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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C17orf70
Full Name:
Fanconi anemia-associated protein of 100 kDa
Alias:
Chromosome 17 open reading frame 70; FAAP100; FLJ22175; FLJ30151; FP100; Loc80233
Type:
DNA repair
Mass (Da):
93419
Number AA:
881
UniProt ID:
Q0VG06
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y45
S
T
G
S
E
L
V
Y
V
Y
D
Q
E
G
G
Site 2
Y47
G
S
E
L
V
Y
V
Y
D
Q
E
G
G
L
L
Site 3
S89
R
R
G
L
Y
C
L
S
L
D
H
P
G
R
S
Site 4
S96
S
L
D
H
P
G
R
S
R
S
T
S
Q
D
D
Site 5
S98
D
H
P
G
R
S
R
S
T
S
Q
D
D
R
D
Site 6
T99
H
P
G
R
S
R
S
T
S
Q
D
D
R
D
S
Site 7
S100
P
G
R
S
R
S
T
S
Q
D
D
R
D
S
E
Site 8
S106
T
S
Q
D
D
R
D
S
E
D
G
D
Q
P
S
Site 9
S113
S
E
D
G
D
Q
P
S
P
V
I
P
V
D
P
Site 10
S176
Q
I
G
E
V
E
L
S
S
Y
T
P
P
A
G
Site 11
Y178
G
E
V
E
L
S
S
Y
T
P
P
A
G
V
P
Site 12
T179
E
V
E
L
S
S
Y
T
P
P
A
G
V
P
G
Site 13
S203
V
L
C
S
V
S
P
S
G
S
R
V
P
H
D
Site 14
S205
C
S
V
S
P
S
G
S
R
V
P
H
D
L
L
Site 15
S215
P
H
D
L
L
G
G
S
G
G
F
T
L
E
D
Site 16
S263
K
A
L
V
T
S
R
S
A
P
G
D
P
N
A
Site 17
S327
R
M
L
A
I
K
A
S
W
D
E
S
G
K
L
Site 18
S331
I
K
A
S
W
D
E
S
G
K
L
V
P
E
L
Site 19
Y359
C
G
G
G
G
R
V
Y
H
S
T
P
S
D
L
Site 20
S361
G
G
G
R
V
Y
H
S
T
P
S
D
L
C
V
Site 21
T362
G
G
R
V
Y
H
S
T
P
S
D
L
C
V
V
Site 22
S375
V
V
D
L
S
R
G
S
T
P
L
G
P
E
Q
Site 23
T376
V
D
L
S
R
G
S
T
P
L
G
P
E
Q
P
Site 24
S410
S
V
V
S
L
S
A
S
P
R
T
H
E
G
G
Site 25
T413
S
L
S
A
S
P
R
T
H
E
G
G
T
K
L
Site 26
T431
S
A
K
G
R
L
M
T
C
S
L
D
L
D
S
Site 27
S433
K
G
R
L
M
T
C
S
L
D
L
D
S
E
M
Site 28
S438
T
C
S
L
D
L
D
S
E
M
P
G
P
A
R
Site 29
T447
M
P
G
P
A
R
M
T
T
E
S
A
G
Q
K
Site 30
T448
P
G
P
A
R
M
T
T
E
S
A
G
Q
K
I
Site 31
S450
P
A
R
M
T
T
E
S
A
G
Q
K
I
K
E
Site 32
S460
Q
K
I
K
E
L
L
S
G
I
G
N
I
S
E
Site 33
S470
G
N
I
S
E
R
V
S
F
L
K
K
A
V
D
Site 34
T484
D
Q
R
N
K
A
L
T
S
L
N
E
A
M
N
Site 35
S498
N
V
S
C
A
L
L
S
S
G
T
G
P
R
P
Site 36
S507
G
T
G
P
R
P
I
S
C
T
T
S
T
T
W
Site 37
T509
G
P
R
P
I
S
C
T
T
S
T
T
W
S
R
Site 38
S511
R
P
I
S
C
T
T
S
T
T
W
S
R
L
Q
Site 39
T513
I
S
C
T
T
S
T
T
W
S
R
L
Q
T
Q
Site 40
S515
C
T
T
S
T
T
W
S
R
L
Q
T
Q
D
V
Site 41
T519
T
T
W
S
R
L
Q
T
Q
D
V
L
M
A
T
Site 42
S532
A
T
C
V
L
E
N
S
S
S
F
S
L
D
Q
Site 43
S534
C
V
L
E
N
S
S
S
F
S
L
D
Q
G
W
Site 44
S536
L
E
N
S
S
S
F
S
L
D
Q
G
W
T
L
Site 45
T581
P
G
A
R
R
E
V
T
L
P
L
G
P
G
E
Site 46
S617
V
G
G
A
L
A
P
S
D
S
E
D
P
F
L
Site 47
S619
G
A
L
A
P
S
D
S
E
D
P
F
L
D
E
Site 48
S629
P
F
L
D
E
C
P
S
D
V
L
P
E
Q
E
Site 49
T663
P
G
L
A
L
P
H
T
R
A
P
S
P
L
G
Site 50
S667
L
P
H
T
R
A
P
S
P
L
G
P
T
R
D
Site 51
T672
A
P
S
P
L
G
P
T
R
D
P
V
A
T
F
Site 52
T678
P
T
R
D
P
V
A
T
F
L
E
T
C
R
E
Site 53
S688
E
T
C
R
E
P
G
S
Q
P
A
G
P
A
S
Site 54
S695
S
Q
P
A
G
P
A
S
L
R
A
E
Y
L
P
Site 55
Y700
P
A
S
L
R
A
E
Y
L
P
P
S
V
A
S
Site 56
S704
R
A
E
Y
L
P
P
S
V
A
S
I
K
V
S
Site 57
S793
E
I
Q
V
E
S
S
S
L
A
D
I
C
R
A
Site 58
Y829
A
P
D
L
R
V
Q
Y
L
R
Q
I
H
A
N
Site 59
T846
T
L
L
R
E
V
Q
T
L
R
D
R
L
C
T
Site 60
T853
T
L
R
D
R
L
C
T
E
D
E
A
S
S
C
Site 61
S858
L
C
T
E
D
E
A
S
S
C
A
T
A
Q
R
Site 62
T862
D
E
A
S
S
C
A
T
A
Q
R
L
L
Q
V
Site 63
Y870
A
Q
R
L
L
Q
V
Y
R
Q
L
R
H
P
S
Site 64
S877
Y
R
Q
L
R
H
P
S
L
I
L
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation