S383
A
G
H
P
D
R
A
S
G
H
P
K
P
H
S
Site 7
S390
S
G
H
P
K
P
H
S
R
S
S
S
A
Y
R
Site 8
S392
H
P
K
P
H
S
R
S
S
S
A
Y
R
K
S
Site 9
S393
P
K
P
H
S
R
S
S
S
A
Y
R
K
S
A
Site 10
S394
K
P
H
S
R
S
S
S
A
Y
R
K
S
A
S
Site 11
Y396
H
S
R
S
S
S
A
Y
R
K
S
A
S
T
H
Site 12
S399
S
S
S
A
Y
R
K
S
A
S
T
H
H
K
S
Site 13
S401
S
A
Y
R
K
S
A
S
T
H
H
K
S
V
F
Site 14
T402
A
Y
R
K
S
A
S
T
H
H
K
S
V
F
S
Site 15
S406
S
A
S
T
H
H
K
S
V
F
S
H
S
K
A
Site 16
S409
T
H
H
K
S
V
F
S
H
S
K
A
A
S
G
Site 17
S411
H
K
S
V
F
S
H
S
K
A
A
S
G
H
L
Site 18
S415
F
S
H
S
K
A
A
S
G
H
L
K
P
V
S
Site 19
S422
S
G
H
L
K
P
V
S
G
H
S
K
P
A
S
Site 20
S425
L
K
P
V
S
G
H
S
K
P
A
S
G
H
P
Site 21
S429
S
G
H
S
K
P
A
S
G
H
P
K
S
A
T
Site 22
S434
P
A
S
G
H
P
K
S
A
T
V
Y
P
K
P
Site 23
T436
S
G
H
P
K
S
A
T
V
Y
P
K
P
A
S
Site 24
Y438
H
P
K
S
A
T
V
Y
P
K
P
A
S
V
H
Site 25
S443
T
V
Y
P
K
P
A
S
V
H
F
K
G
D
S
Site 26
S450
S
V
H
F
K
G
D
S
V
H
F
K
G
D
S
Site 27
S457
S
V
H
F
K
G
D
S
V
H
F
K
P
D
S
Site 28
S464
S
V
H
F
K
P
D
S
V
H
F
K
P
A
S
Site 29
S471
S
V
H
F
K
P
A
S
S
N
P
K
P
I
T
Site 30
S472
V
H
F
K
P
A
S
S
N
P
K
P
I
T
G
Site 31
T478
S
S
N
P
K
P
I
T
G
H
H
V
S
A
G
Site 32
S483
P
I
T
G
H
H
V
S
A
G
S
H
S
K
S
Site 33
S486
G
H
H
V
S
A
G
S
H
S
K
S
A
F
S
Site 34
S488
H
V
S
A
G
S
H
S
K
S
A
F
S
A
A
Site 35
S490
S
A
G
S
H
S
K
S
A
F
S
A
A
T
S
Site 36
S493
S
H
S
K
S
A
F
S
A
A
T
S
H
P
K
Site 37
T496
K
S
A
F
S
A
A
T
S
H
P
K
P
I
K
Site 38
S497
S
A
F
S
A
A
T
S
H
P
K
P
I
K
P
Site 39
T506
P
K
P
I
K
P
A
T
S
H
A
E
P
T
T
Site 40
T522
D
Y
P
K
P
A
T
T
S
H
P
K
P
A
A
Site 41
S577
P
A
A
S
Q
L
E
S
D
T
I
A
D
L
P
Site 42
Y596
V
T
T
S
T
N
D
Y
H
D
V
V
V
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation