PhosphoNET

           
Protein Info 
   
Short Name:  FOXO1A
Full Name:  Forkhead box protein O1
Alias:  FKH1; FKHR; Forkhead box O1; Forkhead box O1A (FKHR); Forkhead box protein O1A; Forkhead in rhabdomyosarcoma; FOXO1
Type:  Transcription factor; Nuclear receptor co-regulator
Mass (Da):  69662
Number AA:  655
UniProt ID:  Q12778
International Prot ID:  IPI00289866
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005654   Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0043565  GO:0016563 PhosphoSite+ KinaseNET
Biological Process:  GO:0006916  GO:0045944  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S22EPLPRPRSCTWPLPR
Site 2T24LPRPRSCTWPLPRPE
Site 3S33PLPRPEFSQSNSATS
Site 4S35PRPEFSQSNSATSSP
Site 5S37PEFSQSNSATSSPAP
Site 6T39FSQSNSATSSPAPSG
Site 7S40SQSNSATSSPAPSGS
Site 8S41QSNSATSSPAPSGSA
Site 9S45ATSSPAPSGSAAANP
Site 10S47SSPAPSGSAAANPDA
Site 11S75ADFMSNLSLLEESED
Site 12S132PPPPGPLSQHPPVPP
Site 13S152LAGQPRKSSSSRRNA
Site 14S153AGQPRKSSSSRRNAW
Site 15S154GQPRKSSSSRRNAWG
Site 16S155QPRKSSSSRRNAWGN
Site 17S164RNAWGNLSYADLITK
Site 18T182SSAEKRLTLSQIYEW
Site 19S184AEKRLTLSQIYEWMV
Site 20Y196WMVKSVPYFKDKGDS
Site 21S203YFKDKGDSNSSAGWK
Site 22S205KDKGDSNSSAGWKNS
Site 23S212SSAGWKNSIRHNLSL
Site 24S218NSIRHNLSLHSKFIR
Site 25S234QNEGTGKSSWWMLNP
Site 26S235NEGTGKSSWWMLNPE
Site 27S246LNPEGGKSGKSPRRR
Site 28S249EGGKSGKSPRRRAAS
Site 29S256SPRRRAASMDNNSKF
Site 30S261AASMDNNSKFAKSRS
Site 31S266NNSKFAKSRSRAAKK
Site 32S268SKFAKSRSRAAKKKA
Site 33S276RAAKKKASLQSGQEG
Site 34S287GQEGAGDSPGSQFSK
Site 35S290GAGDSPGSQFSKWPA
Site 36S293DSPGSQFSKWPASPG
Site 37S298QFSKWPASPGSHSND
Site 38S301KWPASPGSHSNDDFD
Site 39S303PASPGSHSNDDFDNW
Site 40T312DDFDNWSTFRPRTSS
Site 41T317WSTFRPRTSSNASTI
Site 42S318STFRPRTSSNASTIS
Site 43S319TFRPRTSSNASTISG
Site 44S322PRTSSNASTISGRLS
Site 45T323RTSSNASTISGRLSP
Site 46S325SSNASTISGRLSPIM
Site 47S329STISGRLSPIMTEQD
Site 48T333GRLSPIMTEQDDLGE
Site 49S345LGEGDVHSMVYPPSA
Site 50Y348GDVHSMVYPPSAAKM
Site 51S351HSMVYPPSAAKMAST
Site 52S357PSAAKMASTLPSLSE
Site 53S361KMASTLPSLSEISNP
Site 54S363ASTLPSLSEISNPEN
Site 55S383DNLNLLSSPTSLTVS
Site 56S386NLLSSPTSLTVSTQS
Site 57T388LSSPTSLTVSTQSSP
Site 58S390SPTSLTVSTQSSPGT
Site 59T391PTSLTVSTQSSPGTM
Site 60S393SLTVSTQSSPGTMMQ
Site 61S394LTVSTQSSPGTMMQQ
Site 62T397STQSSPGTMMQQTPC
Site 63T402PGTMMQQTPCYSFAP
Site 64S406MQQTPCYSFAPPNTS
Site 65T412YSFAPPNTSLNSPSP
Site 66S413SFAPPNTSLNSPSPN
Site 67S416PPNTSLNSPSPNYQK
Site 68S418NTSLNSPSPNYQKYT
Site 69Y421LNSPSPNYQKYTYGQ
Site 70Y424PSPNYQKYTYGQSSM
Site 71T425SPNYQKYTYGQSSMS
Site 72Y426PNYQKYTYGQSSMSP
Site 73S430KYTYGQSSMSPLPQM
Site 74S432TYGQSSMSPLPQMPI
Site 75S447QTLQDNKSSYGGMSQ
Site 76S448TLQDNKSSYGGMSQY
Site 77Y449LQDNKSSYGGMSQYN
Site 78S453KSSYGGMSQYNCAPG
Site 79Y455SYGGMSQYNCAPGLL
Site 80T467GLLKELLTSDSPPHN
Site 81S468LLKELLTSDSPPHND
Site 82S470KELLTSDSPPHNDIM
Site 83T478PPHNDIMTPVDPGVA
Site 84S489PGVAQPNSRVLGQNV
Site 85S502NVMMGPNSVMSTYGS
Site 86S505MGPNSVMSTYGSQAS
Site 87T506GPNSVMSTYGSQASH
Site 88Y507PNSVMSTYGSQASHN
Site 89S509SVMSTYGSQASHNKM
Site 90S512STYGSQASHNKMMNP
Site 91S532PGHAQQTSAVNGRPL
Site 92T542NGRPLPHTVSTMPHT
Site 93S544RPLPHTVSTMPHTSG
Site 94T556TSGMNRLTQVKTPVQ
Site 95T560NRLTQVKTPVQVPLP
Site 96S573LPHPMQMSALGGYSS
Site 97Y578QMSALGGYSSVSSCN
Site 98S579MSALGGYSSVSSCNG
Site 99S580SALGGYSSVSSCNGY
Site 100S582LGGYSSVSSCNGYGR
Site 101S583GGYSSVSSCNGYGRM
Site 102Y587SVSSCNGYGRMGLLH
Site 103S600LHQEKLPSDLDGMFI
Site 104S640DNVLPNQSFPHSVKT
Site 105S644PNQSFPHSVKTTTHS
Site 106T647SFPHSVKTTTHSWVS
Site 107T648FPHSVKTTTHSWVSG
Site 108S651SVKTTTHSWVSG___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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