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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TEF
Full Name:
Thyrotroph embryonic factor
Alias:
Type:
Mass (Da):
33230
Number AA:
303
UniProt ID:
Q10587
International Prot ID:
IPI00216670
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
A
A
G
E
R
G
L
S
G
S
F
P
L
V
L
Site 2
S34
G
E
R
G
L
S
G
S
F
P
L
V
L
K
K
Site 3
T86
M
P
P
I
W
D
K
T
I
P
Y
D
G
E
S
Site 4
Y89
I
W
D
K
T
I
P
Y
D
G
E
S
F
H
L
Site 5
S113
L
E
N
G
I
P
A
S
P
T
H
L
A
H
N
Site 6
S133
A
E
L
E
G
K
E
S
A
S
S
S
T
A
S
Site 7
S135
L
E
G
K
E
S
A
S
S
S
T
A
S
P
P
Site 8
S136
E
G
K
E
S
A
S
S
S
T
A
S
P
P
S
Site 9
S137
G
K
E
S
A
S
S
S
T
A
S
P
P
S
S
Site 10
T138
K
E
S
A
S
S
S
T
A
S
P
P
S
S
S
Site 11
S140
S
A
S
S
S
T
A
S
P
P
S
S
S
T
A
Site 12
S143
S
S
T
A
S
P
P
S
S
S
T
A
I
F
Q
Site 13
S144
S
T
A
S
P
P
S
S
S
T
A
I
F
Q
P
Site 14
S145
T
A
S
P
P
S
S
S
T
A
I
F
Q
P
S
Site 15
S152
S
T
A
I
F
Q
P
S
E
T
V
S
S
T
E
Site 16
T154
A
I
F
Q
P
S
E
T
V
S
S
T
E
S
S
Site 17
S156
F
Q
P
S
E
T
V
S
S
T
E
S
S
L
E
Site 18
S157
Q
P
S
E
T
V
S
S
T
E
S
S
L
E
K
Site 19
S160
E
T
V
S
S
T
E
S
S
L
E
K
E
R
E
Site 20
S161
T
V
S
S
T
E
S
S
L
E
K
E
R
E
T
Site 21
T168
S
L
E
K
E
R
E
T
P
S
P
I
D
P
N
Site 22
S170
E
K
E
R
E
T
P
S
P
I
D
P
N
C
V
Site 23
Y236
D
E
Q
K
D
E
K
Y
W
T
R
R
K
K
N
Site 24
T238
Q
K
D
E
K
Y
W
T
R
R
K
K
N
N
V
Site 25
T262
R
L
K
E
N
Q
I
T
I
R
A
A
F
L
E
Site 26
T273
A
F
L
E
K
E
N
T
A
L
R
T
E
V
A
Site 27
T291
K
E
V
G
K
C
K
T
I
V
S
K
Y
E
T
Site 28
S294
G
K
C
K
T
I
V
S
K
Y
E
T
K
Y
G
Site 29
Y296
C
K
T
I
V
S
K
Y
E
T
K
Y
G
P
L
Site 30
T298
T
I
V
S
K
Y
E
T
K
Y
G
P
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation