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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RLF
Full Name:
Zinc finger protein Rlf
Alias:
Rearranged L-myc fusion; Rearranged L-myc fusion gene protein; Zn-15 related; Zn-15L; Zn-15-related protein; ZNF292L
Type:
Transcription factor
Mass (Da):
217953
Number AA:
1914
UniProt ID:
Q13129
International Prot ID:
IPI00018294
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
G
D
G
V
E
T
E
S
M
V
R
G
H
R
P
Site 2
S41
V
R
G
H
R
P
V
S
P
A
P
G
A
S
G
Site 3
T58
P
C
L
W
Q
L
E
T
E
L
R
E
Q
E
V
Site 4
S66
E
L
R
E
Q
E
V
S
E
V
S
S
L
N
Y
Site 5
S70
Q
E
V
S
E
V
S
S
L
N
Y
C
R
S
F
Site 6
Y73
S
E
V
S
S
L
N
Y
C
R
S
F
C
Q
T
Site 7
S76
S
S
L
N
Y
C
R
S
F
C
Q
T
L
L
Q
Site 8
S86
Q
T
L
L
Q
Y
A
S
N
K
N
A
S
E
H
Site 9
Y96
N
A
S
E
H
I
V
Y
L
L
E
V
Y
R
L
Site 10
Y101
I
V
Y
L
L
E
V
Y
R
L
A
I
Q
S
F
Site 11
S107
V
Y
R
L
A
I
Q
S
F
A
S
A
R
P
Y
Site 12
S110
L
A
I
Q
S
F
A
S
A
R
P
Y
L
T
T
Site 13
Y114
S
F
A
S
A
R
P
Y
L
T
T
E
C
E
D
Site 14
T117
S
A
R
P
Y
L
T
T
E
C
E
D
V
L
L
Site 15
S132
V
L
G
R
L
V
L
S
C
F
E
L
L
L
S
Site 16
S156
V
W
L
P
F
L
Q
S
L
Q
E
S
H
D
A
Site 17
S160
F
L
Q
S
L
Q
E
S
H
D
A
L
L
E
F
Site 18
S213
L
I
A
Q
E
G
P
S
F
L
Q
M
R
I
K
Site 19
S225
R
I
K
H
L
L
K
S
N
C
I
P
Q
A
T
Site 20
S241
L
S
K
L
C
A
E
S
K
E
I
S
N
V
S
Site 21
S245
C
A
E
S
K
E
I
S
N
V
S
S
F
Q
Q
Site 22
S249
K
E
I
S
N
V
S
S
F
Q
Q
A
Y
I
T
Site 23
T294
E
S
E
G
Q
D
N
T
A
F
V
L
C
T
T
Site 24
S332
L
Q
R
R
I
D
P
S
L
D
T
F
L
E
R
Site 25
T335
R
I
D
P
S
L
D
T
F
L
E
R
C
R
Q
Site 26
S385
R
A
L
Q
L
R
S
S
E
D
E
E
M
K
A
Site 27
T415
V
R
R
A
C
Q
L
T
E
F
L
I
E
P
S
Site 28
Y433
F
N
M
L
E
E
L
Y
L
Q
P
D
Q
K
F
Site 29
S450
E
N
A
P
V
P
N
S
L
R
C
E
L
L
L
Site 30
S488
Q
L
L
G
Q
E
A
S
D
S
D
D
D
L
S
Site 31
S490
L
G
Q
E
A
S
D
S
D
D
D
L
S
G
Y
Site 32
S495
S
D
S
D
D
D
L
S
G
Y
E
M
S
I
N
Site 33
Y497
S
D
D
D
L
S
G
Y
E
M
S
I
N
D
T
Site 34
T504
Y
E
M
S
I
N
D
T
D
V
L
E
S
F
L
Site 35
S512
D
V
L
E
S
F
L
S
D
Y
D
E
G
K
E
Site 36
Y514
L
E
S
F
L
S
D
Y
D
E
G
K
E
D
K
Site 37
Y523
E
G
K
E
D
K
Q
Y
R
R
R
D
L
T
D
Site 38
T529
Q
Y
R
R
R
D
L
T
D
Q
H
K
E
K
R
Site 39
S543
R
D
K
K
P
I
G
S
S
E
R
Y
Q
R
W
Site 40
S544
D
K
K
P
I
G
S
S
E
R
Y
Q
R
W
L
Site 41
Y547
P
I
G
S
S
E
R
Y
Q
R
W
L
Q
Y
K
Site 42
S610
E
H
V
K
M
P
P
S
R
R
D
R
S
K
K
Site 43
S615
P
P
S
R
R
D
R
S
K
K
K
L
L
L
K
Site 44
S624
K
K
L
L
L
K
G
S
Q
K
G
I
C
P
K
Site 45
S632
Q
K
G
I
C
P
K
S
P
S
A
I
P
E
Q
Site 46
S634
G
I
C
P
K
S
P
S
A
I
P
E
Q
N
H
Site 47
S642
A
I
P
E
Q
N
H
S
L
N
D
Q
A
K
G
Site 48
Y654
A
K
G
E
S
H
E
Y
V
T
F
S
K
L
E
Site 49
T656
G
E
S
H
E
Y
V
T
F
S
K
L
E
D
C
Site 50
Y671
H
L
Q
D
R
D
L
Y
P
C
P
G
T
D
C
Site 51
T676
D
L
Y
P
C
P
G
T
D
C
S
R
V
F
K
Site 52
Y687
R
V
F
K
Q
F
K
Y
L
S
V
H
L
K
A
Site 53
S689
F
K
Q
F
K
Y
L
S
V
H
L
K
A
E
H
Site 54
S755
D
C
Y
A
R
F
G
S
V
N
E
L
L
N
H
Site 55
Y771
Q
K
H
D
D
L
R
Y
K
C
E
L
N
G
C
Site 56
Y789
F
S
D
L
G
Q
L
Y
H
H
E
A
Q
H
F
Site 57
Y801
Q
H
F
R
D
A
S
Y
T
C
N
F
L
G
C
Site 58
Y812
F
L
G
C
K
K
F
Y
Y
S
K
I
E
Y
Q
Site 59
Y813
L
G
C
K
K
F
Y
Y
S
K
I
E
Y
Q
N
Site 60
Y818
F
Y
Y
S
K
I
E
Y
Q
N
H
L
S
M
H
Site 61
S837
S
N
G
D
I
K
K
S
V
K
L
E
E
S
A
Site 62
T845
V
K
L
E
E
S
A
T
G
E
K
Q
D
C
I
Site 63
S864
L
L
N
Q
T
D
K
S
H
L
P
E
D
L
F
Site 64
S878
F
C
A
E
S
A
N
S
Q
I
D
T
E
T
A
Site 65
T882
S
A
N
S
Q
I
D
T
E
T
A
E
N
L
K
Site 66
S892
A
E
N
L
K
E
N
S
D
S
N
S
S
D
Q
Site 67
S894
N
L
K
E
N
S
D
S
N
S
S
D
Q
L
S
Site 68
S896
K
E
N
S
D
S
N
S
S
D
Q
L
S
H
S
Site 69
S897
E
N
S
D
S
N
S
S
D
Q
L
S
H
S
S
Site 70
S901
S
N
S
S
D
Q
L
S
H
S
S
S
A
S
M
Site 71
S903
S
S
D
Q
L
S
H
S
S
S
A
S
M
N
E
Site 72
S905
D
Q
L
S
H
S
S
S
A
S
M
N
E
E
L
Site 73
S907
L
S
H
S
S
S
A
S
M
N
E
E
L
I
D
Site 74
T915
M
N
E
E
L
I
D
T
L
D
H
S
E
T
M
Site 75
T921
D
T
L
D
H
S
E
T
M
Q
D
V
L
L
S
Site 76
S937
E
K
V
F
G
P
S
S
L
K
E
K
C
S
S
Site 77
S943
S
S
L
K
E
K
C
S
S
M
A
V
C
F
D
Site 78
S944
S
L
K
E
K
C
S
S
M
A
V
C
F
D
G
Site 79
Y965
F
D
G
C
G
S
T
Y
K
N
A
R
G
M
Q
Site 80
T990
F
K
P
K
K
I
K
T
K
D
L
F
P
S
L
Site 81
T1004
L
G
N
E
H
N
Q
T
T
E
K
L
D
A
E
Site 82
S1016
D
A
E
P
K
P
C
S
D
T
N
S
D
S
P
Site 83
T1018
E
P
K
P
C
S
D
T
N
S
D
S
P
D
E
Site 84
S1020
K
P
C
S
D
T
N
S
D
S
P
D
E
G
L
Site 85
S1022
C
S
D
T
N
S
D
S
P
D
E
G
L
D
H
Site 86
Y1042
C
K
R
E
H
Q
G
Y
S
S
E
S
S
I
C
Site 87
S1043
K
R
E
H
Q
G
Y
S
S
E
S
S
I
C
A
Site 88
S1044
R
E
H
Q
G
Y
S
S
E
S
S
I
C
A
S
Site 89
S1047
Q
G
Y
S
S
E
S
S
I
C
A
S
K
R
P
Site 90
S1051
S
E
S
S
I
C
A
S
K
R
P
C
T
E
D
Site 91
T1056
C
A
S
K
R
P
C
T
E
D
T
M
L
E
L
Site 92
T1059
K
R
P
C
T
E
D
T
M
L
E
L
L
L
R
Site 93
S1071
L
L
R
L
K
H
L
S
L
K
N
S
I
T
H
Site 94
S1075
K
H
L
S
L
K
N
S
I
T
H
G
S
F
S
Site 95
T1077
L
S
L
K
N
S
I
T
H
G
S
F
S
G
S
Site 96
S1080
K
N
S
I
T
H
G
S
F
S
G
S
L
Q
G
Site 97
S1082
S
I
T
H
G
S
F
S
G
S
L
Q
G
Y
P
Site 98
S1084
T
H
G
S
F
S
G
S
L
Q
G
Y
P
S
S
Site 99
Y1088
F
S
G
S
L
Q
G
Y
P
S
S
G
A
K
S
Site 100
S1090
G
S
L
Q
G
Y
P
S
S
G
A
K
S
L
Q
Site 101
S1091
S
L
Q
G
Y
P
S
S
G
A
K
S
L
Q
S
Site 102
S1095
Y
P
S
S
G
A
K
S
L
Q
S
V
S
S
I
Site 103
S1098
S
G
A
K
S
L
Q
S
V
S
S
I
S
D
L
Site 104
S1100
A
K
S
L
Q
S
V
S
S
I
S
D
L
N
F
Site 105
S1101
K
S
L
Q
S
V
S
S
I
S
D
L
N
F
Q
Site 106
S1116
N
Q
D
E
N
M
P
S
Q
Y
L
A
Q
L
A
Site 107
Y1136
C
E
L
Q
G
C
K
Y
E
F
V
T
R
E
A
Site 108
Y1148
R
E
A
L
L
M
H
Y
L
K
K
H
N
Y
S
Site 109
T1182
H
I
C
Q
R
S
F
T
R
K
T
H
L
R
I
Site 110
T1185
Q
R
S
F
T
R
K
T
H
L
R
I
H
Y
K
Site 111
Y1191
K
T
H
L
R
I
H
Y
K
N
K
H
Q
I
G
Site 112
S1199
K
N
K
H
Q
I
G
S
D
R
A
T
H
K
L
Site 113
T1203
Q
I
G
S
D
R
A
T
H
K
L
L
D
N
E
Site 114
S1219
C
D
H
E
G
P
C
S
V
D
R
L
K
G
D
Site 115
S1228
D
R
L
K
G
D
C
S
A
E
L
G
G
D
P
Site 116
S1236
A
E
L
G
G
D
P
S
S
N
S
E
K
P
H
Site 117
S1237
E
L
G
G
D
P
S
S
N
S
E
K
P
H
C
Site 118
S1239
G
G
D
P
S
S
N
S
E
K
P
H
C
H
P
Site 119
S1252
H
P
K
K
D
E
C
S
S
E
T
D
L
E
S
Site 120
S1253
P
K
K
D
E
C
S
S
E
T
D
L
E
S
S
Site 121
T1255
K
D
E
C
S
S
E
T
D
L
E
S
S
C
E
Site 122
S1259
S
S
E
T
D
L
E
S
S
C
E
E
T
E
S
Site 123
S1260
S
E
T
D
L
E
S
S
C
E
E
T
E
S
K
Site 124
T1264
L
E
S
S
C
E
E
T
E
S
K
T
S
D
I
Site 125
S1266
S
S
C
E
E
T
E
S
K
T
S
D
I
S
S
Site 126
T1268
C
E
E
T
E
S
K
T
S
D
I
S
S
P
I
Site 127
S1269
E
E
T
E
S
K
T
S
D
I
S
S
P
I
G
Site 128
S1272
E
S
K
T
S
D
I
S
S
P
I
G
S
H
R
Site 129
S1273
S
K
T
S
D
I
S
S
P
I
G
S
H
R
E
Site 130
S1277
D
I
S
S
P
I
G
S
H
R
E
E
Q
E
G
Site 131
S1290
E
G
R
E
G
R
G
S
R
R
T
V
A
K
G
Site 132
T1293
E
G
R
G
S
R
R
T
V
A
K
G
N
L
C
Site 133
Y1301
V
A
K
G
N
L
C
Y
I
L
N
K
Y
H
K
Site 134
T1316
P
F
H
C
I
H
K
T
C
N
S
S
F
T
N
Site 135
S1320
I
H
K
T
C
N
S
S
F
T
N
L
K
G
L
Site 136
Y1331
L
K
G
L
I
R
H
Y
R
T
V
H
Q
Y
N
Site 137
Y1337
H
Y
R
T
V
H
Q
Y
N
K
E
Q
L
C
L
Site 138
Y1366
K
K
I
F
A
C
K
Y
K
E
C
N
K
R
F
Site 139
S1384
K
A
L
A
K
H
C
S
D
S
H
N
L
D
H
Site 140
S1386
L
A
K
H
C
S
D
S
H
N
L
D
H
I
E
Site 141
S1399
I
E
E
P
K
V
L
S
E
A
G
S
A
A
R
Site 142
S1403
K
V
L
S
E
A
G
S
A
A
R
F
S
C
N
Site 143
S1408
A
G
S
A
A
R
F
S
C
N
Q
P
Q
C
P
Site 144
Y1442
E
G
E
I
H
S
D
Y
E
I
H
C
D
L
N
Site 145
T1456
N
G
C
G
Q
I
F
T
H
R
S
N
Y
S
Q
Site 146
Y1461
I
F
T
H
R
S
N
Y
S
Q
H
V
Y
Y
R
Site 147
Y1466
S
N
Y
S
Q
H
V
Y
Y
R
H
K
D
Y
Y
Site 148
Y1472
V
Y
Y
R
H
K
D
Y
Y
D
D
L
F
R
S
Site 149
Y1473
Y
Y
R
H
K
D
Y
Y
D
D
L
F
R
S
Q
Site 150
S1479
Y
Y
D
D
L
F
R
S
Q
K
V
A
N
E
R
Site 151
T1506
T
Q
G
H
E
H
Q
T
T
R
R
S
F
N
A
Site 152
T1507
Q
G
H
E
H
Q
T
T
R
R
S
F
N
A
K
Site 153
S1510
E
H
Q
T
T
R
R
S
F
N
A
K
S
K
K
Site 154
S1515
R
R
S
F
N
A
K
S
K
K
C
G
L
I
K
Site 155
S1529
K
E
K
K
A
P
I
S
F
K
T
R
A
E
A
Site 156
T1532
K
A
P
I
S
F
K
T
R
A
E
A
L
H
M
Site 157
S1565
S
V
V
K
L
E
S
S
I
V
R
H
Y
K
R
Site 158
Y1570
E
S
S
I
V
R
H
Y
K
R
T
H
Q
M
S
Site 159
T1573
I
V
R
H
Y
K
R
T
H
Q
M
S
S
A
Y
Site 160
S1577
Y
K
R
T
H
Q
M
S
S
A
Y
L
E
Q
Q
Site 161
S1604
K
I
K
E
E
P
P
S
E
A
D
P
C
I
K
Site 162
S1617
I
K
K
E
E
N
R
S
C
E
S
E
R
T
E
Site 163
S1620
E
E
N
R
S
C
E
S
E
R
T
E
H
S
H
Site 164
T1623
R
S
C
E
S
E
R
T
E
H
S
H
S
P
G
Site 165
S1626
E
S
E
R
T
E
H
S
H
S
P
G
D
S
S
Site 166
S1628
E
R
T
E
H
S
H
S
P
G
D
S
S
A
P
Site 167
S1632
H
S
H
S
P
G
D
S
S
A
P
I
Q
N
T
Site 168
S1633
S
H
S
P
G
D
S
S
A
P
I
Q
N
T
D
Site 169
T1639
S
S
A
P
I
Q
N
T
D
C
C
H
S
S
E
Site 170
S1644
Q
N
T
D
C
C
H
S
S
E
R
D
G
G
Q
Site 171
S1657
G
Q
K
G
C
I
E
S
S
S
V
F
D
A
D
Site 172
S1659
K
G
C
I
E
S
S
S
V
F
D
A
D
T
L
Site 173
T1671
D
T
L
L
Y
R
G
T
L
K
C
N
H
S
S
Site 174
S1677
G
T
L
K
C
N
H
S
S
K
T
T
S
L
E
Site 175
S1678
T
L
K
C
N
H
S
S
K
T
T
S
L
E
Q
Site 176
T1680
K
C
N
H
S
S
K
T
T
S
L
E
Q
C
N
Site 177
S1682
N
H
S
S
K
T
T
S
L
E
Q
C
N
I
V
Site 178
T1707
S
I
P
N
P
N
G
T
E
S
G
T
Y
F
T
Site 179
S1709
P
N
P
N
G
T
E
S
G
T
Y
F
T
S
F
Site 180
T1711
P
N
G
T
E
S
G
T
Y
F
T
S
F
Q
L
Site 181
Y1712
N
G
T
E
S
G
T
Y
F
T
S
F
Q
L
P
Site 182
S1715
E
S
G
T
Y
F
T
S
F
Q
L
P
L
P
R
Site 183
S1726
P
L
P
R
I
K
E
S
E
T
R
Q
H
S
S
Site 184
T1728
P
R
I
K
E
S
E
T
R
Q
H
S
S
G
Q
Site 185
S1732
E
S
E
T
R
Q
H
S
S
G
Q
E
N
T
V
Site 186
T1738
H
S
S
G
Q
E
N
T
V
K
N
P
T
H
V
Site 187
T1743
E
N
T
V
K
N
P
T
H
V
P
K
E
N
F
Site 188
S1754
K
E
N
F
R
K
H
S
Q
P
R
S
F
D
L
Site 189
S1758
R
K
H
S
Q
P
R
S
F
D
L
K
T
Y
K
Site 190
T1763
P
R
S
F
D
L
K
T
Y
K
P
M
G
F
E
Site 191
Y1764
R
S
F
D
L
K
T
Y
K
P
M
G
F
E
S
Site 192
S1772
K
P
M
G
F
E
S
S
F
L
K
F
I
Q
E
Site 193
S1793
D
F
D
D
W
E
P
S
E
H
L
T
L
S
N
Site 194
T1797
W
E
P
S
E
H
L
T
L
S
N
S
S
Q
S
Site 195
S1799
P
S
E
H
L
T
L
S
N
S
S
Q
S
S
N
Site 196
S1801
E
H
L
T
L
S
N
S
S
Q
S
S
N
D
L
Site 197
S1805
L
S
N
S
S
Q
S
S
N
D
L
T
G
N
V
Site 198
T1809
S
Q
S
S
N
D
L
T
G
N
V
V
A
N
N
Site 199
S1830
P
E
V
D
I
P
H
S
S
S
D
S
T
I
H
Site 200
S1832
V
D
I
P
H
S
S
S
D
S
T
I
H
E
N
Site 201
S1834
I
P
H
S
S
S
D
S
T
I
H
E
N
L
T
Site 202
T1835
P
H
S
S
S
D
S
T
I
H
E
N
L
T
A
Site 203
T1895
L
E
R
S
K
F
S
T
P
I
L
D
L
F
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation