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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYO9B
Full Name:
Myosin-IXb
Alias:
CELIAC4; Myosin IXb; Myosin-9B; Myosin-IXb: Unconventional myosin-9b: Myosin-IXb: Unconventional myosin-9b: MYO9B variant protein; MYR5; Unconventional myosin-9b
Type:
Motor protein
Mass (Da):
243558
Number AA:
2158
UniProt ID:
Q13459
International Prot ID:
IPI00336047
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005938
GO:0031941
GO:0016459
Uniprot
OncoNet
Molecular Function:
GO:0043531
GO:0005524
GO:0005100
PhosphoSite+
KinaseNET
Biological Process:
GO:0007266
GO:0030048
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
V
K
E
A
G
S
S
Site 2
S9
S
V
K
E
A
G
S
S
G
R
R
E
Q
A
A
Site 3
Y17
G
R
R
E
Q
A
A
Y
H
L
H
I
Y
P
Q
Site 4
Y22
A
A
Y
H
L
H
I
Y
P
Q
L
S
T
T
E
Site 5
S26
L
H
I
Y
P
Q
L
S
T
T
E
S
Q
A
S
Site 6
T28
I
Y
P
Q
L
S
T
T
E
S
Q
A
S
C
R
Site 7
S30
P
Q
L
S
T
T
E
S
Q
A
S
C
R
V
T
Site 8
S33
S
T
T
E
S
Q
A
S
C
R
V
T
A
T
K
Site 9
T37
S
Q
A
S
C
R
V
T
A
T
K
D
S
T
T
Site 10
T43
V
T
A
T
K
D
S
T
T
S
D
V
I
K
D
Site 11
Y63
R
L
D
G
T
K
C
Y
V
L
V
E
V
K
E
Site 12
S83
W
V
L
D
A
N
D
S
P
V
H
R
V
L
L
Site 13
Y105
E
H
P
Q
E
D
G
Y
Y
F
L
L
Q
E
R
Site 14
Y106
H
P
Q
E
D
G
Y
Y
F
L
L
Q
E
R
N
Site 15
Y176
R
F
L
Q
Q
K
I
Y
T
Y
A
G
S
I
L
Site 16
Y195
P
F
K
F
L
P
I
Y
N
P
K
Y
V
K
M
Site 17
Y199
L
P
I
Y
N
P
K
Y
V
K
M
Y
E
N
Q
Site 18
Y203
N
P
K
Y
V
K
M
Y
E
N
Q
Q
L
G
K
Site 19
Y237
R
V
N
Q
C
I
V
Y
P
G
E
S
G
S
G
Site 20
S241
C
I
V
Y
P
G
E
S
G
S
G
K
T
Q
S
Site 21
S243
V
Y
P
G
E
S
G
S
G
K
T
Q
S
T
N
Site 22
S248
S
G
S
G
K
T
Q
S
T
N
F
L
I
H
C
Site 23
Y264
T
A
L
S
Q
K
G
Y
A
S
G
V
E
R
T
Site 24
S293
K
T
A
H
N
N
N
S
S
R
F
G
K
F
I
Site 25
Y318
R
G
A
V
V
E
K
Y
L
L
E
K
S
R
L
Site 26
S323
E
K
Y
L
L
E
K
S
R
L
V
S
Q
E
K
Site 27
S327
L
E
K
S
R
L
V
S
Q
E
K
D
E
R
N
Site 28
Y335
Q
E
K
D
E
R
N
Y
H
V
F
Y
Y
L
L
Site 29
S346
Y
Y
L
L
L
G
V
S
E
E
E
R
Q
E
F
Site 30
Y361
Q
L
K
Q
P
E
D
Y
F
Y
L
N
Q
H
N
Site 31
Y363
K
Q
P
E
D
Y
F
Y
L
N
Q
H
N
L
K
Site 32
Y416
L
Y
L
G
N
V
T
Y
K
K
R
A
T
G
R
Site 33
T421
V
T
Y
K
K
R
A
T
G
R
E
E
G
L
E
Site 34
S439
P
E
V
L
D
T
L
S
Q
L
L
K
V
K
R
Site 35
T458
E
V
L
T
K
R
K
T
V
T
V
N
D
K
L
Site 36
T460
L
T
K
R
K
T
V
T
V
N
D
K
L
I
L
Site 37
T476
Y
S
L
S
E
A
I
T
A
R
D
S
M
A
K
Site 38
S480
E
A
I
T
A
R
D
S
M
A
K
S
L
Y
S
Site 39
S484
A
R
D
S
M
A
K
S
L
Y
S
A
L
F
D
Site 40
Y539
F
E
Q
F
C
I
N
Y
A
N
E
Q
L
Q
Y
Site 41
Y546
Y
A
N
E
Q
L
Q
Y
Y
F
N
Q
H
I
F
Site 42
Y547
A
N
E
Q
L
Q
Y
Y
F
N
Q
H
I
F
K
Site 43
Y560
F
K
L
E
Q
E
E
Y
Q
G
E
G
I
T
W
Site 44
Y591
K
K
P
T
G
L
F
Y
L
L
D
E
E
S
N
Site 45
S597
F
Y
L
L
D
E
E
S
N
F
P
H
A
T
S
Site 46
S604
S
N
F
P
H
A
T
S
Q
T
L
L
A
K
F
Site 47
Y620
Q
Q
H
E
D
N
K
Y
F
L
G
T
P
V
M
Site 48
T624
D
N
K
Y
F
L
G
T
P
V
M
E
P
A
F
Site 49
Y642
H
F
A
G
K
V
K
Y
Q
I
K
D
F
R
E
Site 50
Y654
F
R
E
K
N
M
D
Y
M
R
P
D
I
V
A
Site 51
S666
I
V
A
L
L
R
G
S
D
S
S
Y
V
R
E
Site 52
S668
A
L
L
R
G
S
D
S
S
Y
V
R
E
L
I
Site 53
S669
L
L
R
G
S
D
S
S
Y
V
R
E
L
I
G
Site 54
Y670
L
R
G
S
D
S
S
Y
V
R
E
L
I
G
M
Site 55
S716
A
E
K
A
A
G
M
S
S
P
G
A
Q
S
H
Site 56
S717
E
K
A
A
G
M
S
S
P
G
A
Q
S
H
P
Site 57
S722
M
S
S
P
G
A
Q
S
H
P
E
E
L
P
R
Site 58
S732
E
E
L
P
R
G
A
S
T
P
S
E
K
L
Y
Site 59
T733
E
L
P
R
G
A
S
T
P
S
E
K
L
Y
R
Site 60
Y739
S
T
P
S
E
K
L
Y
R
D
L
H
N
Q
M
Site 61
S762
W
Q
G
E
D
P
R
S
L
L
Q
S
L
S
R
Site 62
S766
D
P
R
S
L
L
Q
S
L
S
R
L
Q
K
P
Site 63
S768
R
S
L
L
Q
S
L
S
R
L
Q
K
P
R
A
Site 64
S780
P
R
A
F
I
L
K
S
K
G
I
K
Q
K
Q
Site 65
S804
K
S
L
K
L
I
I
S
M
T
L
H
D
R
T
Site 66
T806
L
K
L
I
I
S
M
T
L
H
D
R
T
T
K
Site 67
T811
S
M
T
L
H
D
R
T
T
K
S
L
L
H
L
Site 68
T812
M
T
L
H
D
R
T
T
K
S
L
L
H
L
H
Site 69
S814
L
H
D
R
T
T
K
S
L
L
H
L
H
K
K
Site 70
S826
H
K
K
K
K
P
P
S
I
S
A
Q
F
Q
T
Site 71
S828
K
K
K
P
P
S
I
S
A
Q
F
Q
T
S
L
Site 72
S834
I
S
A
Q
F
Q
T
S
L
N
K
L
L
E
A
Site 73
S855
F
F
I
R
C
I
R
S
N
A
E
K
K
E
L
Site 74
Y875
L
V
L
Q
Q
L
R
Y
T
G
M
L
E
T
V
Site 75
T876
V
L
Q
Q
L
R
Y
T
G
M
L
E
T
V
R
Site 76
T881
R
Y
T
G
M
L
E
T
V
R
I
R
R
S
G
Site 77
S887
E
T
V
R
I
R
R
S
G
Y
S
A
K
Y
T
Site 78
Y889
V
R
I
R
R
S
G
Y
S
A
K
Y
T
F
Q
Site 79
S890
R
I
R
R
S
G
Y
S
A
K
Y
T
F
Q
D
Site 80
Y893
R
S
G
Y
S
A
K
Y
T
F
Q
D
F
T
E
Site 81
T894
S
G
Y
S
A
K
Y
T
F
Q
D
F
T
E
Q
Site 82
T919
P
C
R
E
V
I
S
T
L
L
E
K
M
K
I
Site 83
Y931
M
K
I
D
K
R
N
Y
Q
I
G
K
T
K
V
Site 84
T951
E
R
Q
A
L
Q
E
T
L
H
R
E
V
V
R
Site 85
Y993
I
Q
A
C
W
R
S
Y
R
V
R
R
A
L
E
Site 86
T1002
V
R
R
A
L
E
R
T
Q
A
A
V
Y
L
Q
Site 87
Y1015
L
Q
A
A
W
R
G
Y
W
Q
R
K
L
Y
R
Site 88
Y1021
G
Y
W
Q
R
K
L
Y
R
H
Q
K
Q
S
I
Site 89
S1027
L
Y
R
H
Q
K
Q
S
I
I
R
L
Q
S
L
Site 90
S1033
Q
S
I
I
R
L
Q
S
L
C
R
G
H
L
Q
Site 91
S1043
R
G
H
L
Q
R
K
S
F
S
Q
M
I
S
E
Site 92
S1045
H
L
Q
R
K
S
F
S
Q
M
I
S
E
K
Q
Site 93
S1049
K
S
F
S
Q
M
I
S
E
K
Q
K
A
E
E
Site 94
S1099
E
D
G
G
H
L
A
S
E
P
E
V
Q
P
S
Site 95
S1106
S
E
P
E
V
Q
P
S
D
R
S
P
L
E
H
Site 96
S1109
E
V
Q
P
S
D
R
S
P
L
E
H
S
S
P
Site 97
S1114
D
R
S
P
L
E
H
S
S
P
E
K
E
A
P
Site 98
S1115
R
S
P
L
E
H
S
S
P
E
K
E
A
P
S
Site 99
S1122
S
P
E
K
E
A
P
S
P
E
K
T
L
P
P
Site 100
T1126
E
A
P
S
P
E
K
T
L
P
P
Q
K
T
V
Site 101
T1132
K
T
L
P
P
Q
K
T
V
A
A
E
S
H
E
Site 102
S1137
Q
K
T
V
A
A
E
S
H
E
K
V
P
S
S
Site 103
S1143
E
S
H
E
K
V
P
S
S
R
E
K
R
E
S
Site 104
S1144
S
H
E
K
V
P
S
S
R
E
K
R
E
S
R
Site 105
S1150
S
S
R
E
K
R
E
S
R
R
Q
R
G
L
E
Site 106
S1168
F
Q
N
K
H
I
Q
S
C
K
E
E
S
A
L
Site 107
S1173
I
Q
S
C
K
E
E
S
A
L
R
E
P
S
R
Site 108
S1179
E
S
A
L
R
E
P
S
R
R
V
T
Q
E
Q
Site 109
T1183
R
E
P
S
R
R
V
T
Q
E
Q
G
V
S
L
Site 110
S1189
V
T
Q
E
Q
G
V
S
L
L
E
D
K
K
E
Site 111
T1202
K
E
S
R
E
D
E
T
L
L
V
V
E
T
E
Site 112
T1237
V
S
E
E
T
E
K
T
L
P
S
G
S
P
R
Site 113
S1240
E
T
E
K
T
L
P
S
G
S
P
R
P
G
Q
Site 114
S1242
E
K
T
L
P
S
G
S
P
R
P
G
Q
L
E
Site 115
T1252
P
G
Q
L
E
R
P
T
S
L
A
L
D
S
R
Site 116
S1253
G
Q
L
E
R
P
T
S
L
A
L
D
S
R
V
Site 117
S1258
P
T
S
L
A
L
D
S
R
V
S
P
P
A
P
Site 118
S1261
L
A
L
D
S
R
V
S
P
P
A
P
G
S
A
Site 119
S1267
V
S
P
P
A
P
G
S
A
P
E
T
P
E
D
Site 120
T1271
A
P
G
S
A
P
E
T
P
E
D
K
S
K
P
Site 121
S1276
P
E
T
P
E
D
K
S
K
P
C
G
S
P
R
Site 122
S1281
D
K
S
K
P
C
G
S
P
R
V
Q
E
K
P
Site 123
S1290
R
V
Q
E
K
P
D
S
P
G
G
S
T
Q
I
Site 124
S1294
K
P
D
S
P
G
G
S
T
Q
I
Q
R
Y
L
Site 125
T1295
P
D
S
P
G
G
S
T
Q
I
Q
R
Y
L
D
Site 126
S1308
L
D
A
E
R
L
A
S
A
V
E
L
W
R
G
Site 127
S1323
K
K
L
V
A
A
A
S
P
S
A
M
L
S
Q
Site 128
S1325
L
V
A
A
A
S
P
S
A
M
L
S
Q
S
L
Site 129
S1329
A
S
P
S
A
M
L
S
Q
S
L
D
L
S
D
Site 130
S1331
P
S
A
M
L
S
Q
S
L
D
L
S
D
R
H
Site 131
S1335
L
S
Q
S
L
D
L
S
D
R
H
R
A
T
G
Site 132
T1341
L
S
D
R
H
R
A
T
G
A
A
L
T
P
T
Site 133
T1346
R
A
T
G
A
A
L
T
P
T
E
E
R
R
T
Site 134
T1348
T
G
A
A
L
T
P
T
E
E
R
R
T
S
F
Site 135
T1353
T
P
T
E
E
R
R
T
S
F
S
T
S
D
V
Site 136
S1354
P
T
E
E
R
R
T
S
F
S
T
S
D
V
S
Site 137
S1356
E
E
R
R
T
S
F
S
T
S
D
V
S
K
L
Site 138
T1357
E
R
R
T
S
F
S
T
S
D
V
S
K
L
L
Site 139
S1358
R
R
T
S
F
S
T
S
D
V
S
K
L
L
P
Site 140
S1361
S
F
S
T
S
D
V
S
K
L
L
P
S
L
A
Site 141
S1366
D
V
S
K
L
L
P
S
L
A
K
A
Q
P
A
Site 142
S1397
K
K
K
P
G
D
A
S
S
L
P
D
A
G
L
Site 143
S1398
K
K
P
G
D
A
S
S
L
P
D
A
G
L
S
Site 144
S1405
S
L
P
D
A
G
L
S
P
G
S
Q
V
D
S
Site 145
S1408
D
A
G
L
S
P
G
S
Q
V
D
S
K
S
T
Site 146
S1412
S
P
G
S
Q
V
D
S
K
S
T
F
K
R
L
Site 147
S1414
G
S
Q
V
D
S
K
S
T
F
K
R
L
F
L
Site 148
T1415
S
Q
V
D
S
K
S
T
F
K
R
L
F
L
H
Site 149
T1424
K
R
L
F
L
H
K
T
K
D
K
K
Y
S
L
Site 150
Y1429
H
K
T
K
D
K
K
Y
S
L
E
G
A
E
E
Site 151
S1430
K
T
K
D
K
K
Y
S
L
E
G
A
E
E
L
Site 152
T1473
H
A
A
G
E
K
R
T
K
E
P
G
G
K
G
Site 153
S1494
K
I
G
K
I
T
V
S
E
K
W
R
E
S
V
Site 154
S1500
V
S
E
K
W
R
E
S
V
F
R
Q
I
T
N
Site 155
T1506
E
S
V
F
R
Q
I
T
N
A
N
E
L
K
Y
Site 156
Y1513
T
N
A
N
E
L
K
Y
L
D
E
F
L
L
N
Site 157
S1527
N
K
I
N
D
L
R
S
Q
K
T
P
I
E
S
Site 158
T1530
N
D
L
R
S
Q
K
T
P
I
E
S
L
F
I
Site 159
T1540
E
S
L
F
I
E
A
T
E
K
F
R
S
N
I
Site 160
S1545
E
A
T
E
K
F
R
S
N
I
K
T
M
Y
S
Site 161
T1549
K
F
R
S
N
I
K
T
M
Y
S
V
P
N
G
Site 162
Y1551
R
S
N
I
K
T
M
Y
S
V
P
N
G
K
I
Site 163
S1552
S
N
I
K
T
M
Y
S
V
P
N
G
K
I
H
Site 164
Y1562
N
G
K
I
H
V
G
Y
K
D
L
M
E
N
Y
Site 165
Y1569
Y
K
D
L
M
E
N
Y
Q
I
V
V
S
N
L
Site 166
S1574
E
N
Y
Q
I
V
V
S
N
L
A
T
E
R
G
Site 167
T1578
I
V
V
S
N
L
A
T
E
R
G
Q
K
D
T
Site 168
T1585
T
E
R
G
Q
K
D
T
N
L
V
L
N
L
F
Site 169
Y1603
L
D
E
F
T
R
G
Y
T
K
N
D
F
E
P
Site 170
T1604
D
E
F
T
R
G
Y
T
K
N
D
F
E
P
V
Site 171
Y1638
N
G
H
V
F
A
S
Y
Q
V
S
I
P
Q
S
Site 172
S1641
V
F
A
S
Y
Q
V
S
I
P
Q
S
C
E
Q
Site 173
Y1683
K
I
Q
S
H
C
S
Y
T
Y
G
R
K
G
E
Site 174
T1684
I
Q
S
H
C
S
Y
T
Y
G
R
K
G
E
P
Site 175
Y1685
Q
S
H
C
S
Y
T
Y
G
R
K
G
E
P
G
Site 176
S1704
H
F
G
V
C
V
D
S
L
T
S
D
K
A
S
Site 177
S1711
S
L
T
S
D
K
A
S
V
P
I
V
L
E
K
Site 178
Y1729
H
V
E
M
H
G
L
Y
T
E
G
L
Y
R
K
Site 179
Y1734
G
L
Y
T
E
G
L
Y
R
K
S
G
A
A
N
Site 180
S1737
T
E
G
L
Y
R
K
S
G
A
A
N
R
T
R
Site 181
T1752
E
L
R
Q
A
L
Q
T
D
P
A
A
V
K
L
Site 182
T1784
E
L
P
E
P
L
M
T
F
A
Q
Y
G
D
F
Site 183
S1821
L
P
E
A
N
H
N
S
L
E
R
L
I
F
H
Site 184
S1861
L
L
R
C
P
D
N
S
D
P
L
T
S
M
K
Site 185
T1865
P
D
N
S
D
P
L
T
S
M
K
D
V
L
K
Site 186
S1866
D
N
S
D
P
L
T
S
M
K
D
V
L
K
I
Site 187
Y1888
I
K
E
Q
M
R
K
Y
K
V
K
M
E
E
I
Site 188
S1903
S
Q
L
E
A
A
E
S
I
A
F
R
R
L
S
Site 189
S1910
S
I
A
F
R
R
L
S
L
L
R
Q
N
A
P
Site 190
S1925
W
P
L
K
L
G
F
S
S
P
Y
E
G
V
L
Site 191
S1926
P
L
K
L
G
F
S
S
P
Y
E
G
V
L
N
Site 192
Y1928
K
L
G
F
S
S
P
Y
E
G
V
L
N
K
S
Site 193
S1935
Y
E
G
V
L
N
K
S
P
Q
V
P
R
D
I
Site 194
S1973
I
L
I
E
R
I
Q
S
I
K
E
E
K
E
D
Site 195
T1982
K
E
E
K
E
D
I
T
Y
R
L
P
E
L
D
Site 196
Y1983
E
E
K
E
D
I
T
Y
R
L
P
E
L
D
P
Site 197
S1993
P
E
L
D
P
R
G
S
D
E
E
N
L
D
S
Site 198
S2000
S
D
E
E
N
L
D
S
E
T
S
A
S
T
E
Site 199
T2002
E
E
N
L
D
S
E
T
S
A
S
T
E
S
L
Site 200
S2003
E
N
L
D
S
E
T
S
A
S
T
E
S
L
L
Site 201
S2005
L
D
S
E
T
S
A
S
T
E
S
L
L
E
E
Site 202
T2006
D
S
E
T
S
A
S
T
E
S
L
L
E
E
R
Site 203
S2008
E
T
S
A
S
T
E
S
L
L
E
E
R
A
G
Site 204
S2019
E
R
A
G
R
G
A
S
E
G
P
P
A
P
A
Site 205
T2040
P
T
P
S
P
L
P
T
V
A
A
P
P
R
R
Site 206
S2050
A
P
P
R
R
R
P
S
S
F
V
T
V
R
V
Site 207
S2051
P
P
R
R
R
P
S
S
F
V
T
V
R
V
K
Site 208
T2054
R
R
P
S
S
F
V
T
V
R
V
K
T
P
R
Site 209
T2059
F
V
T
V
R
V
K
T
P
R
R
T
P
I
M
Site 210
T2063
R
V
K
T
P
R
R
T
P
I
M
P
T
A
N
Site 211
S2079
K
L
P
P
G
L
P
S
H
L
P
R
W
A
P
Site 212
S2110
R
R
P
D
Q
I
H
S
V
Y
I
T
P
G
A
Site 213
Y2112
P
D
Q
I
H
S
V
Y
I
T
P
G
A
D
L
Site 214
Y2141
P
P
G
A
K
R
R
Y
S
D
P
P
T
Y
C
Site 215
S2142
P
G
A
K
R
R
Y
S
D
P
P
T
Y
C
L
Site 216
T2146
R
R
Y
S
D
P
P
T
Y
C
L
P
P
A
S
Site 217
Y2147
R
Y
S
D
P
P
T
Y
C
L
P
P
A
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation