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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CGNL1
Full Name:
Cingulin-like protein 1
Alias:
Cingulin-like 1; FLJ14957; JACOP; Junction-associated coiled-coil; KIAA1749; Paracingulin
Type:
Adhesion
Mass (Da):
149045
Number AA:
1302
UniProt ID:
Q0VF96
International Prot ID:
IPI00307829
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016459
GO:0005923
Uniprot
OncoNet
Molecular Function:
GO:0003774
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
E
L
Y
F
G
E
Y
Q
H
V
Q
Q
E
Y
Site 2
S23
G
V
H
L
R
L
A
S
D
D
T
Q
K
S
R
Site 3
T26
L
R
L
A
S
D
D
T
Q
K
S
R
S
S
Q
Site 4
S29
A
S
D
D
T
Q
K
S
R
S
S
Q
N
S
K
Site 5
S31
D
D
T
Q
K
S
R
S
S
Q
N
S
K
A
G
Site 6
S32
D
T
Q
K
S
R
S
S
Q
N
S
K
A
G
S
Site 7
S35
K
S
R
S
S
Q
N
S
K
A
G
S
Y
G
V
Site 8
S39
S
Q
N
S
K
A
G
S
Y
G
V
S
I
R
V
Site 9
Y40
Q
N
S
K
A
G
S
Y
G
V
S
I
R
V
Q
Site 10
S43
K
A
G
S
Y
G
V
S
I
R
V
Q
G
I
D
Site 11
Y54
Q
G
I
D
G
H
P
Y
I
V
L
N
N
T
E
Site 12
T67
T
E
R
C
L
A
G
T
S
F
S
E
N
G
P
Site 13
S68
E
R
C
L
A
G
T
S
F
S
E
N
G
P
P
Site 14
S88
I
N
N
L
P
L
H
S
S
N
G
S
V
P
K
Site 15
S89
N
N
L
P
L
H
S
S
N
G
S
V
P
K
E
Site 16
S92
P
L
H
S
S
N
G
S
V
P
K
E
N
S
E
Site 17
Y108
L
Q
L
P
E
N
P
Y
A
Q
P
S
P
I
R
Site 18
S112
E
N
P
Y
A
Q
P
S
P
I
R
N
L
K
Q
Site 19
S136
V
L
D
R
K
D
G
S
V
K
P
S
H
L
L
Site 20
S140
K
D
G
S
V
K
P
S
H
L
L
N
F
Q
R
Site 21
T177
S
E
S
N
W
L
K
T
L
T
E
E
G
I
N
Site 22
T179
S
N
W
L
K
T
L
T
E
E
G
I
N
N
K
Site 23
T190
I
N
N
K
K
P
W
T
C
F
P
K
P
S
N
Site 24
S196
W
T
C
F
P
K
P
S
N
S
Q
P
T
S
P
Site 25
S198
C
F
P
K
P
S
N
S
Q
P
T
S
P
S
L
Site 26
T201
K
P
S
N
S
Q
P
T
S
P
S
L
E
D
P
Site 27
S202
P
S
N
S
Q
P
T
S
P
S
L
E
D
P
A
Site 28
S204
N
S
Q
P
T
S
P
S
L
E
D
P
A
K
S
Site 29
T231
I
E
D
P
K
K
Q
T
S
V
C
V
N
V
Q
Site 30
S232
E
D
P
K
K
Q
T
S
V
C
V
N
V
Q
S
Site 31
S239
S
V
C
V
N
V
Q
S
C
T
K
E
R
V
G
Site 32
T241
C
V
N
V
Q
S
C
T
K
E
R
V
G
E
E
Site 33
S253
G
E
E
A
L
F
T
S
G
R
P
L
T
A
H
Site 34
T258
F
T
S
G
R
P
L
T
A
H
S
P
H
A
H
Site 35
S261
G
R
P
L
T
A
H
S
P
H
A
H
P
E
T
Site 36
T268
S
P
H
A
H
P
E
T
K
K
T
R
P
D
V
Site 37
T271
A
H
P
E
T
K
K
T
R
P
D
V
L
P
F
Site 38
S283
L
P
F
R
R
Q
D
S
A
G
P
V
L
D
G
Site 39
S293
P
V
L
D
G
A
R
S
R
R
S
S
S
S
S
Site 40
S296
D
G
A
R
S
R
R
S
S
S
S
S
T
T
P
Site 41
S297
G
A
R
S
R
R
S
S
S
S
S
T
T
P
T
Site 42
S298
A
R
S
R
R
S
S
S
S
S
T
T
P
T
S
Site 43
S299
R
S
R
R
S
S
S
S
S
T
T
P
T
S
A
Site 44
S300
S
R
R
S
S
S
S
S
T
T
P
T
S
A
N
Site 45
T301
R
R
S
S
S
S
S
T
T
P
T
S
A
N
S
Site 46
T302
R
S
S
S
S
S
T
T
P
T
S
A
N
S
L
Site 47
T304
S
S
S
S
T
T
P
T
S
A
N
S
L
Y
R
Site 48
S305
S
S
S
T
T
P
T
S
A
N
S
L
Y
R
F
Site 49
S308
T
T
P
T
S
A
N
S
L
Y
R
F
L
L
D
Site 50
Y310
P
T
S
A
N
S
L
Y
R
F
L
L
D
D
Q
Site 51
Y334
N
R
H
E
N
R
R
Y
I
P
F
L
P
G
T
Site 52
T341
Y
I
P
F
L
P
G
T
G
R
D
I
D
T
G
Site 53
T347
G
T
G
R
D
I
D
T
G
S
I
P
G
V
D
Site 54
S349
G
R
D
I
D
T
G
S
I
P
G
V
D
Q
L
Site 55
S372
G
L
Q
R
R
G
R
S
G
K
R
N
R
I
N
Site 56
S386
N
P
D
D
R
K
R
S
R
S
V
D
S
A
F
Site 57
S388
D
D
R
K
R
S
R
S
V
D
S
A
F
P
F
Site 58
S391
K
R
S
R
S
V
D
S
A
F
P
F
G
L
Q
Site 59
S401
P
F
G
L
Q
G
N
S
E
Y
L
I
E
F
S
Site 60
Y403
G
L
Q
G
N
S
E
Y
L
I
E
F
S
R
N
Site 61
S414
F
S
R
N
L
G
K
S
S
E
H
L
L
R
P
Site 62
S422
S
E
H
L
L
R
P
S
Q
V
C
P
Q
R
P
Site 63
S431
V
C
P
Q
R
P
L
S
Q
E
R
R
G
K
Q
Site 64
S439
Q
E
R
R
G
K
Q
S
V
G
R
T
F
A
K
Site 65
T443
G
K
Q
S
V
G
R
T
F
A
K
L
Q
G
A
Site 66
S455
Q
G
A
A
H
G
A
S
C
A
H
S
R
P
P
Site 67
S459
H
G
A
S
C
A
H
S
R
P
P
Q
P
N
I
Site 68
S476
K
V
L
E
T
E
G
S
Q
E
S
T
V
I
R
Site 69
T480
T
E
G
S
Q
E
S
T
V
I
R
A
P
S
L
Site 70
S486
S
T
V
I
R
A
P
S
L
G
A
Q
S
K
K
Site 71
T499
K
K
E
E
E
V
K
T
A
T
A
T
L
M
L
Site 72
S514
Q
N
R
A
A
A
T
S
P
D
S
G
A
K
K
Site 73
S517
A
A
A
T
S
P
D
S
G
A
K
K
I
S
V
Site 74
S523
D
S
G
A
K
K
I
S
V
K
T
F
P
S
A
Site 75
T526
A
K
K
I
S
V
K
T
F
P
S
A
S
N
T
Site 76
S531
V
K
T
F
P
S
A
S
N
T
Q
A
T
P
D
Site 77
T533
T
F
P
S
A
S
N
T
Q
A
T
P
D
L
L
Site 78
T536
S
A
S
N
T
Q
A
T
P
D
L
L
K
G
Q
Site 79
Y560
E
T
A
K
Q
I
L
Y
N
Y
L
K
E
G
S
Site 80
Y562
A
K
Q
I
L
Y
N
Y
L
K
E
G
S
T
D
Site 81
S567
Y
N
Y
L
K
E
G
S
T
D
N
D
D
A
T
Site 82
T568
N
Y
L
K
E
G
S
T
D
N
D
D
A
T
K
Site 83
T574
S
T
D
N
D
D
A
T
K
R
K
V
N
L
V
Site 84
S590
E
K
I
Q
T
L
K
S
R
A
A
G
S
A
Q
Site 85
S607
N
Q
A
C
N
S
T
S
E
V
K
D
L
L
E
Site 86
S617
K
D
L
L
E
Q
K
S
K
L
T
I
E
V
A
Site 87
S656
A
N
L
E
E
L
R
S
Q
H
N
E
K
V
E
Site 88
T667
E
K
V
E
E
N
S
T
L
Q
Q
R
L
E
E
Site 89
T698
M
E
R
E
Q
H
Q
T
E
I
R
D
L
Q
D
Site 90
S708
R
D
L
Q
D
Q
L
S
E
M
H
D
E
L
D
Site 91
S716
E
M
H
D
E
L
D
S
A
K
R
S
E
D
R
Site 92
S720
E
L
D
S
A
K
R
S
E
D
R
E
K
G
A
Site 93
T761
R
K
R
E
R
E
L
T
A
L
K
G
A
L
K
Site 94
S772
G
A
L
K
E
E
V
S
S
H
D
Q
E
M
D
Site 95
S773
A
L
K
E
E
V
S
S
H
D
Q
E
M
D
K
Site 96
S795
E
L
Q
A
L
R
E
S
V
E
E
A
T
K
N
Site 97
S808
K
N
V
E
V
L
A
S
R
S
N
T
S
E
Q
Site 98
T812
V
L
A
S
R
S
N
T
S
E
Q
D
Q
A
G
Site 99
Y869
A
K
E
T
L
K
K
Y
E
G
E
I
R
Q
L
Site 100
S892
K
E
E
K
E
A
V
S
A
R
R
A
L
E
N
Site 101
S909
E
A
A
Q
G
N
L
S
Q
T
T
Q
E
Q
K
Site 102
S919
T
Q
E
Q
K
Q
L
S
E
K
L
K
E
E
S
Site 103
S926
S
E
K
L
K
E
E
S
E
Q
K
E
Q
L
R
Site 104
T966
D
I
V
E
A
S
R
T
S
T
L
E
L
Q
N
Site 105
S967
I
V
E
A
S
R
T
S
T
L
E
L
Q
N
Q
Site 106
T968
V
E
A
S
R
T
S
T
L
E
L
Q
N
Q
L
Site 107
Y978
L
Q
N
Q
L
D
E
Y
K
E
K
N
R
R
E
Site 108
T997
Q
R
Q
L
K
E
K
T
L
E
A
E
K
S
R
Site 109
S1003
K
T
L
E
A
E
K
S
R
L
T
A
M
K
M
Site 110
T1006
E
A
E
K
S
R
L
T
A
M
K
M
Q
D
E
Site 111
Y1024
M
E
E
E
L
R
D
Y
Q
R
A
Q
D
E
A
Site 112
Y1047
Q
T
L
K
D
L
E
Y
E
L
E
A
K
S
H
Site 113
S1060
S
H
L
K
D
D
R
S
R
L
V
K
Q
M
E
Site 114
S1071
K
Q
M
E
D
K
V
S
Q
L
E
M
E
L
E
Site 115
S1084
L
E
E
E
R
N
N
S
D
L
L
S
E
R
I
Site 116
S1088
R
N
N
S
D
L
L
S
E
R
I
S
R
S
R
Site 117
S1092
D
L
L
S
E
R
I
S
R
S
R
E
Q
M
E
Site 118
S1121
D
L
E
C
D
K
I
S
L
E
R
Q
N
K
D
Site 119
S1131
R
Q
N
K
D
L
K
S
R
I
I
H
L
E
G
Site 120
S1139
R
I
I
H
L
E
G
S
Y
R
S
S
K
E
G
Site 121
S1143
L
E
G
S
Y
R
S
S
K
E
G
L
V
V
Q
Site 122
S1164
E
L
E
D
R
L
E
S
E
E
R
D
R
A
N
Site 123
S1175
D
R
A
N
L
Q
L
S
N
R
R
L
E
R
K
Site 124
S1196
Q
V
D
D
E
H
L
S
L
T
D
Q
K
D
Q
Site 125
S1205
T
D
Q
K
D
Q
L
S
L
R
L
K
A
M
K
Site 126
S1227
E
E
I
D
R
L
E
S
S
K
K
K
L
Q
R
Site 127
S1252
H
L
Q
G
Q
L
N
S
M
K
K
D
L
R
L
Site 128
S1264
L
R
L
K
K
L
P
S
K
V
L
D
D
M
D
Site 129
S1277
M
D
D
D
D
D
L
S
T
D
G
G
S
L
Y
Site 130
T1278
D
D
D
D
D
L
S
T
D
G
G
S
L
Y
E
Site 131
S1282
D
L
S
T
D
G
G
S
L
Y
E
A
P
V
S
Site 132
Y1284
S
T
D
G
G
S
L
Y
E
A
P
V
S
Y
T
Site 133
S1289
S
L
Y
E
A
P
V
S
Y
T
F
S
K
D
S
Site 134
T1291
Y
E
A
P
V
S
Y
T
F
S
K
D
S
T
V
Site 135
S1293
A
P
V
S
Y
T
F
S
K
D
S
T
V
A
S
Site 136
S1296
S
Y
T
F
S
K
D
S
T
V
A
S
Q
I
_
Site 137
T1297
Y
T
F
S
K
D
S
T
V
A
S
Q
I
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation