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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC15
Full Name:
Coiled-coil domain-containing protein 15
Alias:
Type:
Mass (Da):
110484
Number AA:
951
UniProt ID:
Q0P6D6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
A
R
K
K
P
R
N
T
S
R
L
P
L
A
L
Site 2
S14
R
K
K
P
R
N
T
S
R
L
P
L
A
L
N
Site 3
S50
G
A
W
V
E
P
A
S
P
G
S
S
E
I
P
Site 4
S54
E
P
A
S
P
G
S
S
E
I
P
A
Y
T
S
Site 5
Y59
G
S
S
E
I
P
A
Y
T
S
A
Y
L
I
E
Site 6
Y89
H
F
Q
K
Q
V
K
Y
R
V
N
Q
Q
I
R
Site 7
S106
K
K
Q
Q
L
Q
K
S
Y
E
R
A
Q
K
E
Site 8
S115
E
R
A
Q
K
E
G
S
I
A
M
Q
S
S
A
Site 9
S121
G
S
I
A
M
Q
S
S
A
T
H
L
T
S
K
Site 10
T123
I
A
M
Q
S
S
A
T
H
L
T
S
K
R
T
Site 11
S127
S
S
A
T
H
L
T
S
K
R
T
S
V
F
P
Site 12
S131
H
L
T
S
K
R
T
S
V
F
P
N
N
L
N
Site 13
S149
G
S
S
R
L
P
P
S
L
M
P
G
D
G
I
Site 14
S174
Q
Q
Q
A
Q
A
L
S
E
T
M
K
Q
A
R
Site 15
S186
Q
A
R
H
R
L
A
S
F
K
T
V
I
K
K
Site 16
T189
H
R
L
A
S
F
K
T
V
I
K
K
K
G
S
Site 17
S196
T
V
I
K
K
K
G
S
V
F
P
D
D
G
R
Site 18
S205
F
P
D
D
G
R
K
S
F
L
T
R
E
E
V
Site 19
T208
D
G
R
K
S
F
L
T
R
E
E
V
L
S
R
Site 20
S214
L
T
R
E
E
V
L
S
R
K
P
A
S
T
G
Site 21
S219
V
L
S
R
K
P
A
S
T
G
I
N
T
G
I
Site 22
T220
L
S
R
K
P
A
S
T
G
I
N
T
G
I
R
Site 23
Y244
G
L
L
A
A
V
P
Y
Q
N
Y
M
E
N
Q
Site 24
Y255
M
E
N
Q
E
L
D
Y
E
E
P
D
Y
E
E
Site 25
Y260
L
D
Y
E
E
P
D
Y
E
E
S
S
S
L
V
Site 26
S265
P
D
Y
E
E
S
S
S
L
V
T
D
E
K
G
Site 27
T268
E
E
S
S
S
L
V
T
D
E
K
G
K
E
D
Site 28
S297
E
D
K
N
K
P
F
S
R
V
Q
K
V
K
F
Site 29
Y335
I
L
P
E
A
Q
D
Y
F
L
E
A
Q
G
D
Site 30
T351
L
E
T
Q
G
D
L
T
G
I
Q
S
V
K
P
Site 31
S355
G
D
L
T
G
I
Q
S
V
K
P
D
T
Q
A
Site 32
T360
I
Q
S
V
K
P
D
T
Q
A
V
E
M
K
V
Site 33
T386
P
E
G
Q
P
I
K
T
E
T
Q
G
I
M
L
Site 34
S397
G
I
M
L
K
A
Q
S
I
E
L
E
E
G
S
Site 35
T409
E
G
S
I
V
L
K
T
Q
D
F
L
P
T
N
Site 36
T421
P
T
N
Q
A
L
L
T
K
N
Q
D
V
L
L
Site 37
S439
C
V
L
P
K
D
Q
S
I
L
L
K
Y
Q
D
Site 38
Y444
D
Q
S
I
L
L
K
Y
Q
D
Q
D
F
L
P
Site 39
Y467
D
Q
D
I
L
P
K
Y
Q
D
Q
N
F
L
P
Site 40
Y527
D
Q
N
I
L
P
K
Y
Q
G
Q
D
F
L
P
Site 41
S541
P
K
D
Q
D
F
L
S
R
D
Q
H
V
L
P
Site 42
Y592
F
L
P
R
D
Q
G
Y
L
P
K
D
Q
N
I
Site 43
S617
P
R
D
L
H
V
L
S
N
D
Q
N
I
L
P
Site 44
Y635
D
Q
D
F
L
P
K
Y
Q
K
V
H
F
K
E
Site 45
S645
V
H
F
K
E
P
Y
S
D
M
T
D
E
K
G
Site 46
T648
K
E
P
Y
S
D
M
T
D
E
K
G
R
E
D
Site 47
S657
E
K
G
R
E
D
F
S
L
A
D
Y
Q
C
L
Site 48
Y661
E
D
F
S
L
A
D
Y
Q
C
L
P
P
K
S
Site 49
S668
Y
Q
C
L
P
P
K
S
Q
D
Q
D
D
I
K
Site 50
S681
I
K
N
Q
Q
P
A
S
F
M
R
E
E
R
V
Site 51
Y696
R
E
E
L
P
L
D
Y
H
Q
Y
V
V
P
K
Site 52
Y699
L
P
L
D
Y
H
Q
Y
V
V
P
K
I
Q
D
Site 53
S709
P
K
I
Q
D
Q
D
S
P
R
E
Q
N
K
H
Site 54
S722
K
H
I
K
L
P
S
S
F
E
K
W
E
I
A
Site 55
T733
W
E
I
A
R
G
N
T
P
G
V
P
L
A
Y
Site 56
Y740
T
P
G
V
P
L
A
Y
D
R
Y
Q
S
G
L
Site 57
Y743
V
P
L
A
Y
D
R
Y
Q
S
G
L
S
T
E
Site 58
S745
L
A
Y
D
R
Y
Q
S
G
L
S
T
E
F
Q
Site 59
T749
R
Y
Q
S
G
L
S
T
E
F
Q
A
P
L
A
Site 60
S759
Q
A
P
L
A
F
Q
S
D
V
D
K
E
E
D
Site 61
Y774
K
K
E
R
Q
K
Q
Y
L
R
H
R
R
L
F
Site 62
Y814
K
K
R
E
Q
E
C
Y
A
A
E
Q
R
I
L
Site 63
Y830
M
N
F
H
E
D
P
Y
S
G
E
K
L
S
E
Site 64
S831
N
F
H
E
D
P
Y
S
G
E
K
L
S
E
I
Site 65
S836
P
Y
S
G
E
K
L
S
E
I
L
A
Q
L
Q
Site 66
Y860
K
Q
Q
R
E
K
E
Y
L
R
Y
V
E
A
L
Site 67
Y863
R
E
K
E
Y
L
R
Y
V
E
A
L
R
A
Q
Site 68
Y878
I
Q
E
K
M
Q
L
Y
N
I
T
L
P
P
L
Site 69
Y913
F
Y
K
N
H
R
A
Y
T
R
A
L
H
S
F
Site 70
S923
A
L
H
S
F
I
N
S
C
D
V
P
G
G
N
Site 71
T932
D
V
P
G
G
N
S
T
L
R
V
A
I
H
N
Site 72
S942
V
A
I
H
N
F
A
S
A
H
R
R
T
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation