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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SF3A3
Full Name:
Splicing factor 3A subunit 3
Alias:
PRP9; PRPF9; SAP 61; SAP61; SF3a60; Splicing factor 3a, subunit 3, 60kDa
Type:
RNA binding protein
Mass (Da):
58849
Number AA:
501
UniProt ID:
Q12874
International Prot ID:
IPI00029764
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016607
GO:0005681
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0000389
GO:0000377
GO:0000389
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
I
L
E
Q
Q
R
R
Y
H
E
E
K
E
R
L
Site 2
S31
K
E
M
L
T
K
K
S
T
L
R
D
Q
I
N
Site 3
T32
E
M
L
T
K
K
S
T
L
R
D
Q
I
N
S
Site 4
S39
T
L
R
D
Q
I
N
S
D
H
R
T
R
A
M
Site 5
T43
Q
I
N
S
D
H
R
T
R
A
M
Q
D
R
Y
Site 6
Y50
T
R
A
M
Q
D
R
Y
M
E
V
S
G
N
L
Site 7
S54
Q
D
R
Y
M
E
V
S
G
N
L
R
D
L
Y
Site 8
Y61
S
G
N
L
R
D
L
Y
D
D
K
D
G
L
R
Site 9
Y85
P
N
E
F
A
E
F
Y
N
R
L
K
Q
I
K
Site 10
Y136
E
F
T
D
E
E
G
Y
G
R
Y
L
D
L
H
Site 11
Y139
D
E
E
G
Y
G
R
Y
L
D
L
H
D
C
Y
Site 12
Y146
Y
L
D
L
H
D
C
Y
L
K
Y
I
N
L
K
Site 13
Y149
L
H
D
C
Y
L
K
Y
I
N
L
K
A
S
E
Site 14
Y160
K
A
S
E
K
L
D
Y
I
T
Y
L
S
I
F
Site 15
T162
S
E
K
L
D
Y
I
T
Y
L
S
I
F
D
Q
Site 16
Y163
E
K
L
D
Y
I
T
Y
L
S
I
F
D
Q
L
Site 17
Y182
K
E
R
K
N
A
E
Y
K
R
Y
L
E
M
L
Site 18
Y185
K
N
A
E
Y
K
R
Y
L
E
M
L
L
E
Y
Site 19
Y192
Y
L
E
M
L
L
E
Y
L
Q
D
Y
T
D
R
Site 20
Y196
L
L
E
Y
L
Q
D
Y
T
D
R
V
K
P
L
Site 21
T197
L
E
Y
L
Q
D
Y
T
D
R
V
K
P
L
Q
Site 22
T225
E
K
K
W
E
N
G
T
F
P
G
W
P
K
E
Site 23
S234
P
G
W
P
K
E
T
S
S
A
L
T
H
A
G
Site 24
T238
K
E
T
S
S
A
L
T
H
A
G
A
H
L
D
Site 25
S247
A
G
A
H
L
D
L
S
A
F
S
S
W
E
E
Site 26
S257
S
S
W
E
E
L
A
S
L
G
L
D
R
L
K
Site 27
T277
L
G
L
K
C
G
G
T
L
E
E
R
A
Q
R
Site 28
S287
E
R
A
Q
R
L
F
S
T
K
G
K
S
L
E
Site 29
T288
R
A
Q
R
L
F
S
T
K
G
K
S
L
E
S
Site 30
S292
L
F
S
T
K
G
K
S
L
E
S
L
D
T
S
Site 31
S295
T
K
G
K
S
L
E
S
L
D
T
S
L
F
A
Site 32
T298
K
S
L
E
S
L
D
T
S
L
F
A
K
N
P
Site 33
S299
S
L
E
S
L
D
T
S
L
F
A
K
N
P
K
Site 34
S307
L
F
A
K
N
P
K
S
K
G
T
K
R
D
T
Site 35
T314
S
K
G
T
K
R
D
T
E
R
N
K
D
I
A
Site 36
Y330
L
E
A
Q
I
Y
E
Y
V
E
I
L
G
E
Q
Site 37
T341
L
G
E
Q
R
H
L
T
H
E
N
V
Q
R
K
Site 38
T352
V
Q
R
K
Q
A
R
T
G
E
E
R
E
E
E
Site 39
S365
E
E
E
E
E
Q
I
S
E
S
E
S
E
D
E
Site 40
S367
E
E
E
Q
I
S
E
S
E
S
E
D
E
E
N
Site 41
S369
E
Q
I
S
E
S
E
S
E
D
E
E
N
E
I
Site 42
Y378
D
E
E
N
E
I
I
Y
N
P
K
N
L
P
L
Site 43
Y394
W
D
G
K
P
I
P
Y
W
L
Y
K
L
H
G
Site 44
Y397
K
P
I
P
Y
W
L
Y
K
L
H
G
L
N
I
Site 45
Y406
L
H
G
L
N
I
N
Y
N
C
E
I
C
G
N
Site 46
Y414
N
C
E
I
C
G
N
Y
T
Y
R
G
P
K
A
Site 47
Y416
E
I
C
G
N
Y
T
Y
R
G
P
K
A
F
Q
Site 48
S468
K
L
K
L
Q
K
A
S
E
R
W
Q
P
D
T
Site 49
T475
S
E
R
W
Q
P
D
T
E
E
E
Y
E
D
S
Site 50
Y479
Q
P
D
T
E
E
E
Y
E
D
S
S
G
N
V
Site 51
S482
T
E
E
E
Y
E
D
S
S
G
N
V
V
N
K
Site 52
S483
E
E
E
Y
E
D
S
S
G
N
V
V
N
K
K
Site 53
T491
G
N
V
V
N
K
K
T
Y
E
D
L
K
R
Q
Site 54
Y492
N
V
V
N
K
K
T
Y
E
D
L
K
R
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation