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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAD2L1
Full Name:
Mitotic spindle assembly checkpoint protein MAD2A
Alias:
HSMAD2; MAD2; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2 mitotic arrest deficient-like 1; MAD2 mitotic arrest deficient-like 1 (yeast); MAD2-like 1; MAD2-like protein 1; MD2L1; Mitotic arrest deficient, yeast, homolog-like 1
Type:
Cell cycle regulation
Mass (Da):
23510
Number AA:
205
UniProt ID:
Q13257
International Prot ID:
IPI00012369
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000777
GO:0005829
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051301
GO:0051436
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
L
S
R
E
Q
G
I
T
L
R
G
S
A
E
I
Site 2
Y33
F
G
I
N
S
I
L
Y
Q
R
G
I
Y
P
S
Site 3
Y38
I
L
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
Site 4
S40
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
V
Q
Site 5
T42
R
G
I
Y
P
S
E
T
F
T
R
V
Q
K
Y
Site 6
Y64
T
D
L
E
L
I
K
Y
L
N
N
V
V
E
Q
Site 7
Y77
E
Q
L
K
D
W
L
Y
K
C
S
V
Q
K
L
Site 8
T109
F
D
I
E
C
D
K
T
A
K
D
D
S
A
P
Site 9
S114
D
K
T
A
K
D
D
S
A
P
R
E
K
S
Q
Site 10
S120
D
S
A
P
R
E
K
S
Q
K
A
I
Q
D
E
Site 11
S130
A
I
Q
D
E
I
R
S
V
I
R
Q
I
T
A
Site 12
S170
V
P
E
K
W
E
E
S
G
P
Q
F
I
T
N
Site 13
S178
G
P
Q
F
I
T
N
S
E
E
V
R
L
R
S
Site 14
S185
S
E
E
V
R
L
R
S
F
T
T
T
I
H
K
Site 15
T187
E
V
R
L
R
S
F
T
T
T
I
H
K
V
N
Site 16
T189
R
L
R
S
F
T
T
T
I
H
K
V
N
S
M
Site 17
S195
T
T
I
H
K
V
N
S
M
V
A
Y
K
I
P
Site 18
Y199
K
V
N
S
M
V
A
Y
K
I
P
V
N
D
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation