KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FOXF1
Full Name:
Forkhead box protein F1
Alias:
Forkhead-related activator 1;Forkhead-related protein FKHL5;Forkhead-related transcription factor 1
Type:
Mass (Da):
40122
Number AA:
379
UniProt ID:
Q12946
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
G
A
A
M
D
P
A
S
S
G
P
S
K
A
K
Site 2
S31
A
A
M
D
P
A
S
S
G
P
S
K
A
K
K
Site 3
S34
D
P
A
S
S
G
P
S
K
A
K
K
T
N
A
Site 4
T39
G
P
S
K
A
K
K
T
N
A
G
I
R
R
P
Site 5
Y51
R
R
P
E
K
P
P
Y
S
Y
I
A
L
I
V
Site 6
S52
R
P
E
K
P
P
Y
S
Y
I
A
L
I
V
M
Site 7
T70
S
S
P
T
K
R
L
T
L
S
E
I
Y
Q
F
Site 8
S72
P
T
K
R
L
T
L
S
E
I
Y
Q
F
L
Q
Site 9
Y89
F
P
F
F
R
G
S
Y
Q
G
W
K
N
S
V
Site 10
S95
S
Y
Q
G
W
K
N
S
V
R
H
N
L
S
L
Site 11
S101
N
S
V
R
H
N
L
S
L
N
E
C
F
I
K
Site 12
Y121
G
R
P
G
K
G
H
Y
W
T
I
D
P
A
S
Site 13
T123
P
G
K
G
H
Y
W
T
I
D
P
A
S
E
F
Site 14
S136
E
F
M
F
E
E
G
S
F
R
R
R
P
R
G
Site 15
Y155
C
Q
A
L
K
P
M
Y
S
M
M
N
G
L
G
Site 16
T169
G
F
N
H
L
P
D
T
Y
G
F
Q
G
S
A
Site 17
Y170
F
N
H
L
P
D
T
Y
G
F
Q
G
S
A
G
Site 18
S175
D
T
Y
G
F
Q
G
S
A
G
G
L
S
C
P
Site 19
S180
Q
G
S
A
G
G
L
S
C
P
P
N
S
L
A
Site 20
S212
G
M
A
L
P
S
H
S
V
P
H
L
P
S
N
Site 21
S218
H
S
V
P
H
L
P
S
N
G
G
H
S
Y
M
Site 22
S223
L
P
S
N
G
G
H
S
Y
M
G
G
C
G
G
Site 23
Y224
P
S
N
G
G
H
S
Y
M
G
G
C
G
G
A
Site 24
Y236
G
G
A
A
A
G
E
Y
P
H
H
D
S
S
V
Site 25
S241
G
E
Y
P
H
H
D
S
S
V
P
A
S
P
L
Site 26
S242
E
Y
P
H
H
D
S
S
V
P
A
S
P
L
L
Site 27
S246
H
D
S
S
V
P
A
S
P
L
L
P
T
G
A
Site 28
S264
M
E
P
H
A
V
Y
S
G
S
A
A
A
W
P
Site 29
S280
S
A
S
A
A
L
N
S
G
A
S
Y
I
K
Q
Site 30
Y284
A
L
N
S
G
A
S
Y
I
K
Q
Q
P
L
S
Site 31
S291
Y
I
K
Q
Q
P
L
S
P
C
N
P
A
A
N
Site 32
S301
N
P
A
A
N
P
L
S
G
S
L
S
T
H
S
Site 33
S303
A
A
N
P
L
S
G
S
L
S
T
H
S
L
E
Site 34
S305
N
P
L
S
G
S
L
S
T
H
S
L
E
Q
P
Site 35
S308
S
G
S
L
S
T
H
S
L
E
Q
P
Y
L
H
Site 36
Y313
T
H
S
L
E
Q
P
Y
L
H
Q
N
S
H
N
Site 37
Y331
E
L
Q
G
I
P
R
Y
H
S
Q
S
P
S
M
Site 38
S333
Q
G
I
P
R
Y
H
S
Q
S
P
S
M
C
D
Site 39
S335
I
P
R
Y
H
S
Q
S
P
S
M
C
D
R
K
Site 40
S337
R
Y
H
S
Q
S
P
S
M
C
D
R
K
E
F
Site 41
S347
D
R
K
E
F
V
F
S
F
N
A
M
A
S
S
Site 42
S353
F
S
F
N
A
M
A
S
S
S
M
H
S
A
G
Site 43
S354
S
F
N
A
M
A
S
S
S
M
H
S
A
G
G
Site 44
S355
F
N
A
M
A
S
S
S
M
H
S
A
G
G
G
Site 45
S358
M
A
S
S
S
M
H
S
A
G
G
G
S
Y
Y
Site 46
Y365
S
A
G
G
G
S
Y
Y
H
Q
Q
V
T
Y
Q
Site 47
Y371
Y
Y
H
Q
Q
V
T
Y
Q
D
I
K
P
C
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation