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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FZD5
Full Name:
Frizzled-5
Alias:
C2orf31; DKFZP434E2135; Frizzled 5; Fz-5; FzE5; HFZ5; Wnt receptor
Type:
Receptor, GPCR
Mass (Da):
64507
Number AA:
585
UniProt ID:
Q13467
International Prot ID:
IPI00298743
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004930
GO:0004926
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0016055
GO:0007164
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
R
P
D
P
S
A
P
P
S
L
L
L
Site 2
S11
P
D
P
S
A
P
P
S
L
L
L
L
L
L
A
Site 3
T59
P
N
Q
F
N
H
D
T
Q
D
E
A
G
L
E
Site 4
Y98
T
P
I
C
L
P
D
Y
H
K
P
L
P
P
C
Site 5
S107
K
P
L
P
P
C
R
S
V
C
E
R
A
K
A
Site 6
S117
E
R
A
K
A
G
C
S
P
L
M
R
Q
Y
G
Site 7
Y123
C
S
P
L
M
R
Q
Y
G
F
A
W
P
E
R
Site 8
S132
F
A
W
P
E
R
M
S
C
D
R
L
P
V
L
Site 9
Y150
A
E
V
L
C
M
D
Y
N
R
S
E
A
T
T
Site 10
S153
L
C
M
D
Y
N
R
S
E
A
T
T
A
P
P
Site 11
T157
Y
N
R
S
E
A
T
T
A
P
P
R
P
F
P
Site 12
T168
R
P
F
P
A
K
P
T
L
P
G
P
P
G
A
Site 13
S178
G
P
P
G
A
P
A
S
G
G
E
C
P
A
G
Site 14
Y207
L
K
E
S
H
P
L
Y
N
K
V
R
T
G
Q
Site 15
Y223
P
N
C
A
V
P
C
Y
Q
P
S
F
S
A
D
Site 16
S226
A
V
P
C
Y
Q
P
S
F
S
A
D
E
R
T
Site 17
S228
P
C
Y
Q
P
S
F
S
A
D
E
R
T
F
A
Site 18
T233
S
F
S
A
D
E
R
T
F
A
T
F
W
I
G
Site 19
Y266
I
D
M
E
R
F
R
Y
P
E
R
P
I
I
F
Site 20
S295
R
L
V
V
G
H
A
S
V
A
C
S
R
E
H
Site 21
Y307
R
E
H
N
H
I
H
Y
E
T
T
G
P
A
L
Site 22
Y391
D
P
V
A
G
I
C
Y
V
G
N
Q
N
L
N
Site 23
T440
I
K
Q
G
G
T
K
T
D
K
L
E
K
L
M
Site 24
Y470
I
V
V
A
C
Y
L
Y
E
Q
H
Y
R
E
S
Site 25
T491
C
A
C
P
G
H
D
T
G
Q
P
R
A
K
P
Site 26
Y500
Q
P
R
A
K
P
E
Y
W
V
L
M
L
K
Y
Site 27
S529
W
S
G
K
T
V
E
S
W
R
R
F
T
S
R
Site 28
S547
R
P
R
R
G
H
K
S
G
G
A
M
A
A
G
Site 29
Y556
G
A
M
A
A
G
D
Y
P
E
A
S
A
A
L
Site 30
S560
A
G
D
Y
P
E
A
S
A
A
L
T
G
R
T
Site 31
T564
P
E
A
S
A
A
L
T
G
R
T
G
P
P
G
Site 32
T567
S
A
A
L
T
G
R
T
G
P
P
G
P
A
A
Site 33
T575
G
P
P
G
P
A
A
T
Y
H
K
Q
V
S
L
Site 34
Y576
P
P
G
P
A
A
T
Y
H
K
Q
V
S
L
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation