PhosphoNET

           
Protein Info 
   
Short Name:  MKRN3
Full Name:  Probable E3 ubiquitin-protein ligase makorin-3
Alias:  D15S9; RING finger protein 63; RNF63; ZFP127; Zinc finger protein 127; ZNF127
Type:  Ribonucleoprotein complex protein
Mass (Da):  55645
Number AA:  507
UniProt ID:  Q13064
International Prot ID:  IPI00024229
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030529     Uniprot OncoNet
Molecular Function:  GO:0003676  GO:0005515  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S38DLPVCEPSGESAAPD
Site 2S41VCEPSGESAAPDSAL
Site 3S46GESAAPDSALPHAAR
Site 4S78GLRPAPASGGGAWPS
Site 5S85SGGGAWPSPLPSRSS
Site 6S89AWPSPLPSRSSGIWT
Site 7S91PSPLPSRSSGIWTKQ
Site 8S92SPLPSRSSGIWTKQI
Site 9T96SRSSGIWTKQIICRY
Site 10Y117KEGENCRYSHDLSGR
Site 11S118EGENCRYSHDLSGRK
Site 12S122CRYSHDLSGRKMATE
Site 13S133MATEGGVSPPGASAG
Site 14S138GVSPPGASAGGGPST
Site 15T145SAGGGPSTAAHIEPP
Site 16S219YRGRWVASAPEAPLQ
Site 17S228PEAPLQSSETERKQM
Site 18T230APLQSSETERKQMAV
Site 19S300HEKDMELSFAVQRGM
Site 20Y319GICMEVVYEKANPND
Site 21S349RCIRRWRSARQFENR
Site 22S368CPQCRVTSELVIPSE
Site 23S396QQYKEAMSNKACRYF
Site 24Y402MSNKACRYFAEGRGN
Site 25Y418PFGDTCFYKHEYPEG
Site 26Y422TCFYKHEYPEGWGDE
Site 27S437PPGPGGGSFSAYWHQ
Site 28S439GPGGGSFSAYWHQLV
Site 29Y441GGGSFSAYWHQLVEP
Site 30Y458MGEGNMLYKSIKKEL
Site 31S460EGNMLYKSIKKELVV
Site 32S488LRDELPFSEDQWDLL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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