KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GRIK3
Full Name:
Glutamate receptor, ionotropic kainate 3
Alias:
EAA5; Excitatory amino acid receptor 5; GLR7; GLUR7; GluR-7; GluR7a; Glutamate receptor 7
Type:
Mass (Da):
104032
Number AA:
919
UniProt ID:
Q13003
International Prot ID:
IPI00011397
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0032839
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0001640
GO:0005234
GO:0015277
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0007216
GO:0051967
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
A
P
W
R
R
L
R
Site 2
Y44
R
I
G
G
I
F
E
Y
A
D
G
P
N
A
Q
Site 3
T72
N
I
I
N
R
N
R
T
L
L
P
N
T
T
L
Site 4
T80
L
L
P
N
T
T
L
T
Y
D
I
Q
R
I
H
Site 5
Y81
L
P
N
T
T
L
T
Y
D
I
Q
R
I
H
F
Site 6
S91
Q
R
I
H
F
H
D
S
F
E
A
T
K
K
A
Site 7
T118
G
P
S
Q
G
S
C
T
N
A
V
Q
S
I
C
Site 8
Y149
L
D
N
K
D
T
F
Y
V
N
L
Y
P
D
Y
Site 9
Y153
D
T
F
Y
V
N
L
Y
P
D
Y
A
S
L
S
Site 10
S158
N
L
Y
P
D
Y
A
S
L
S
H
A
I
L
D
Site 11
T176
Y
L
K
W
R
S
A
T
V
V
Y
D
D
S
T
Site 12
T183
T
V
V
Y
D
D
S
T
G
L
I
R
L
Q
E
Site 13
S211
I
R
Q
L
P
I
D
S
D
D
S
R
P
L
L
Site 14
S214
L
P
I
D
S
D
D
S
R
P
L
L
K
E
M
Site 15
S234
F
R
I
I
F
D
C
S
H
T
M
A
A
Q
I
Site 16
T236
I
I
F
D
C
S
H
T
M
A
A
Q
I
L
K
Site 17
Y272
Y
A
L
D
L
E
P
Y
R
Y
S
G
V
N
L
Site 18
Y274
L
D
L
E
P
Y
R
Y
S
G
V
N
L
T
G
Site 19
S275
D
L
E
P
Y
R
Y
S
G
V
N
L
T
G
F
Site 20
S310
R
L
Q
A
A
P
R
S
E
S
G
L
L
D
G
Site 21
S312
Q
A
A
P
R
S
E
S
G
L
L
D
G
V
M
Site 22
S384
R
I
V
F
N
K
T
S
G
L
R
T
D
F
D
Site 23
T388
N
K
T
S
G
L
R
T
D
F
D
L
D
I
I
Site 24
S396
D
F
D
L
D
I
I
S
L
K
E
D
G
L
E
Site 25
T417
P
A
D
G
L
N
I
T
E
V
A
K
G
R
G
Site 26
T428
K
G
R
G
P
N
V
T
D
S
L
T
N
R
S
Site 27
S430
R
G
P
N
V
T
D
S
L
T
N
R
S
L
I
Site 28
T432
P
N
V
T
D
S
L
T
N
R
S
L
I
V
T
Site 29
S452
P
F
V
M
F
R
K
S
D
R
T
L
Y
G
N
Site 30
T455
M
F
R
K
S
D
R
T
L
Y
G
N
D
R
F
Site 31
Y457
R
K
S
D
R
T
L
Y
G
N
D
R
F
E
G
Site 32
Y465
G
N
D
R
F
E
G
Y
C
I
D
L
L
K
E
Site 33
Y491
R
L
V
E
D
G
K
Y
G
A
Q
D
D
K
G
Site 34
S532
R
E
K
A
I
D
F
S
K
P
F
M
T
L
G
Site 35
Y544
T
L
G
V
S
I
L
Y
R
K
P
N
G
T
N
Site 36
T550
L
Y
R
K
P
N
G
T
N
P
S
V
F
S
F
Site 37
S553
K
P
N
G
T
N
P
S
V
F
S
F
L
N
P
Site 38
S556
G
T
N
P
S
V
F
S
F
L
N
P
L
S
P
Site 39
Y592
R
F
S
P
Y
E
W
Y
D
A
H
P
C
N
P
Site 40
S620
S
F
W
F
G
M
G
S
L
M
Q
Q
G
S
E
Site 41
S626
G
S
L
M
Q
Q
G
S
E
L
M
P
K
A
L
Site 42
S668
L
T
V
E
R
M
E
S
P
I
D
S
A
D
D
Site 43
S672
R
M
E
S
P
I
D
S
A
D
D
L
A
K
Q
Site 44
Y684
A
K
Q
T
K
I
E
Y
G
A
V
K
D
G
A
Site 45
T692
G
A
V
K
D
G
A
T
M
T
F
F
K
K
S
Site 46
T694
V
K
D
G
A
T
M
T
F
F
K
K
S
K
I
Site 47
S699
T
M
T
F
F
K
K
S
K
I
S
T
F
E
K
Site 48
T703
F
K
K
S
K
I
S
T
F
E
K
M
W
A
F
Site 49
S712
E
K
M
W
A
F
M
S
S
K
P
S
A
L
V
Site 50
S716
A
F
M
S
S
K
P
S
A
L
V
K
N
N
E
Site 51
Y734
Q
R
A
L
T
A
D
Y
A
L
L
M
E
S
T
Site 52
Y745
M
E
S
T
T
I
E
Y
V
T
Q
R
N
C
N
Site 53
T747
S
T
T
I
E
Y
V
T
Q
R
N
C
N
L
T
Site 54
T754
T
Q
R
N
C
N
L
T
Q
I
G
G
L
I
D
Site 55
T769
S
K
G
Y
G
I
G
T
P
M
G
S
P
Y
R
Site 56
S773
G
I
G
T
P
M
G
S
P
Y
R
D
K
I
T
Site 57
T780
S
P
Y
R
D
K
I
T
I
A
I
L
Q
L
Q
Site 58
S803
K
E
K
W
W
R
G
S
G
C
P
E
E
E
N
Site 59
T850
F
V
Y
K
L
R
K
T
A
E
R
E
Q
R
S
Site 60
S857
T
A
E
R
E
Q
R
S
F
C
S
T
V
A
D
Site 61
T861
E
Q
R
S
F
C
S
T
V
A
D
E
I
R
F
Site 62
S869
V
A
D
E
I
R
F
S
L
T
C
Q
R
R
V
Site 63
T871
D
E
I
R
F
S
L
T
C
Q
R
R
V
K
H
Site 64
S907
R
R
L
P
G
K
D
S
M
A
C
S
T
S
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation