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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
cIAP2
Full Name:
Baculoviral IAP repeat-containing protein 3
Alias:
AIP1; API2; Apoptosis inhibitor 2; Baculoviral IAP repeat-containing 3; BIRC3; CIAP2; C-IAP2; HAIP1; HIAP1; HIAP-1; IAP homolog C; IAP1; Inhibitor of apoptosis protein 1; MALT2; Mammalian IAP C; MIHC; RNF49; TNFR2-TRAF signaling complex protein
Type:
Apoptosis
Mass (Da):
68372
Number AA:
604
UniProt ID:
Q13489
International Prot ID:
IPI00013409
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004842
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006915
GO:0007166
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
N
I
V
E
N
S
I
F
L
S
N
L
M
Site 2
S11
V
E
N
S
I
F
L
S
N
L
M
K
S
A
N
Site 3
S16
F
L
S
N
L
M
K
S
A
N
T
F
E
L
K
Site 4
Y24
A
N
T
F
E
L
K
Y
D
L
S
C
E
L
Y
Site 5
S27
F
E
L
K
Y
D
L
S
C
E
L
Y
R
M
S
Site 6
Y31
Y
D
L
S
C
E
L
Y
R
M
S
T
Y
S
T
Site 7
S34
S
C
E
L
Y
R
M
S
T
Y
S
T
F
P
A
Site 8
T35
C
E
L
Y
R
M
S
T
Y
S
T
F
P
A
G
Site 9
S37
L
Y
R
M
S
T
Y
S
T
F
P
A
G
V
P
Site 10
T38
Y
R
M
S
T
Y
S
T
F
P
A
G
V
P
V
Site 11
S49
G
V
P
V
S
E
R
S
L
A
R
A
G
F
Y
Site 12
Y57
L
A
R
A
G
F
Y
Y
T
G
V
N
D
K
V
Site 13
S81
D
N
W
K
R
G
D
S
P
T
E
K
H
K
K
Site 14
T83
W
K
R
G
D
S
P
T
E
K
H
K
K
L
Y
Site 15
Y90
T
E
K
H
K
K
L
Y
P
S
C
R
F
V
Q
Site 16
S92
K
H
K
K
L
Y
P
S
C
R
F
V
Q
S
L
Site 17
S98
P
S
C
R
F
V
Q
S
L
N
S
V
N
N
L
Site 18
S101
R
F
V
Q
S
L
N
S
V
N
N
L
E
A
T
Site 19
S109
V
N
N
L
E
A
T
S
Q
P
T
F
P
S
S
Site 20
T112
L
E
A
T
S
Q
P
T
F
P
S
S
V
T
N
Site 21
S116
S
Q
P
T
F
P
S
S
V
T
N
S
T
H
S
Site 22
S120
F
P
S
S
V
T
N
S
T
H
S
L
L
P
G
Site 23
T121
P
S
S
V
T
N
S
T
H
S
L
L
P
G
T
Site 24
S123
S
V
T
N
S
T
H
S
L
L
P
G
T
E
N
Site 25
T128
T
H
S
L
L
P
G
T
E
N
S
G
Y
F
R
Site 26
S131
L
L
P
G
T
E
N
S
G
Y
F
R
G
S
Y
Site 27
Y133
P
G
T
E
N
S
G
Y
F
R
G
S
Y
S
N
Site 28
S137
N
S
G
Y
F
R
G
S
Y
S
N
S
P
S
N
Site 29
Y138
S
G
Y
F
R
G
S
Y
S
N
S
P
S
N
P
Site 30
S139
G
Y
F
R
G
S
Y
S
N
S
P
S
N
P
V
Site 31
S141
F
R
G
S
Y
S
N
S
P
S
N
P
V
N
S
Site 32
S143
G
S
Y
S
N
S
P
S
N
P
V
N
S
R
A
Site 33
S148
S
P
S
N
P
V
N
S
R
A
N
Q
D
F
S
Site 34
S155
S
R
A
N
Q
D
F
S
A
L
M
R
S
S
Y
Site 35
Y162
S
A
L
M
R
S
S
Y
H
C
A
M
N
N
E
Site 36
T175
N
E
N
A
R
L
L
T
F
Q
T
W
P
L
T
Site 37
T242
I
E
N
Q
L
Q
D
T
S
R
Y
T
V
S
N
Site 38
Y245
Q
L
Q
D
T
S
R
Y
T
V
S
N
L
S
M
Site 39
T246
L
Q
D
T
S
R
Y
T
V
S
N
L
S
M
Q
Site 40
S248
D
T
S
R
Y
T
V
S
N
L
S
M
Q
T
H
Site 41
T254
V
S
N
L
S
M
Q
T
H
A
A
R
F
K
T
Site 42
T261
T
H
A
A
R
F
K
T
F
F
N
W
P
S
S
Site 43
S268
T
F
F
N
W
P
S
S
V
L
V
N
P
E
Q
Site 44
Y282
Q
L
A
S
A
G
F
Y
Y
V
G
N
S
D
D
Site 45
Y321
K
W
F
P
R
C
E
Y
L
I
R
I
K
G
Q
Site 46
S337
F
I
R
Q
V
Q
A
S
Y
P
H
L
L
E
Q
Site 47
Y338
I
R
Q
V
Q
A
S
Y
P
H
L
L
E
Q
L
Site 48
S347
H
L
L
E
Q
L
L
S
T
S
D
S
P
G
D
Site 49
S349
L
E
Q
L
L
S
T
S
D
S
P
G
D
E
N
Site 50
S351
Q
L
L
S
T
S
D
S
P
G
D
E
N
A
E
Site 51
S359
P
G
D
E
N
A
E
S
S
I
I
H
F
E
P
Site 52
S360
G
D
E
N
A
E
S
S
I
I
H
F
E
P
G
Site 53
S393
V
E
M
G
F
S
R
S
L
V
K
Q
T
V
Q
Site 54
T406
V
Q
R
K
I
L
A
T
G
E
N
Y
R
L
V
Site 55
T436
E
E
E
R
E
R
A
T
E
E
K
E
S
N
D
Site 56
S441
R
A
T
E
E
K
E
S
N
D
L
L
L
I
R
Site 57
Y522
Q
E
A
E
A
V
L
Y
E
H
L
F
V
Q
Q
Site 58
Y533
F
V
Q
Q
D
I
K
Y
I
P
T
E
D
V
S
Site 59
T536
Q
D
I
K
Y
I
P
T
E
D
V
S
D
L
P
Site 60
S540
Y
I
P
T
E
D
V
S
D
L
P
V
E
E
Q
Site 61
S593
R
K
C
P
I
C
R
S
T
I
K
G
T
V
R
Site 62
T594
K
C
P
I
C
R
S
T
I
K
G
T
V
R
T
Site 63
T598
C
R
S
T
I
K
G
T
V
R
T
F
L
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation