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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLF10
Full Name:
Krueppel-like factor 10
Alias:
EGR-alpha; TGFB-inducible early growth response protein 1; TIEG; TIEG1; TIEG-1; Transforming growth factor-beta-inducible early growth response 1
Type:
Transcription protein, repressor. Sp1 C2H2-type zinc-finger protein family.
Mass (Da):
52555
Number AA:
480
UniProt ID:
Q13118
International Prot ID:
IPI00011863
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0007267
GO:0008285
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
L
N
F
G
A
S
L
Q
Q
T
A
E
E
Site 2
T11
F
G
A
S
L
Q
Q
T
A
E
E
R
M
E
M
Site 3
S20
E
E
R
M
E
M
I
S
E
R
P
K
E
S
M
Site 4
S26
I
S
E
R
P
K
E
S
M
Y
S
W
N
K
T
Site 5
S29
R
P
K
E
S
M
Y
S
W
N
K
T
A
E
K
Site 6
T33
S
M
Y
S
W
N
K
T
A
E
K
S
D
F
E
Site 7
S37
W
N
K
T
A
E
K
S
D
F
E
A
V
E
A
Site 8
S47
E
A
V
E
A
L
M
S
M
S
C
S
W
K
S
Site 9
S51
A
L
M
S
M
S
C
S
W
K
S
D
F
K
K
Site 10
Y59
W
K
S
D
F
K
K
Y
V
E
N
R
P
V
T
Site 11
T66
Y
V
E
N
R
P
V
T
P
V
S
D
L
S
E
Site 12
S69
N
R
P
V
T
P
V
S
D
L
S
E
E
E
N
Site 13
S72
V
T
P
V
S
D
L
S
E
E
E
N
L
L
P
Site 14
T81
E
E
N
L
L
P
G
T
P
D
F
H
T
I
P
Site 15
T93
T
I
P
A
F
C
L
T
P
P
Y
S
P
S
D
Site 16
S97
F
C
L
T
P
P
Y
S
P
S
D
F
E
P
S
Site 17
S99
L
T
P
P
Y
S
P
S
D
F
E
P
S
Q
V
Site 18
S104
S
P
S
D
F
E
P
S
Q
V
S
N
L
M
A
Site 19
S121
P
S
T
V
H
F
K
S
L
S
D
T
A
K
P
Site 20
S123
T
V
H
F
K
S
L
S
D
T
A
K
P
H
I
Site 21
T125
H
F
K
S
L
S
D
T
A
K
P
H
I
A
A
Site 22
S140
P
F
K
E
E
E
K
S
P
V
S
A
P
K
L
Site 23
S143
E
E
E
K
S
P
V
S
A
P
K
L
P
K
A
Site 24
S154
L
P
K
A
Q
A
T
S
V
I
R
H
T
A
D
Site 25
T159
A
T
S
V
I
R
H
T
A
D
A
Q
L
C
N
Site 26
Y180
K
A
A
S
I
L
N
Y
Q
N
N
S
F
R
R
Site 27
T189
N
N
S
F
R
R
R
T
H
L
N
V
E
A
A
Site 28
S206
N
I
P
C
A
A
V
S
P
N
R
S
K
C
E
Site 29
S210
A
A
V
S
P
N
R
S
K
C
E
R
N
T
V
Site 30
T216
R
S
K
C
E
R
N
T
V
A
D
V
D
E
K
Site 31
Y229
E
K
A
S
A
A
L
Y
D
F
S
V
P
S
S
Site 32
S236
Y
D
F
S
V
P
S
S
E
T
V
I
C
R
S
Site 33
T238
F
S
V
P
S
S
E
T
V
I
C
R
S
Q
P
Site 34
S243
S
E
T
V
I
C
R
S
Q
P
A
P
V
S
P
Site 35
S249
R
S
Q
P
A
P
V
S
P
Q
Q
K
S
V
L
Site 36
S254
P
V
S
P
Q
Q
K
S
V
L
V
S
P
P
A
Site 37
S292
V
V
T
T
V
V
P
S
T
P
P
S
Q
P
P
Site 38
T293
V
T
T
V
V
P
S
T
P
P
S
Q
P
P
A
Site 39
S296
V
V
P
S
T
P
P
S
Q
P
P
A
V
C
P
Site 40
S329
P
Q
P
V
V
Q
S
S
K
P
P
V
V
S
P
Site 41
S335
S
S
K
P
P
V
V
S
P
N
G
T
R
L
S
Site 42
T339
P
V
V
S
P
N
G
T
R
L
S
P
I
A
P
Site 43
S342
S
P
N
G
T
R
L
S
P
I
A
P
A
P
G
Site 44
S351
I
A
P
A
P
G
F
S
P
S
A
A
K
V
T
Site 45
S353
P
A
P
G
F
S
P
S
A
A
K
V
T
P
Q
Site 46
T358
S
P
S
A
A
K
V
T
P
Q
I
D
S
S
R
Site 47
S363
K
V
T
P
Q
I
D
S
S
R
I
R
S
H
I
Site 48
S364
V
T
P
Q
I
D
S
S
R
I
R
S
H
I
C
Site 49
S368
I
D
S
S
R
I
R
S
H
I
C
S
H
P
G
Site 50
S372
R
I
R
S
H
I
C
S
H
P
G
C
G
K
T
Site 51
T379
S
H
P
G
C
G
K
T
Y
F
K
S
S
H
L
Site 52
Y380
H
P
G
C
G
K
T
Y
F
K
S
S
H
L
K
Site 53
S383
C
G
K
T
Y
F
K
S
S
H
L
K
A
H
T
Site 54
S384
G
K
T
Y
F
K
S
S
H
L
K
A
H
T
R
Site 55
T392
H
L
K
A
H
T
R
T
H
T
G
E
K
P
F
Site 56
T394
K
A
H
T
R
T
H
T
G
E
K
P
F
S
C
Site 57
S413
C
E
R
R
F
A
R
S
D
E
L
S
R
H
R
Site 58
S417
F
A
R
S
D
E
L
S
R
H
R
R
T
H
T
Site 59
T422
E
L
S
R
H
R
R
T
H
T
G
E
K
K
F
Site 60
T424
S
R
H
R
R
T
H
T
G
E
K
K
F
A
C
Site 61
T445
F
M
R
S
D
H
L
T
K
H
A
R
R
H
L
Site 62
S453
K
H
A
R
R
H
L
S
A
K
K
L
P
N
W
Site 63
T475
N
D
I
A
L
P
P
T
P
A
P
T
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation