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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TARBP1
Full Name:
Probable methyltransferase TARBP1
Alias:
TAR RNA-binding protein 1
Type:
Mass (Da):
181657
Number AA:
1621
UniProt ID:
Q13395
International Prot ID:
IPI00298447
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006355
GO:0006357
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
V
L
A
E
A
L
L
S
Q
S
R
D
P
R
A
Site 2
S13
A
E
A
L
L
S
Q
S
R
D
P
R
A
L
L
Site 3
T35
A
S
A
E
R
V
E
T
L
R
F
L
L
Q
R
Site 4
S51
E
D
E
E
A
R
G
S
G
G
A
G
A
L
P
Site 5
S87
P
A
G
G
P
D
P
S
L
Q
P
R
H
R
R
Site 6
S223
A
P
G
A
S
L
G
S
G
R
V
E
E
K
L
Site 7
T280
L
G
Q
A
D
A
L
T
R
K
R
A
R
Y
L
Site 8
Y286
L
T
R
K
R
A
R
Y
L
L
Q
R
A
V
E
Site 9
T303
A
E
L
G
A
D
C
T
C
G
P
Q
E
G
N
Site 10
S313
P
Q
E
G
N
G
P
S
L
F
W
W
S
E
R
Site 11
S318
G
P
S
L
F
W
W
S
E
R
K
K
D
E
L
Site 12
Y360
K
L
N
N
L
F
E
Y
A
V
S
E
E
N
G
Site 13
S392
E
S
E
N
K
I
L
S
K
E
G
V
I
H
F
Site 14
S411
E
T
K
I
L
P
F
S
P
E
F
S
E
F
I
Site 15
S427
G
P
L
M
D
A
L
S
E
S
S
L
Y
S
R
Site 16
S429
L
M
D
A
L
S
E
S
S
L
Y
S
R
S
P
Site 17
S430
M
D
A
L
S
E
S
S
L
Y
S
R
S
P
G
Site 18
Y432
A
L
S
E
S
S
L
Y
S
R
S
P
G
Q
P
Site 19
S433
L
S
E
S
S
L
Y
S
R
S
P
G
Q
P
I
Site 20
S435
E
S
S
L
Y
S
R
S
P
G
Q
P
I
G
S
Site 21
S442
S
P
G
Q
P
I
G
S
C
S
P
L
G
L
K
Site 22
S444
G
Q
P
I
G
S
C
S
P
L
G
L
K
L
Q
Site 23
S491
A
V
P
I
L
F
L
S
K
A
L
A
N
V
P
Site 24
S558
D
V
S
T
F
L
M
S
L
R
Q
E
E
S
L
Site 25
S564
M
S
L
R
Q
E
E
S
L
G
R
G
T
S
L
Site 26
T569
E
E
S
L
G
R
G
T
S
L
W
T
E
L
C
Site 27
S570
E
S
L
G
R
G
T
S
L
W
T
E
L
C
D
Site 28
S584
D
W
L
R
V
N
E
S
Y
F
K
P
S
P
T
Site 29
Y585
W
L
R
V
N
E
S
Y
F
K
P
S
P
T
C
Site 30
S589
N
E
S
Y
F
K
P
S
P
T
C
S
S
I
G
Site 31
T591
S
Y
F
K
P
S
P
T
C
S
S
I
G
L
H
Site 32
S593
F
K
P
S
P
T
C
S
S
I
G
L
H
K
T
Site 33
T600
S
S
I
G
L
H
K
T
S
L
N
A
Y
V
K
Site 34
S601
S
I
G
L
H
K
T
S
L
N
A
Y
V
K
S
Site 35
Y605
H
K
T
S
L
N
A
Y
V
K
S
I
V
Q
E
Site 36
S608
S
L
N
A
Y
V
K
S
I
V
Q
E
Y
V
K
Site 37
Y613
V
K
S
I
V
Q
E
Y
V
K
S
S
A
W
E
Site 38
S616
I
V
Q
E
Y
V
K
S
S
A
W
E
T
G
E
Site 39
T621
V
K
S
S
A
W
E
T
G
E
N
C
F
M
P
Site 40
T651
V
D
V
E
G
M
K
T
Q
Y
S
G
K
Q
R
Site 41
S654
E
G
M
K
T
Q
Y
S
G
K
Q
R
T
E
N
Site 42
Y682
M
K
F
S
T
N
A
Y
M
P
L
L
K
T
D
Site 43
S708
T
C
R
L
K
G
S
S
A
Q
D
D
E
V
S
Site 44
S724
V
L
Q
N
F
F
M
S
T
T
E
S
I
S
E
Site 45
T726
Q
N
F
F
M
S
T
T
E
S
I
S
E
F
I
Site 46
T738
E
F
I
L
R
R
L
T
M
N
E
L
N
S
V
Site 47
S744
L
T
M
N
E
L
N
S
V
S
D
L
D
R
C
Site 48
S787
I
S
L
L
K
N
A
S
I
Q
H
L
Q
E
M
Site 49
S796
Q
H
L
Q
E
M
D
S
G
Q
E
P
T
V
G
Site 50
S832
K
P
E
L
Q
L
D
S
L
H
A
G
P
L
E
Site 51
S843
G
P
L
E
S
F
L
S
S
L
Q
L
N
Q
T
Site 52
T850
S
S
L
Q
L
N
Q
T
L
Q
K
P
H
A
E
Site 53
S861
P
H
A
E
E
Q
S
S
Y
A
H
P
L
E
C
Site 54
Y862
H
A
E
E
Q
S
S
Y
A
H
P
L
E
C
S
Site 55
S870
A
H
P
L
E
C
S
S
V
L
E
E
S
S
S
Site 56
S875
C
S
S
V
L
E
E
S
S
S
S
Q
G
W
G
Site 57
S876
S
S
V
L
E
E
S
S
S
S
Q
G
W
G
K
Site 58
S877
S
V
L
E
E
S
S
S
S
Q
G
W
G
K
I
Site 59
S878
V
L
E
E
S
S
S
S
Q
G
W
G
K
I
V
Site 60
S964
K
L
L
T
S
S
E
S
L
C
I
E
S
F
D
Site 61
Y1015
A
K
I
K
G
Q
A
Y
F
K
I
K
E
I
M
Site 62
S1052
Q
S
W
I
V
S
A
S
N
V
S
Q
G
S
L
Site 63
S1058
A
S
N
V
S
Q
G
S
L
S
S
A
K
N
Y
Site 64
S1060
N
V
S
Q
G
S
L
S
S
A
K
N
Y
S
E
Site 65
S1061
V
S
Q
G
S
L
S
S
A
K
N
Y
S
E
L
Site 66
Y1065
S
L
S
S
A
K
N
Y
S
E
L
I
L
E
A
Site 67
T1077
L
E
A
C
I
F
G
T
V
F
R
R
D
Q
R
Site 68
T1091
R
L
V
Q
D
V
Q
T
F
I
E
N
L
G
H
Site 69
Y1115
N
T
K
R
E
D
H
Y
V
R
I
C
A
V
K
Site 70
S1133
L
L
D
G
S
N
M
S
H
K
L
F
I
E
D
Site 71
S1153
L
D
K
D
E
L
V
S
K
S
K
K
R
Y
Y
Site 72
S1155
K
D
E
L
V
S
K
S
K
K
R
Y
Y
V
N
Site 73
Y1159
V
S
K
S
K
K
R
Y
Y
V
N
S
L
Q
H
Site 74
Y1160
S
K
S
K
K
R
Y
Y
V
N
S
L
Q
H
R
Site 75
S1163
K
K
R
Y
Y
V
N
S
L
Q
H
R
V
K
N
Site 76
T1242
Y
G
E
E
N
L
K
T
S
I
C
T
F
L
A
Site 77
T1258
L
S
H
L
D
I
I
T
Q
N
I
P
E
K
K
Site 78
Y1289
H
N
F
S
V
R
L
Y
A
L
V
A
L
K
K
Site 79
S1325
S
S
L
H
Q
V
E
S
M
H
G
A
G
N
A
Site 80
Y1354
T
F
H
P
L
K
D
Y
C
L
E
T
I
F
Y
Site 81
S1397
A
G
F
Q
W
Y
L
S
Q
T
Q
L
S
K
L
Site 82
S1402
Y
L
S
Q
T
Q
L
S
K
L
K
P
G
D
W
Site 83
S1410
K
L
K
P
G
D
W
S
Q
Q
D
I
G
T
N
Site 84
S1442
I
P
W
N
S
R
V
S
D
L
D
L
E
L
L
Site 85
T1475
A
S
L
I
D
K
P
T
N
L
G
G
L
C
R
Site 86
S1501
V
G
S
L
Q
C
I
S
D
K
Q
F
Q
H
L
Site 87
S1509
D
K
Q
F
Q
H
L
S
V
S
A
E
Q
W
L
Site 88
S1511
Q
F
Q
H
L
S
V
S
A
E
Q
W
L
P
L
Site 89
Y1529
K
P
P
Q
L
I
D
Y
L
Q
Q
K
K
T
E
Site 90
T1535
D
Y
L
Q
Q
K
K
T
E
G
Y
T
I
I
G
Site 91
S1549
G
V
E
Q
T
A
K
S
L
D
L
T
Q
Y
C
Site 92
T1553
T
A
K
S
L
D
L
T
Q
Y
C
F
P
E
K
Site 93
Y1555
K
S
L
D
L
T
Q
Y
C
F
P
E
K
S
L
Site 94
S1561
Q
Y
C
F
P
E
K
S
L
L
L
L
G
N
E
Site 95
S1594
P
Q
Q
G
I
I
R
S
L
N
V
H
V
S
G
Site 96
S1615
Y
T
R
Q
Q
L
L
S
H
G
D
T
K
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation