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Updated November 2019
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Protein Info
Short Name:
DNAH14
Full Name:
Dynein heavy chain 14, axonemal
Alias:
Axonemal beta dynein heavy chain 14;Ciliary dynein heavy chain 14
Type:
Mass (Da):
399895
Number AA:
3507
UniProt ID:
Q0VDD8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y79
V
T
S
G
A
A
A
Y
P
R
W
N
L
A
R
Site 2
T96
A
P
P
H
L
P
G
T
Q
D
P
L
R
R
V
Site 3
T107
L
R
R
V
R
D
P
T
P
I
V
A
S
S
P
Site 4
S113
P
T
P
I
V
A
S
S
P
G
R
R
R
G
S
Site 5
S120
S
P
G
R
R
R
G
S
W
S
G
G
Y
G
Q
Site 6
S122
G
R
R
R
G
S
W
S
G
G
Y
G
Q
E
A
Site 7
S130
G
G
Y
G
Q
E
A
S
E
P
G
V
V
G
L
Site 8
S169
Q
E
G
P
Q
R
P
S
D
H
G
A
A
E
K
Site 9
T180
A
A
E
K
H
M
E
T
F
I
P
I
D
L
T
Site 10
T187
T
F
I
P
I
D
L
T
T
E
N
Q
E
M
D
Site 11
T188
F
I
P
I
D
L
T
T
E
N
Q
E
M
D
K
Site 12
T200
M
D
K
E
E
T
K
T
K
P
R
L
L
R
Y
Site 13
Y207
T
K
P
R
L
L
R
Y
E
E
K
K
Y
E
D
Site 14
Y212
L
R
Y
E
E
K
K
Y
E
D
V
K
P
L
E
Site 15
Y233
A
E
K
E
T
L
E
Y
K
T
V
R
T
F
S
Site 16
T235
K
E
T
L
E
Y
K
T
V
R
T
F
S
E
S
Site 17
T238
L
E
Y
K
T
V
R
T
F
S
E
S
L
K
S
Site 18
S240
Y
K
T
V
R
T
F
S
E
S
L
K
S
E
K
Site 19
S242
T
V
R
T
F
S
E
S
L
K
S
E
K
T
E
Site 20
S245
T
F
S
E
S
L
K
S
E
K
T
E
E
P
K
Site 21
T248
E
S
L
K
S
E
K
T
E
E
P
K
D
D
D
Site 22
T271
R
E
K
L
G
W
Q
T
I
L
P
Q
H
S
L
Site 23
S277
Q
T
I
L
P
Q
H
S
L
K
Y
G
S
S
K
Site 24
Y280
L
P
Q
H
S
L
K
Y
G
S
S
K
I
A
I
Site 25
Y304
E
D
D
G
E
F
V
Y
C
L
P
R
K
S
P
Site 26
S310
V
Y
C
L
P
R
K
S
P
K
S
L
Y
N
P
Site 27
S313
L
P
R
K
S
P
K
S
L
Y
N
P
Y
D
L
Site 28
Y315
R
K
S
P
K
S
L
Y
N
P
Y
D
L
Q
V
Site 29
S347
S
F
I
S
K
L
D
S
S
R
T
Y
S
L
D
Site 30
S348
F
I
S
K
L
D
S
S
R
T
Y
S
L
D
E
Site 31
T350
S
K
L
D
S
S
R
T
Y
S
L
D
E
F
C
Site 32
Y351
K
L
D
S
S
R
T
Y
S
L
D
E
F
C
E
Site 33
S352
L
D
S
S
R
T
Y
S
L
D
E
F
C
E
E
Site 34
S380
D
I
R
N
K
A
I
S
E
M
K
S
T
F
L
Site 35
S384
K
A
I
S
E
M
K
S
T
F
L
K
V
A
E
Site 36
T385
A
I
S
E
M
K
S
T
F
L
K
V
A
E
K
Site 37
Y398
E
K
N
E
I
K
E
Y
F
E
S
K
L
S
E
Site 38
S401
E
I
K
E
Y
F
E
S
K
L
S
E
D
D
T
Site 39
S404
E
Y
F
E
S
K
L
S
E
D
D
T
T
H
F
Site 40
T408
S
K
L
S
E
D
D
T
T
H
F
K
L
P
K
Site 41
T409
K
L
S
E
D
D
T
T
H
F
K
L
P
K
Y
Site 42
Y416
T
H
F
K
L
P
K
Y
R
R
L
L
E
T
F
Site 43
S462
G
S
A
G
M
P
F
S
V
E
K
K
N
E
N
Site 44
T473
K
N
E
N
L
I
R
T
F
K
D
N
S
F
P
Site 45
S478
I
R
T
F
K
D
N
S
F
P
T
G
K
T
T
Site 46
S495
C
E
E
L
V
D
N
S
K
L
H
A
I
S
V
Site 47
S501
N
S
K
L
H
A
I
S
V
Q
K
S
E
V
K
Site 48
S505
H
A
I
S
V
Q
K
S
E
V
K
T
D
T
D
Site 49
T509
V
Q
K
S
E
V
K
T
D
T
D
I
N
E
I
Site 50
T511
K
S
E
V
K
T
D
T
D
I
N
E
I
L
N
Site 51
S519
D
I
N
E
I
L
N
S
V
E
V
G
K
D
L
Site 52
T529
V
G
K
D
L
R
K
T
Y
A
P
I
F
E
V
Site 53
Y530
G
K
D
L
R
K
T
Y
A
P
I
F
E
V
N
Site 54
S546
C
L
R
I
P
A
E
S
D
S
S
E
N
S
K
Site 55
S548
R
I
P
A
E
S
D
S
S
E
N
S
K
E
N
Site 56
S549
I
P
A
E
S
D
S
S
E
N
S
K
E
N
F
Site 57
S552
E
S
D
S
S
E
N
S
K
E
N
F
H
E
S
Site 58
S559
S
K
E
N
F
H
E
S
D
Q
C
P
E
E
C
Site 59
S585
D
N
C
V
K
K
H
S
S
E
E
L
L
P
K
Site 60
S596
L
L
P
K
A
K
K
S
K
E
I
S
Y
N
L
Site 61
S600
A
K
K
S
K
E
I
S
Y
N
L
E
D
I
I
Site 62
Y642
K
T
G
S
I
I
H
Y
K
E
Q
T
R
W
P
Site 63
Y682
S
M
G
L
V
N
A
Y
S
H
K
F
I
K
Y
Site 64
Y689
Y
S
H
K
F
I
K
Y
C
T
M
T
E
K
A
Site 65
S700
T
E
K
A
K
I
M
S
M
K
I
S
S
M
G
Site 66
S704
K
I
M
S
M
K
I
S
S
M
G
E
L
T
S
Site 67
S711
S
S
M
G
E
L
T
S
K
E
F
E
A
I
L
Site 68
Y724
I
L
N
R
F
R
N
Y
F
R
H
I
V
N
M
Site 69
T756
Q
Q
L
E
C
D
P
T
E
I
E
E
F
L
E
Site 70
S776
N
A
I
S
S
K
I
S
K
L
E
K
E
F
L
Site 71
T784
K
L
E
K
E
F
L
T
M
S
Q
L
Y
S
V
Site 72
S786
E
K
E
F
L
T
M
S
Q
L
Y
S
V
A
K
Site 73
S790
L
T
M
S
Q
L
Y
S
V
A
K
H
H
Q
I
Site 74
S819
L
K
F
S
Q
L
K
S
S
M
K
L
S
K
I
Site 75
S820
K
F
S
Q
L
K
S
S
M
K
L
S
K
I
N
Site 76
S824
L
K
S
S
M
K
L
S
K
I
N
K
D
T
A
Site 77
T887
S
G
E
A
A
S
L
T
N
K
A
K
A
Y
S
Site 78
Y896
K
A
K
A
Y
S
H
Y
Q
D
C
F
S
D
S
Site 79
S909
D
S
Q
S
H
M
H
S
V
N
V
E
E
I
T
Site 80
T931
S
D
I
E
G
D
L
T
L
R
K
K
L
W
E
Site 81
S953
A
S
W
E
W
R
N
S
S
L
Q
S
I
D
V
Site 82
S954
S
W
E
W
R
N
S
S
L
Q
S
I
D
V
E
Site 83
S957
W
R
N
S
S
L
Q
S
I
D
V
E
S
V
Q
Site 84
S962
L
Q
S
I
D
V
E
S
V
Q
R
N
V
S
K
Site 85
S968
E
S
V
Q
R
N
V
S
K
L
M
H
I
I
S
Site 86
S994
I
P
S
I
D
D
I
S
A
Q
L
E
E
S
Q
Site 87
Y1023
I
K
S
Q
I
M
F
Y
N
D
C
V
K
S
F
Site 88
S1029
F
Y
N
D
C
V
K
S
F
V
S
S
Y
S
R
Site 89
S1033
C
V
K
S
F
V
S
S
Y
S
R
E
K
L
E
Site 90
Y1034
V
K
S
F
V
S
S
Y
S
R
E
K
L
E
K
Site 91
S1035
K
S
F
V
S
S
Y
S
R
E
K
L
E
K
V
Site 92
T1061
A
D
L
V
V
L
D
T
S
N
S
R
T
K
A
Site 93
T1066
L
D
T
S
N
S
R
T
K
A
I
L
G
A
L
Site 94
Y1116
N
E
K
Q
K
L
C
Y
V
S
Q
G
N
A
S
Site 95
S1118
K
Q
K
L
C
Y
V
S
Q
G
N
A
S
F
T
Site 96
Y1126
Q
G
N
A
S
F
T
Y
G
Y
E
Y
L
G
C
Site 97
Y1130
S
F
T
Y
G
Y
E
Y
L
G
C
T
S
R
L
Site 98
T1173
A
G
T
G
K
T
E
T
V
K
D
L
A
K
C
Site 99
Y1244
F
I
T
M
N
P
R
Y
G
G
G
V
E
L
P
Site 100
S1256
E
L
P
D
N
L
K
S
L
F
R
P
V
A
M
Site 101
S1283
L
F
S
F
G
F
K
S
A
N
S
L
S
G
K
Site 102
S1286
F
G
F
K
S
A
N
S
L
S
G
K
L
T
N
Site 103
T1292
N
S
L
S
G
K
L
T
N
L
Y
E
L
A
R
Site 104
Y1295
S
G
K
L
T
N
L
Y
E
L
A
R
K
Q
L
Site 105
S1303
E
L
A
R
K
Q
L
S
Q
Q
D
H
Y
N
F
Site 106
Y1308
Q
L
S
Q
Q
D
H
Y
N
F
G
L
R
S
L
Site 107
T1333
K
R
E
F
K
C
D
T
S
D
S
L
S
E
A
Site 108
S1334
R
E
F
K
C
D
T
S
D
S
L
S
E
A
D
Site 109
S1336
F
K
C
D
T
S
D
S
L
S
E
A
D
E
T
Site 110
S1338
C
D
T
S
D
S
L
S
E
A
D
E
T
L
I
Site 111
S1354
I
E
A
I
R
E
A
S
L
P
K
C
P
P
E
Site 112
S1405
L
G
L
Q
N
W
S
S
Q
K
E
K
I
I
Q
Site 113
T1434
G
P
T
G
G
G
K
T
T
V
R
R
I
L
E
Site 114
T1435
P
T
G
G
G
K
T
T
V
R
R
I
L
E
K
Site 115
S1460
L
S
V
A
E
R
K
S
A
S
K
I
S
E
R
Site 116
S1465
R
K
S
A
S
K
I
S
E
R
K
G
K
V
D
Site 117
T1494
Y
G
Q
L
D
P
N
T
M
E
W
T
D
G
L
Site 118
S1503
E
W
T
D
G
L
L
S
A
T
I
R
S
Y
V
Site 119
Y1509
L
S
A
T
I
R
S
Y
V
Y
F
N
T
P
K
Site 120
Y1511
A
T
I
R
S
Y
V
Y
F
N
T
P
K
N
T
Site 121
T1514
R
S
Y
V
Y
F
N
T
P
K
N
T
K
K
D
Site 122
S1528
D
I
D
L
R
L
K
S
R
I
S
D
L
S
N
Site 123
S1531
L
R
L
K
S
R
I
S
D
L
S
N
V
F
K
Site 124
S1534
K
S
R
I
S
D
L
S
N
V
F
K
L
D
S
Site 125
S1541
S
N
V
F
K
L
D
S
S
D
T
T
E
T
D
Site 126
S1542
N
V
F
K
L
D
S
S
D
T
T
E
T
D
D
Site 127
T1545
K
L
D
S
S
D
T
T
E
T
D
D
N
I
F
Site 128
S1588
F
W
V
E
N
L
N
S
V
L
D
D
T
R
T
Site 129
T1595
S
V
L
D
D
T
R
T
L
C
L
A
N
S
E
Site 130
S1601
R
T
L
C
L
A
N
S
E
R
I
A
L
T
N
Site 131
S1623
V
D
N
L
S
Q
A
S
P
A
T
V
S
R
C
Site 132
Y1645
V
D
L
G
W
E
P
Y
V
K
S
W
L
L
K
Site 133
S1648
G
W
E
P
Y
V
K
S
W
L
L
K
T
S
K
Site 134
T1653
V
K
S
W
L
L
K
T
S
K
I
I
S
Q
S
Site 135
S1654
K
S
W
L
L
K
T
S
K
I
I
S
Q
S
G
Site 136
Y1689
N
R
Q
K
F
Q
P
Y
P
M
E
D
I
T
V
Site 137
S1720
K
N
G
G
F
E
Q
S
D
D
L
N
D
T
S
Site 138
T1726
Q
S
D
D
L
N
D
T
S
S
K
E
A
N
S
Site 139
S1728
D
D
L
N
D
T
S
S
K
E
A
N
S
Q
R
Site 140
S1733
T
S
S
K
E
A
N
S
Q
R
E
S
V
T
F
Site 141
S1737
E
A
N
S
Q
R
E
S
V
T
F
K
D
I
E
Site 142
T1739
N
S
Q
R
E
S
V
T
F
K
D
I
E
K
R
Site 143
T1750
I
E
K
R
D
E
N
T
W
Y
P
E
K
N
P
Site 144
Y1752
K
R
D
E
N
T
W
Y
P
E
K
N
P
D
K
Site 145
T1761
E
K
N
P
D
K
L
T
K
I
I
Q
K
L
F
Site 146
S1795
E
N
I
P
F
C
P
S
L
E
P
D
S
L
A
Site 147
S1800
C
P
S
L
E
P
D
S
L
A
K
V
T
Y
D
Site 148
Y1806
D
S
L
A
K
V
T
Y
D
F
D
K
L
V
H
Site 149
S1820
H
E
L
F
G
N
S
S
Q
V
G
I
N
L
P
Site 150
T1857
D
L
V
P
N
D
Q
T
L
I
Q
R
D
N
P
Site 151
T1865
L
I
Q
R
D
N
P
T
K
K
P
E
V
R
T
Site 152
S1888
D
H
K
G
V
V
V
S
T
I
N
F
S
T
N
Site 153
T1913
L
K
K
L
I
R
R
T
K
D
T
L
G
A
P
Site 154
T1916
L
I
R
R
T
K
D
T
L
G
A
P
K
N
N
Site 155
Y1940
N
M
P
V
S
D
M
Y
G
A
Q
P
P
L
E
Site 156
T1961
D
L
G
G
V
Y
D
T
E
K
N
T
W
K
N
Site 157
Y2035
Y
L
T
D
N
K
L
Y
R
V
P
I
S
H
K
Site 158
S2079
N
L
N
I
E
Q
D
S
F
L
E
D
L
N
Y
Site 159
S2089
E
D
L
N
Y
I
I
S
S
G
R
I
P
D
L
Site 160
Y2111
S
I
A
M
K
I
R
Y
L
T
E
Q
S
G
H
Site 161
T2113
A
M
K
I
R
Y
L
T
E
Q
S
G
H
M
D
Site 162
S2124
G
H
M
D
N
R
Q
S
L
L
S
F
F
Q
K
Site 163
S2127
D
N
R
Q
S
L
L
S
F
F
Q
K
R
I
Y
Site 164
Y2134
S
F
F
Q
K
R
I
Y
K
N
L
H
I
F
V
Site 165
S2149
I
M
S
P
E
G
P
S
F
R
Q
N
C
R
V
Site 166
Y2157
F
R
Q
N
C
R
V
Y
P
S
M
I
S
S
C
Site 167
Y2169
S
S
C
T
I
D
W
Y
E
R
W
P
E
E
A
Site 168
Y2219
M
K
D
L
N
R
K
Y
F
E
E
T
G
R
F
Site 169
Y2227
F
E
E
T
G
R
F
Y
Y
T
T
P
N
S
Y
Site 170
Y2228
E
E
T
G
R
F
Y
Y
T
T
P
N
S
Y
L
Site 171
T2229
E
T
G
R
F
Y
Y
T
T
P
N
S
Y
L
Q
Site 172
T2230
T
G
R
F
Y
Y
T
T
P
N
S
Y
L
Q
F
Site 173
T2254
A
R
E
E
E
M
Q
T
K
R
D
R
F
H
M
Site 174
S2305
M
E
K
L
R
K
D
S
Q
V
V
E
K
V
Q
Site 175
Y2332
E
V
R
I
V
E
D
Y
A
Q
K
T
A
N
E
Site 176
S2342
K
T
A
N
E
L
K
S
V
L
P
A
F
D
K
Site 177
T2429
V
K
L
K
K
I
V
T
L
P
D
F
N
P
H
Site 178
Y2509
Q
G
L
P
H
G
Q
Y
S
V
E
N
A
I
L
Site 179
S2543
W
I
R
Q
M
E
G
S
R
L
Q
K
L
S
I
Site 180
S2549
G
S
R
L
Q
K
L
S
I
E
D
S
N
Y
T
Site 181
S2553
Q
K
L
S
I
E
D
S
N
Y
T
K
K
I
E
Site 182
Y2555
L
S
I
E
D
S
N
Y
T
K
K
I
E
N
A
Site 183
T2565
K
I
E
N
A
M
K
T
G
G
S
V
L
L
Q
Site 184
S2568
N
A
M
K
T
G
G
S
V
L
L
Q
S
C
Q
Site 185
S2573
G
G
S
V
L
L
Q
S
C
Q
A
S
T
W
R
Site 186
S2577
L
L
Q
S
C
Q
A
S
T
W
R
K
K
L
Y
Site 187
T2578
L
Q
S
C
Q
A
S
T
W
R
K
K
L
Y
L
Site 188
Y2584
S
T
W
R
K
K
L
Y
L
S
T
E
I
D
N
Site 189
S2586
W
R
K
K
L
Y
L
S
T
E
I
D
N
P
H
Site 190
T2587
R
K
K
L
Y
L
S
T
E
I
D
N
P
H
F
Site 191
T2610
T
M
I
N
F
T
V
T
F
Q
G
L
Q
D
Q
Site 192
S2635
P
H
L
E
D
Q
R
S
K
L
L
E
S
I
S
Site 193
S2642
S
K
L
L
E
S
I
S
L
D
A
I
T
L
E
Site 194
T2647
S
I
S
L
D
A
I
T
L
E
E
L
E
E
K
Site 195
T2675
D
D
D
K
I
V
D
T
L
R
K
S
K
M
T
Site 196
S2679
I
V
D
T
L
R
K
S
K
M
T
S
N
E
I
Site 197
T2682
T
L
R
K
S
K
M
T
S
N
E
I
S
K
R
Site 198
S2683
L
R
K
S
K
M
T
S
N
E
I
S
K
R
I
Site 199
S2687
K
M
T
S
N
E
I
S
K
R
I
E
A
T
K
Site 200
Y2707
I
Q
A
I
R
K
N
Y
L
P
I
A
T
R
G
Site 201
Y2729
A
D
L
T
Q
I
N
Y
M
Y
Q
F
S
L
D
Site 202
S2745
F
H
Q
V
F
V
S
S
V
V
S
K
S
K
E
Site 203
S2748
V
F
V
S
S
V
V
S
K
S
K
E
Q
E
H
Site 204
S2750
V
S
S
V
V
S
K
S
K
E
Q
E
H
S
F
Site 205
S2756
K
S
K
E
Q
E
H
S
F
K
R
E
K
V
S
Site 206
S2763
S
F
K
R
E
K
V
S
P
K
E
V
H
E
F
Site 207
S2772
K
E
V
H
E
F
I
S
I
S
K
E
P
N
L
Site 208
S2774
V
H
E
F
I
S
I
S
K
E
P
N
L
E
N
Site 209
S2792
L
L
D
K
H
I
K
S
A
I
D
M
L
T
K
Site 210
S2864
I
N
I
K
S
A
L
S
Q
S
R
L
T
S
T
Site 211
S2866
I
K
S
A
L
S
Q
S
R
L
T
S
T
F
E
Site 212
T2869
A
L
S
Q
S
R
L
T
S
T
F
E
I
G
E
Site 213
S2870
L
S
Q
S
R
L
T
S
T
F
E
I
G
E
S
Site 214
T2871
S
Q
S
R
L
T
S
T
F
E
I
G
E
S
Q
Site 215
S2877
S
T
F
E
I
G
E
S
Q
H
L
Q
W
L
S
Site 216
Y2893
S
R
W
R
Q
C
Q
Y
V
S
T
H
L
E
P
Site 217
S2913
K
S
L
L
S
N
V
S
Q
W
D
T
F
K
N
Site 218
T2917
S
N
V
S
Q
W
D
T
F
K
N
S
K
A
V
Site 219
Y2925
F
K
N
S
K
A
V
Y
S
L
I
S
T
P
F
Site 220
S2926
K
N
S
K
A
V
Y
S
L
I
S
T
P
F
S
Site 221
S2929
K
A
V
Y
S
L
I
S
T
P
F
S
S
E
N
Site 222
S2933
S
L
I
S
T
P
F
S
S
E
N
A
S
L
E
Site 223
S2934
L
I
S
T
P
F
S
S
E
N
A
S
L
E
E
Site 224
S2938
P
F
S
S
E
N
A
S
L
E
E
N
T
K
P
Site 225
T2951
K
P
P
E
E
K
H
T
F
C
L
L
L
R
A
Site 226
T2976
V
G
R
G
Q
W
L
T
S
T
A
C
D
R
H
Site 227
T2978
R
G
Q
W
L
T
S
T
A
C
D
R
H
T
D
Site 228
T2984
S
T
A
C
D
R
H
T
D
V
C
S
F
S
F
Site 229
S2988
D
R
H
T
D
V
C
S
F
S
F
A
L
N
D
Site 230
Y3008
E
H
V
Q
D
I
F
Y
G
H
C
V
D
K
Y
Site 231
Y3015
Y
G
H
C
V
D
K
Y
H
V
K
V
L
R
P
Site 232
S3024
V
K
V
L
R
P
E
S
L
N
N
S
V
R
K
Site 233
S3028
R
P
E
S
L
N
N
S
V
R
K
F
I
T
E
Site 234
Y3041
T
E
K
M
G
N
K
Y
L
Q
R
T
G
V
N
Site 235
Y3053
G
V
N
L
K
D
A
Y
K
G
S
N
A
R
T
Site 236
S3056
L
K
D
A
Y
K
G
S
N
A
R
T
P
L
I
Site 237
T3060
Y
K
G
S
N
A
R
T
P
L
I
L
I
Q
T
Site 238
T3105
A
I
R
S
C
W
E
T
Q
G
E
K
F
I
E
Site 239
T3162
K
E
E
I
A
V
G
T
P
S
T
L
K
S
M
Site 240
S3168
G
T
P
S
T
L
K
S
M
M
S
S
S
I
W
Site 241
S3171
S
T
L
K
S
M
M
S
S
S
I
W
E
S
L
Site 242
S3172
T
L
K
S
M
M
S
S
S
I
W
E
S
L
S
Site 243
S3173
L
K
S
M
M
S
S
S
I
W
E
S
L
S
K
Site 244
S3177
M
S
S
S
I
W
E
S
L
S
K
N
L
K
D
Site 245
S3179
S
S
I
W
E
S
L
S
K
N
L
K
D
H
D
Site 246
S3238
E
L
E
E
I
F
N
S
F
L
N
M
R
V
P
Site 247
Y3253
T
L
W
Q
K
H
A
Y
R
S
C
K
P
L
S
Site 248
S3260
Y
R
S
C
K
P
L
S
S
W
I
D
D
L
I
Site 249
S3261
R
S
C
K
P
L
S
S
W
I
D
D
L
I
Q
Site 250
Y3288
Y
T
A
I
Q
R
R
Y
M
R
F
V
T
V
W
Site 251
T3293
R
R
Y
M
R
F
V
T
V
W
K
Q
S
I
P
Site 252
T3302
W
K
Q
S
I
P
S
T
S
Q
K
C
K
H
P
Site 253
S3303
K
Q
S
I
P
S
T
S
Q
K
C
K
H
P
E
Site 254
S3312
K
C
K
H
P
E
D
S
E
N
N
F
F
E
G
Site 255
S3389
V
R
R
A
F
K
G
S
A
S
S
H
T
G
V
Site 256
S3391
R
A
F
K
G
S
A
S
S
H
T
G
V
Y
I
Site 257
S3418
E
Q
K
I
L
E
D
S
L
P
L
E
M
C
C
Site 258
S3438
Y
F
L
P
T
K
I
S
T
K
T
P
N
A
S
Site 259
T3441
P
T
K
I
S
T
K
T
P
N
A
S
N
Q
T
Site 260
Y3460
Y
A
F
E
C
P
V
Y
Q
T
P
E
R
S
R
Site 261
T3462
F
E
C
P
V
Y
Q
T
P
E
R
S
R
I
L
Site 262
S3481
L
P
T
N
F
L
T
S
V
Y
L
S
T
K
K
Site 263
Y3483
T
N
F
L
T
S
V
Y
L
S
T
K
K
P
P
Site 264
S3485
F
L
T
S
V
Y
L
S
T
K
K
P
P
S
H
Site 265
S3491
L
S
T
K
K
P
P
S
H
W
I
T
M
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation