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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNAJC3
Full Name:
DnaJ homolog subfamily C member 3
Alias:
Interferon-induced, double-stranded RNA-activated protein kinase inhibitor;Protein kinase inhibitor of 58 kDa
Type:
Mass (Da):
57580
Number AA:
504
UniProt ID:
Q13217
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
V
A
P
G
S
V
T
S
R
L
G
S
Site 2
T8
M
V
A
P
G
S
V
T
S
R
L
G
S
V
F
Site 3
S9
V
A
P
G
S
V
T
S
R
L
G
S
V
F
P
Site 4
Y71
V
D
G
D
P
D
N
Y
I
A
Y
Y
R
R
A
Site 5
Y74
D
P
D
N
Y
I
A
Y
Y
R
R
A
T
V
F
Site 6
Y75
P
D
N
Y
I
A
Y
Y
R
R
A
T
V
F
L
Site 7
T95
K
A
A
L
P
D
L
T
K
V
I
Q
L
K
M
Site 8
T105
I
Q
L
K
M
D
F
T
A
A
R
L
Q
R
G
Site 9
S134
D
F
K
K
V
L
K
S
N
P
S
E
N
E
E
Site 10
S137
K
V
L
K
S
N
P
S
E
N
E
E
K
E
A
Site 11
S151
A
Q
S
Q
L
I
K
S
D
E
M
Q
R
L
R
Site 12
S159
D
E
M
Q
R
L
R
S
Q
A
L
N
A
F
G
Site 13
T222
S
K
L
K
N
D
N
T
E
A
F
Y
K
I
S
Site 14
T230
E
A
F
Y
K
I
S
T
L
Y
Y
Q
L
G
D
Site 15
Y232
F
Y
K
I
S
T
L
Y
Y
Q
L
G
D
H
E
Site 16
Y233
Y
K
I
S
T
L
Y
Y
Q
L
G
D
H
E
L
Site 17
S241
Q
L
G
D
H
E
L
S
L
S
E
V
R
E
C
Site 18
S243
G
D
H
E
L
S
L
S
E
V
R
E
C
L
K
Site 19
Y262
H
K
R
C
F
A
H
Y
K
Q
V
K
K
L
N
Site 20
Y284
E
L
I
R
D
G
R
Y
T
D
A
T
S
K
Y
Site 21
T285
L
I
R
D
G
R
Y
T
D
A
T
S
K
Y
E
Site 22
T288
D
G
R
Y
T
D
A
T
S
K
Y
E
S
V
M
Site 23
S289
G
R
Y
T
D
A
T
S
K
Y
E
S
V
M
K
Site 24
Y291
Y
T
D
A
T
S
K
Y
E
S
V
M
K
T
E
Site 25
S293
D
A
T
S
K
Y
E
S
V
M
K
T
E
P
S
Site 26
T297
K
Y
E
S
V
M
K
T
E
P
S
I
A
E
Y
Site 27
Y304
T
E
P
S
I
A
E
Y
T
V
R
S
K
E
R
Site 28
T305
E
P
S
I
A
E
Y
T
V
R
S
K
E
R
I
Site 29
S317
E
R
I
C
H
C
F
S
K
D
E
K
P
V
E
Site 30
Y350
L
K
D
R
A
E
A
Y
L
I
E
E
M
Y
D
Site 31
Y356
A
Y
L
I
E
E
M
Y
D
E
A
I
Q
D
Y
Site 32
Y363
Y
D
E
A
I
Q
D
Y
E
T
A
Q
E
H
N
Site 33
S390
A
Q
R
L
L
K
Q
S
Q
K
R
D
Y
Y
K
Site 34
Y395
K
Q
S
Q
K
R
D
Y
Y
K
I
L
G
V
K
Site 35
Y396
Q
S
Q
K
R
D
Y
Y
K
I
L
G
V
K
R
Site 36
S450
A
A
A
K
E
V
L
S
D
P
E
M
R
K
K
Site 37
S469
E
D
P
L
D
A
E
S
Q
Q
G
G
G
G
N
Site 38
S493
Q
G
F
N
P
F
S
S
G
G
P
F
R
F
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation