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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C17orf74
Full Name:
Uncharacterized protein C17orf74
Alias:
Type:
Mass (Da):
57131
Number AA:
501
UniProt ID:
Q0P670
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
T
V
R
C
C
N
Q
Y
Q
E
S
P
H
D
A
Site 2
S71
Q
K
N
E
I
Q
A
S
E
S
P
P
S
G
P
Site 3
S73
N
E
I
Q
A
S
E
S
P
P
S
G
P
P
D
Site 4
S76
Q
A
S
E
S
P
P
S
G
P
P
D
K
A
Q
Site 5
S99
D
P
V
Q
V
K
M
S
R
P
T
Q
Y
S
S
Site 6
T102
Q
V
K
M
S
R
P
T
Q
Y
S
S
F
S
C
Site 7
Y104
K
M
S
R
P
T
Q
Y
S
S
F
S
C
H
H
Site 8
S106
S
R
P
T
Q
Y
S
S
F
S
C
H
H
F
S
Site 9
S117
H
H
F
S
N
H
H
S
S
S
L
L
R
C
V
Site 10
S119
F
S
N
H
H
S
S
S
L
L
R
C
V
R
R
Site 11
S156
R
Q
I
P
H
S
H
S
V
F
R
N
P
H
R
Site 12
S164
V
F
R
N
P
H
R
S
Q
K
M
S
Q
L
H
Site 13
S168
P
H
R
S
Q
K
M
S
Q
L
H
R
V
P
F
Site 14
S183
F
D
Q
E
D
P
D
S
Y
L
E
E
E
D
N
Site 15
Y184
D
Q
E
D
P
D
S
Y
L
E
E
E
D
N
L
Site 16
Y195
E
D
N
L
P
F
P
Y
P
K
Y
P
R
R
G
Site 17
Y198
L
P
F
P
Y
P
K
Y
P
R
R
G
W
G
G
Site 18
Y207
R
R
G
W
G
G
F
Y
Q
R
A
G
L
P
S
Site 19
S214
Y
Q
R
A
G
L
P
S
N
V
G
L
W
G
H
Site 20
Y235
S
L
P
P
P
S
L
Y
L
S
P
E
L
R
C
Site 21
S237
P
P
P
S
L
Y
L
S
P
E
L
R
C
M
P
Site 22
S251
P
K
R
V
E
A
R
S
E
L
R
L
Q
S
Y
Site 23
S257
R
S
E
L
R
L
Q
S
Y
G
R
H
G
S
Q
Site 24
Y258
S
E
L
R
L
Q
S
Y
G
R
H
G
S
Q
S
Site 25
S263
Q
S
Y
G
R
H
G
S
Q
S
R
L
W
G
N
Site 26
S265
Y
G
R
H
G
S
Q
S
R
L
W
G
N
V
E
Site 27
S278
V
E
A
E
Q
W
A
S
S
P
P
P
P
H
R
Site 28
S279
E
A
E
Q
W
A
S
S
P
P
P
P
H
R
L
Site 29
S291
H
R
L
P
P
N
P
S
W
V
P
V
G
H
S
Site 30
S298
S
W
V
P
V
G
H
S
P
Y
P
S
V
G
W
Site 31
Y308
P
S
V
G
W
M
L
Y
D
S
W
D
Q
R
R
Site 32
T318
W
D
Q
R
R
R
G
T
E
G
F
E
R
P
P
Site 33
S327
G
F
E
R
P
P
A
S
V
S
R
N
A
R
P
Site 34
S329
E
R
P
P
A
S
V
S
R
N
A
R
P
E
A
Site 35
S344
Q
G
C
R
E
H
H
S
P
Q
S
H
Q
Q
S
Site 36
S347
R
E
H
H
S
P
Q
S
H
Q
Q
S
L
L
G
Site 37
S351
S
P
Q
S
H
Q
Q
S
L
L
G
H
A
Y
G
Site 38
S360
L
G
H
A
Y
G
Q
S
H
R
S
P
H
P
S
Site 39
S363
A
Y
G
Q
S
H
R
S
P
H
P
S
T
E
P
Site 40
S367
S
H
R
S
P
H
P
S
T
E
P
L
G
Y
S
Site 41
T368
H
R
S
P
H
P
S
T
E
P
L
G
Y
S
S
Site 42
Y373
P
S
T
E
P
L
G
Y
S
S
Q
D
P
R
E
Site 43
S375
T
E
P
L
G
Y
S
S
Q
D
P
R
E
V
R
Site 44
S411
L
T
V
L
D
E
A
S
H
Q
R
T
P
A
P
Site 45
T415
D
E
A
S
H
Q
R
T
P
A
P
S
S
V
L
Site 46
S419
H
Q
R
T
P
A
P
S
S
V
L
V
P
H
S
Site 47
S420
Q
R
T
P
A
P
S
S
V
L
V
P
H
S
S
Site 48
S426
S
S
V
L
V
P
H
S
S
Q
P
W
P
K
V
Site 49
S427
S
V
L
V
P
H
S
S
Q
P
W
P
K
V
Q
Site 50
T443
A
D
P
A
P
P
P
T
M
F
V
P
L
S
R
Site 51
S449
P
T
M
F
V
P
L
S
R
N
P
G
G
N
A
Site 52
Y458
N
P
G
G
N
A
N
Y
Q
V
Y
D
S
L
E
Site 53
Y461
G
N
A
N
Y
Q
V
Y
D
S
L
E
L
K
R
Site 54
S463
A
N
Y
Q
V
Y
D
S
L
E
L
K
R
Q
V
Site 55
S473
L
K
R
Q
V
Q
K
S
R
A
R
S
S
S
L
Site 56
S477
V
Q
K
S
R
A
R
S
S
S
L
P
P
A
S
Site 57
S478
Q
K
S
R
A
R
S
S
S
L
P
P
A
S
T
Site 58
S479
K
S
R
A
R
S
S
S
L
P
P
A
S
T
S
Site 59
S484
S
S
S
L
P
P
A
S
T
S
T
L
R
P
S
Site 60
T485
S
S
L
P
P
A
S
T
S
T
L
R
P
S
L
Site 61
S486
S
L
P
P
A
S
T
S
T
L
R
P
S
L
H
Site 62
T487
L
P
P
A
S
T
S
T
L
R
P
S
L
H
R
Site 63
S491
S
T
S
T
L
R
P
S
L
H
R
S
Q
T
E
Site 64
S495
L
R
P
S
L
H
R
S
Q
T
E
K
L
N
_
Site 65
T497
P
S
L
H
R
S
Q
T
E
K
L
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation