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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STX4
Full Name:
Syntaxin-4
Alias:
P35-2; Renal carcinoma antigen NY-REN-31; STX4A; Syntaxin 4
Type:
Vesicle protein
Mass (Da):
34180
Number AA:
297
UniProt ID:
Q12846
International Prot ID:
IPI00029730
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016323
GO:0009986
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005484
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0006892
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
L
R
Q
G
D
D
S
S
D
E
E
D
K
E
Site 2
S15
L
R
Q
G
D
D
S
S
D
E
E
D
K
E
R
Site 3
S36
P
G
T
A
R
L
G
S
P
D
E
E
F
F
H
Site 4
T47
E
F
F
H
K
V
R
T
I
R
Q
T
I
V
K
Site 5
T51
K
V
R
T
I
R
Q
T
I
V
K
L
G
N
K
Site 6
T72
Q
Q
V
T
I
L
A
T
P
L
P
E
E
S
M
Site 7
Y115
K
E
E
A
D
E
N
Y
N
S
V
N
T
R
M
Site 8
S117
E
A
D
E
N
Y
N
S
V
N
T
R
M
R
K
Site 9
T125
V
N
T
R
M
R
K
T
Q
H
G
V
L
S
Q
Site 10
S131
K
T
Q
H
G
V
L
S
Q
Q
F
V
E
L
I
Site 11
T163
I
R
R
Q
L
K
I
T
N
A
G
M
V
S
D
Site 12
S179
E
L
E
Q
M
L
D
S
G
Q
S
E
V
F
V
Site 13
S182
Q
M
L
D
S
G
Q
S
E
V
F
V
S
N
I
Site 14
T193
V
S
N
I
L
K
D
T
Q
V
T
R
Q
A
L
Site 15
S204
R
Q
A
L
N
E
I
S
A
R
H
S
E
I
Q
Site 16
S208
N
E
I
S
A
R
H
S
E
I
Q
Q
L
E
R
Site 17
S216
E
I
Q
Q
L
E
R
S
I
R
E
L
H
D
I
Site 18
S247
R
I
E
K
N
I
L
S
S
A
D
Y
V
E
R
Site 19
S248
I
E
K
N
I
L
S
S
A
D
Y
V
E
R
G
Site 20
Y251
N
I
L
S
S
A
D
Y
V
E
R
G
Q
E
H
Site 21
T261
R
G
Q
E
H
V
K
T
A
L
E
N
Q
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation