KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
BFSP2
Full Name:
Phakinin
Alias:
49 kDa cytoskeletal protein; Beaded filament structural 2; Beaded filament structural protein 2; Beaded filament structural protein 2, phakinin; CP 47; CP47; CP49; Lens fiber cell beaded filament protein CP 49; Lens intermediate filament-like light; LIFL-L
Type:
Cytoskeletal protein
Mass (Da):
45861
Number AA:
415
UniProt ID:
Q13515
International Prot ID:
IPI00299007
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005882
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005200
GO:0005212
PhosphoSite+
KinaseNET
Biological Process:
GO:0050896
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
E
R
R
V
V
V
D
Site 2
S15
V
D
L
P
T
S
A
S
S
S
M
P
L
Q
R
Site 3
S17
L
P
T
S
A
S
S
S
M
P
L
Q
R
R
R
Site 4
S26
P
L
Q
R
R
R
A
S
F
R
G
P
R
S
S
Site 5
S32
A
S
F
R
G
P
R
S
S
S
S
L
E
S
P
Site 6
S33
S
F
R
G
P
R
S
S
S
S
L
E
S
P
P
Site 7
S34
F
R
G
P
R
S
S
S
S
L
E
S
P
P
A
Site 8
S35
R
G
P
R
S
S
S
S
L
E
S
P
P
A
S
Site 9
S38
R
S
S
S
S
L
E
S
P
P
A
S
R
T
N
Site 10
S42
S
L
E
S
P
P
A
S
R
T
N
A
M
S
G
Site 11
T44
E
S
P
P
A
S
R
T
N
A
M
S
G
L
V
Site 12
S48
A
S
R
T
N
A
M
S
G
L
V
R
A
P
G
Site 13
S90
V
F
L
Q
G
L
R
S
S
G
L
A
T
V
P
Site 14
S142
Q
L
R
M
H
L
E
S
K
A
T
R
S
G
N
Site 15
T145
M
H
L
E
S
K
A
T
R
S
G
N
W
G
A
Site 16
S159
A
L
R
A
S
W
A
S
S
C
Q
Q
V
G
E
Site 17
S160
L
R
A
S
W
A
S
S
C
Q
Q
V
G
E
A
Site 18
T178
N
A
R
L
M
L
Q
T
E
T
I
Q
A
G
A
Site 19
Y192
A
D
D
F
K
E
R
Y
E
N
E
Q
P
F
R
Site 20
S208
A
A
E
E
E
I
N
S
L
Y
K
V
I
D
E
Site 21
Y210
E
E
E
I
N
S
L
Y
K
V
I
D
E
A
N
Site 22
T219
V
I
D
E
A
N
L
T
K
M
D
L
E
S
Q
Site 23
S225
L
T
K
M
D
L
E
S
Q
I
E
S
L
K
E
Site 24
S229
D
L
E
S
Q
I
E
S
L
K
E
E
L
G
S
Site 25
S236
S
L
K
E
E
L
G
S
L
S
R
N
Y
E
E
Site 26
S238
K
E
E
L
G
S
L
S
R
N
Y
E
E
D
V
Site 27
Y241
L
G
S
L
S
R
N
Y
E
E
D
V
K
L
L
Site 28
T274
G
L
D
D
I
L
E
T
I
R
I
Q
W
E
R
Site 29
T324
L
R
V
E
L
H
N
T
S
C
Q
V
Q
S
L
Site 30
S337
S
L
Q
A
E
T
E
S
L
R
A
L
K
R
G
Site 31
T348
L
K
R
G
L
E
N
T
L
H
D
A
K
H
W
Site 32
S404
Q
L
Q
K
D
V
A
S
Y
H
A
L
L
D
R
Site 33
S414
A
L
L
D
R
E
E
S
G
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation