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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TUSC3
Full Name:
Tumor suppressor candidate 3
Alias:
39 kda encoded by n33; D8s1992; M33; Mrt7; N33; Ost3a; Tusc3
Type:
Putative regulator of N-glycosylation through its association with N-oligosaccharyl transferase. OST3/OST6 family.
Mass (Da):
39676
Number AA:
348
UniProt ID:
Q13454
International Prot ID:
IPI00013328
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0008250
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0018279
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
G
A
R
G
A
P
S
R
R
R
Q
A
G
R
Site 2
Y19
Q
A
G
R
R
L
R
Y
L
P
T
G
S
F
P
Site 3
T22
R
R
L
R
Y
L
P
T
G
S
F
P
F
L
L
Site 4
S60
V
E
Q
L
M
E
W
S
S
R
R
S
I
F
R
Site 5
S61
E
Q
L
M
E
W
S
S
R
R
S
I
F
R
M
Site 6
S64
M
E
W
S
S
R
R
S
I
F
R
M
N
G
D
Site 7
S85
K
A
P
P
R
N
Y
S
M
I
V
M
F
T
A
Site 8
S100
L
Q
P
Q
R
Q
C
S
V
C
R
Q
A
N
E
Site 9
S115
E
Y
Q
I
L
A
N
S
W
R
Y
S
S
A
F
Site 10
S119
L
A
N
S
W
R
Y
S
S
A
F
C
N
K
L
Site 11
T150
L
N
M
N
S
A
P
T
F
M
H
F
P
P
K
Site 12
T165
G
R
P
K
R
A
D
T
F
D
L
Q
R
I
G
Site 13
Y216
S
L
V
G
G
L
L
Y
L
R
R
N
N
L
E
Site 14
Y226
R
N
N
L
E
F
I
Y
N
K
T
G
W
A
M
Site 15
Y256
N
H
I
R
G
P
P
Y
A
H
K
N
P
H
N
Site 16
S267
N
P
H
N
G
Q
V
S
Y
I
H
G
S
S
Q
Site 17
Y268
P
H
N
G
Q
V
S
Y
I
H
G
S
S
Q
A
Site 18
S273
V
S
Y
I
H
G
S
S
Q
A
Q
F
V
A
E
Site 19
S281
Q
A
Q
F
V
A
E
S
H
I
I
L
V
L
N
Site 20
T292
L
V
L
N
A
A
I
T
M
G
M
V
L
L
N
Site 21
S304
L
L
N
E
A
A
T
S
K
G
D
V
G
K
R
Site 22
S327
G
L
V
V
F
F
F
S
F
L
L
S
I
F
R
Site 23
S331
F
F
F
S
F
L
L
S
I
F
R
S
K
Y
H
Site 24
Y337
L
S
I
F
R
S
K
Y
H
G
Y
P
Y
S
D
Site 25
Y340
F
R
S
K
Y
H
G
Y
P
Y
S
D
L
D
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation