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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cdc20
Full Name:
Cell division cycle protein 20 homolog
Alias:
p55CDC
Type:
Mass (Da):
54723
Number AA:
499
UniProt ID:
Q12834
International Prot ID:
IPI00329526
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005654
GO:0005819
Uniprot
OncoNet
Molecular Function:
GO:0008022
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051301
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
A
F
E
S
D
L
H
S
L
L
Q
L
D
A
P
Site 2
S41
E
A
A
G
P
A
P
S
P
M
R
A
A
N
R
Site 3
S49
P
M
R
A
A
N
R
S
H
S
A
G
R
T
P
Site 4
S51
R
A
A
N
R
S
H
S
A
G
R
T
P
G
R
Site 5
T55
R
S
H
S
A
G
R
T
P
G
R
T
P
G
K
Site 6
T59
A
G
R
T
P
G
R
T
P
G
K
S
S
S
K
Site 7
S63
P
G
R
T
P
G
K
S
S
S
K
V
Q
T
T
Site 8
S65
R
T
P
G
K
S
S
S
K
V
Q
T
T
P
S
Site 9
T69
K
S
S
S
K
V
Q
T
T
P
S
K
P
G
G
Site 10
T70
S
S
S
K
V
Q
T
T
P
S
K
P
G
G
D
Site 11
S72
S
K
V
Q
T
T
P
S
K
P
G
G
D
R
Y
Site 12
Y79
S
K
P
G
G
D
R
Y
I
P
H
R
S
A
A
Site 13
S92
A
A
Q
M
E
V
A
S
F
L
L
S
K
E
N
Site 14
S96
E
V
A
S
F
L
L
S
K
E
N
Q
P
E
N
Site 15
S104
K
E
N
Q
P
E
N
S
Q
T
P
T
K
K
E
Site 16
T106
N
Q
P
E
N
S
Q
T
P
T
K
K
E
H
Q
Site 17
S134
E
A
K
I
L
R
L
S
G
K
P
Q
N
A
P
Site 18
Y152
Q
N
R
L
K
V
L
Y
S
Q
K
A
T
P
G
Site 19
S153
N
R
L
K
V
L
Y
S
Q
K
A
T
P
G
S
Site 20
T157
V
L
Y
S
Q
K
A
T
P
G
S
S
R
K
T
Site 21
S160
S
Q
K
A
T
P
G
S
S
R
K
T
C
R
Y
Site 22
S161
Q
K
A
T
P
G
S
S
R
K
T
C
R
Y
I
Site 23
T164
T
P
G
S
S
R
K
T
C
R
Y
I
P
S
L
Site 24
Y167
S
S
R
K
T
C
R
Y
I
P
S
L
P
D
R
Site 25
S170
K
T
C
R
Y
I
P
S
L
P
D
R
I
L
D
Site 26
Y185
A
P
E
I
R
N
D
Y
Y
L
N
L
V
D
W
Site 27
Y186
P
E
I
R
N
D
Y
Y
L
N
L
V
D
W
S
Site 28
S210
D
N
S
V
Y
L
W
S
A
S
S
G
D
I
L
Site 29
S231
Q
P
G
E
Y
I
S
S
V
A
W
I
K
E
G
Site 30
Y240
A
W
I
K
E
G
N
Y
L
A
V
G
T
S
S
Site 31
T265
Q
K
R
L
R
N
M
T
S
H
S
A
R
V
G
Site 32
S266
K
R
L
R
N
M
T
S
H
S
A
R
V
G
S
Site 33
S268
L
R
N
M
T
S
H
S
A
R
V
G
S
L
S
Site 34
S273
S
H
S
A
R
V
G
S
L
S
W
N
S
Y
I
Site 35
S275
S
A
R
V
G
S
L
S
W
N
S
Y
I
L
S
Site 36
S278
V
G
S
L
S
W
N
S
Y
I
L
S
S
G
S
Site 37
Y279
G
S
L
S
W
N
S
Y
I
L
S
S
G
S
R
Site 38
S282
S
W
N
S
Y
I
L
S
S
G
S
R
S
G
H
Site 39
S283
W
N
S
Y
I
L
S
S
G
S
R
S
G
H
I
Site 40
S285
S
Y
I
L
S
S
G
S
R
S
G
H
I
H
H
Site 41
S287
I
L
S
S
G
S
R
S
G
H
I
H
H
H
D
Site 42
S306
E
H
H
V
A
T
L
S
G
H
S
Q
E
V
C
Site 43
S338
N
L
V
N
V
W
P
S
A
P
G
E
G
G
W
Site 44
T350
G
G
W
V
P
L
Q
T
F
T
Q
H
Q
G
A
Site 45
S378
L
A
T
G
G
G
T
S
D
R
H
I
R
I
W
Site 46
Y411
S
I
L
W
S
P
H
Y
K
E
L
I
S
G
H
Site 47
S444
A
E
L
K
G
H
T
S
R
V
L
S
L
T
M
Site 48
S448
G
H
T
S
R
V
L
S
L
T
M
S
P
D
G
Site 49
T450
T
S
R
V
L
S
L
T
M
S
P
D
G
A
T
Site 50
S452
R
V
L
S
L
T
M
S
P
D
G
A
T
V
A
Site 51
T457
T
M
S
P
D
G
A
T
V
A
S
A
A
A
D
Site 52
T466
A
S
A
A
A
D
E
T
L
R
L
W
R
C
F
Site 53
S487
R
R
E
R
E
K
A
S
A
A
K
S
S
L
I
Site 54
S491
E
K
A
S
A
A
K
S
S
L
I
H
Q
G
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation