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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
USP17A
Full Name:
Ubiquitin carboxyl-terminal hydrolase 17
Alias:
Deubiquitinating enzyme 17;Ubiquitin thiolesterase 17;Ubiquitin-specific-processing protease 17
Type:
Mass (Da):
59711
Number AA:
530
UniProt ID:
Q0WX57
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
E
D
D
S
L
Y
L
R
G
E
W
Q
F
Site 2
S18
E
W
Q
F
N
H
F
S
K
L
T
S
S
R
P
Site 3
S22
N
H
F
S
K
L
T
S
S
R
P
D
A
A
F
Site 4
S23
H
F
S
K
L
T
S
S
R
P
D
A
A
F
A
Site 5
T35
A
F
A
E
I
Q
R
T
S
L
P
E
K
S
P
Site 6
S36
F
A
E
I
Q
R
T
S
L
P
E
K
S
P
L
Site 7
S41
R
T
S
L
P
E
K
S
P
L
S
C
E
T
R
Site 8
S44
L
P
E
K
S
P
L
S
C
E
T
R
V
D
L
Site 9
S71
P
R
E
K
L
P
L
S
S
R
R
P
A
A
V
Site 10
S72
R
E
K
L
P
L
S
S
R
R
P
A
A
V
G
Site 11
T99
N
A
S
L
Q
C
L
T
Y
T
P
P
L
A
N
Site 12
Y107
Y
T
P
P
L
A
N
Y
M
L
S
R
E
H
S
Site 13
S110
P
L
A
N
Y
M
L
S
R
E
H
S
Q
T
C
Site 14
T116
L
S
R
E
H
S
Q
T
C
H
R
H
K
G
C
Site 15
T191
D
H
H
S
K
D
T
T
L
I
H
Q
I
F
G
Site 16
Y252
E
L
N
G
E
N
A
Y
H
C
G
V
C
L
Q
Site 17
S264
C
L
Q
R
A
P
A
S
K
T
L
T
L
H
T
Site 18
T266
Q
R
A
P
A
S
K
T
L
T
L
H
T
S
A
Site 19
T268
A
P
A
S
K
T
L
T
L
H
T
S
A
K
V
Site 20
T287
L
K
R
F
S
D
V
T
G
N
K
I
A
K
N
Site 21
Y297
K
I
A
K
N
V
Q
Y
P
E
C
L
D
M
Q
Site 22
Y306
E
C
L
D
M
Q
P
Y
M
S
Q
P
N
T
G
Site 23
S308
L
D
M
Q
P
Y
M
S
Q
P
N
T
G
P
L
Site 24
T312
P
Y
M
S
Q
P
N
T
G
P
L
V
Y
V
L
Site 25
S329
V
L
V
H
A
G
W
S
C
H
N
G
H
Y
F
Site 26
Y338
H
N
G
H
Y
F
S
Y
V
K
A
Q
E
G
Q
Site 27
Y347
K
A
Q
E
G
Q
W
Y
K
M
D
D
A
E
V
Site 28
T355
K
M
D
D
A
E
V
T
A
S
S
I
T
S
V
Site 29
Y372
Q
Q
A
Y
V
L
F
Y
I
Q
K
S
E
W
E
Site 30
S382
K
S
E
W
E
R
H
S
E
S
V
S
R
G
R
Site 31
S384
E
W
E
R
H
S
E
S
V
S
R
G
R
E
P
Site 32
S386
E
R
H
S
E
S
V
S
R
G
R
E
P
R
A
Site 33
T399
R
A
L
G
A
E
D
T
D
R
R
A
T
Q
G
Site 34
T404
E
D
T
D
R
R
A
T
Q
G
E
L
K
R
D
Site 35
T429
E
H
L
V
E
R
A
T
Q
E
S
T
L
D
H
Site 36
S432
V
E
R
A
T
Q
E
S
T
L
D
H
W
K
F
Site 37
T446
F
L
Q
E
Q
N
K
T
K
P
E
F
N
V
R
Site 38
Y471
L
V
I
H
Q
S
K
Y
K
C
G
M
K
N
H
Site 39
S485
H
H
P
E
Q
Q
S
S
L
L
N
L
S
S
S
Site 40
S490
Q
S
S
L
L
N
L
S
S
S
T
P
T
H
Q
Site 41
S491
S
S
L
L
N
L
S
S
S
T
P
T
H
Q
E
Site 42
S492
S
L
L
N
L
S
S
S
T
P
T
H
Q
E
S
Site 43
T493
L
L
N
L
S
S
S
T
P
T
H
Q
E
S
M
Site 44
T495
N
L
S
S
S
T
P
T
H
Q
E
S
M
N
T
Site 45
S499
S
T
P
T
H
Q
E
S
M
N
T
G
T
L
A
Site 46
T502
T
H
Q
E
S
M
N
T
G
T
L
A
S
L
R
Site 47
S507
M
N
T
G
T
L
A
S
L
R
G
R
A
R
R
Site 48
S515
L
R
G
R
A
R
R
S
K
G
K
N
K
H
S
Site 49
S522
S
K
G
K
N
K
H
S
K
R
A
L
L
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation