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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TROAP
Full Name:
Tastin
Alias:
Tastin; Trophinin-assisting protein
Type:
Mass (Da):
83839
Number AA:
778
UniProt ID:
Q12815
International Prot ID:
IPI00029680
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0009987
GO:0022610
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
T
T
R
Q
A
T
K
D
P
L
L
R
G
Site 2
S16
D
P
L
L
R
G
V
S
P
T
P
S
K
I
P
Site 3
T18
L
L
R
G
V
S
P
T
P
S
K
I
P
V
R
Site 4
S20
R
G
V
S
P
T
P
S
K
I
P
V
R
S
Q
Site 5
S26
P
S
K
I
P
V
R
S
Q
K
R
T
P
F
P
Site 6
T30
P
V
R
S
Q
K
R
T
P
F
P
T
V
T
S
Site 7
T34
Q
K
R
T
P
F
P
T
V
T
S
C
A
V
D
Site 8
S65
I
Q
R
P
L
V
D
S
A
G
P
R
P
K
A
Site 9
T78
K
A
R
H
Q
A
E
T
S
Q
R
L
V
G
I
Site 10
S79
A
R
H
Q
A
E
T
S
Q
R
L
V
G
I
S
Site 11
S86
S
Q
R
L
V
G
I
S
Q
P
R
N
P
L
E
Site 12
S98
P
L
E
E
L
R
P
S
P
R
G
Q
N
V
G
Site 13
T112
G
P
G
P
P
A
Q
T
E
A
P
G
T
I
E
Site 14
T117
A
Q
T
E
A
P
G
T
I
E
F
V
A
D
P
Site 15
S138
L
S
G
E
G
V
K
S
C
H
L
G
R
Q
P
Site 16
S156
K
R
V
L
V
R
G
S
Q
G
G
T
T
Q
R
Site 17
T160
V
R
G
S
Q
G
G
T
T
Q
R
V
Q
G
V
Site 18
T161
R
G
S
Q
G
G
T
T
Q
R
V
Q
G
V
R
Site 19
S170
R
V
Q
G
V
R
A
S
A
Y
L
A
P
R
T
Site 20
Y172
Q
G
V
R
A
S
A
Y
L
A
P
R
T
P
T
Site 21
T177
S
A
Y
L
A
P
R
T
P
T
H
R
L
D
P
Site 22
T179
Y
L
A
P
R
T
P
T
H
R
L
D
P
A
R
Site 23
S188
R
L
D
P
A
R
A
S
C
F
S
R
L
E
G
Site 24
S191
P
A
R
A
S
C
F
S
R
L
E
G
P
G
P
Site 25
T202
G
P
G
P
R
G
R
T
L
C
P
Q
R
L
Q
Site 26
S213
Q
R
L
Q
A
L
I
S
P
S
G
P
S
F
H
Site 27
S215
L
Q
A
L
I
S
P
S
G
P
S
F
H
P
S
Site 28
S218
L
I
S
P
S
G
P
S
F
H
P
S
T
R
P
Site 29
S222
S
G
P
S
F
H
P
S
T
R
P
S
F
Q
E
Site 30
T223
G
P
S
F
H
P
S
T
R
P
S
F
Q
E
L
Site 31
S226
F
H
P
S
T
R
P
S
F
Q
E
L
R
R
E
Site 32
T234
F
Q
E
L
R
R
E
T
A
G
S
S
R
T
S
Site 33
S237
L
R
R
E
T
A
G
S
S
R
T
S
V
S
Q
Site 34
S238
R
R
E
T
A
G
S
S
R
T
S
V
S
Q
A
Site 35
S241
T
A
G
S
S
R
T
S
V
S
Q
A
S
G
L
Site 36
S243
G
S
S
R
T
S
V
S
Q
A
S
G
L
L
L
Site 37
S259
T
P
V
Q
P
A
F
S
L
P
K
G
E
R
E
Site 38
T269
K
G
E
R
E
V
V
T
H
S
D
E
G
G
V
Site 39
S271
E
R
E
V
V
T
H
S
D
E
G
G
V
A
S
Site 40
S278
S
D
E
G
G
V
A
S
L
G
L
A
Q
R
V
Site 41
S294
L
R
E
N
R
E
M
S
H
T
R
D
S
H
D
Site 42
T296
E
N
R
E
M
S
H
T
R
D
S
H
D
S
H
Site 43
S299
E
M
S
H
T
R
D
S
H
D
S
H
L
M
P
Site 44
S302
H
T
R
D
S
H
D
S
H
L
M
P
S
P
A
Site 45
S307
H
D
S
H
L
M
P
S
P
A
P
V
A
Q
P
Site 46
S324
G
H
V
V
P
C
P
S
P
F
G
R
A
Q
R
Site 47
S334
G
R
A
Q
R
V
P
S
P
G
P
P
T
L
T
Site 48
T341
S
P
G
P
P
T
L
T
S
Y
S
V
L
R
R
Site 49
S342
P
G
P
P
T
L
T
S
Y
S
V
L
R
R
L
Site 50
S344
P
P
T
L
T
S
Y
S
V
L
R
R
L
T
V
Site 51
T350
Y
S
V
L
R
R
L
T
V
Q
P
K
T
R
F
Site 52
T355
R
L
T
V
Q
P
K
T
R
F
T
P
M
P
S
Site 53
T358
V
Q
P
K
T
R
F
T
P
M
P
S
T
P
R
Site 54
S362
T
R
F
T
P
M
P
S
T
P
R
V
Q
Q
A
Site 55
T363
R
F
T
P
M
P
S
T
P
R
V
Q
Q
A
Q
Site 56
S376
A
Q
W
L
R
G
V
S
P
Q
S
C
S
E
D
Site 57
S379
L
R
G
V
S
P
Q
S
C
S
E
D
P
A
L
Site 58
S381
G
V
S
P
Q
S
C
S
E
D
P
A
L
P
W
Site 59
S400
V
R
L
F
D
Q
E
S
C
I
R
S
L
E
G
Site 60
S404
D
Q
E
S
C
I
R
S
L
E
G
S
G
K
P
Site 61
S408
C
I
R
S
L
E
G
S
G
K
P
P
V
A
T
Site 62
T415
S
G
K
P
P
V
A
T
P
S
G
P
H
S
N
Site 63
S417
K
P
P
V
A
T
P
S
G
P
H
S
N
R
T
Site 64
S421
A
T
P
S
G
P
H
S
N
R
T
P
S
L
Q
Site 65
T424
S
G
P
H
S
N
R
T
P
S
L
Q
E
V
K
Site 66
S426
P
H
S
N
R
T
P
S
L
Q
E
V
K
I
Q
Site 67
T478
L
L
T
E
I
S
R
T
L
N
A
T
E
H
N
Site 68
T482
I
S
R
T
L
N
A
T
E
H
N
S
G
T
S
Site 69
S486
L
N
A
T
E
H
N
S
G
T
S
H
L
P
G
Site 70
S529
P
P
E
A
F
C
R
S
E
P
E
I
P
E
P
Site 71
S537
E
P
E
I
P
E
P
S
L
Q
E
Q
L
E
V
Site 72
Y548
Q
L
E
V
P
E
P
Y
P
P
A
E
P
R
P
Site 73
S558
A
E
P
R
P
L
E
S
C
C
R
S
E
P
E
Site 74
S562
P
L
E
S
C
C
R
S
E
P
E
I
P
E
S
Site 75
S569
S
E
P
E
I
P
E
S
S
R
Q
E
Q
L
E
Site 76
Y592
E
P
R
P
L
E
S
Y
C
R
I
E
P
E
I
Site 77
S602
I
E
P
E
I
P
E
S
S
R
Q
E
Q
L
E
Site 78
S625
E
P
G
P
L
Q
P
S
T
Q
G
Q
S
G
P
Site 79
T626
P
G
P
L
Q
P
S
T
Q
G
Q
S
G
P
P
Site 80
S630
Q
P
S
T
Q
G
Q
S
G
P
P
G
P
C
P
Site 81
S644
P
R
V
E
L
G
A
S
E
P
C
T
L
E
H
Site 82
T648
L
G
A
S
E
P
C
T
L
E
H
R
S
L
E
Site 83
S653
P
C
T
L
E
H
R
S
L
E
S
S
L
P
P
Site 84
S657
E
H
R
S
L
E
S
S
L
P
P
C
C
S
Q
Site 85
S663
S
S
L
P
P
C
C
S
Q
W
A
P
A
T
T
Site 86
S671
Q
W
A
P
A
T
T
S
L
I
F
S
S
Q
H
Site 87
S683
S
Q
H
P
L
C
A
S
P
P
I
C
S
L
Q
Site 88
S688
C
A
S
P
P
I
C
S
L
Q
S
L
R
P
P
Site 89
S691
P
P
I
C
S
L
Q
S
L
R
P
P
A
G
Q
Site 90
S702
P
A
G
Q
A
G
L
S
N
L
A
P
R
T
L
Site 91
T708
L
S
N
L
A
P
R
T
L
A
L
R
E
R
L
Site 92
Y737
L
D
D
E
C
A
F
Y
T
S
R
A
P
P
S
Site 93
T738
D
D
E
C
A
F
Y
T
S
R
A
P
P
S
G
Site 94
S744
Y
T
S
R
A
P
P
S
G
P
T
R
V
C
T
Site 95
S777
G
S
A
A
P
Q
G
S
P
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation