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Updated November 2019
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Protein Info
Short Name:
EP300
Full Name:
Histone acetyltransferase p300
Alias:
300 kd E1A-Binding protein gene; E1A binding protein p300; E1A-associated protein p300; Histone acetyltransferase p300; KAT3B; P300; P300 transcription coactivator homolog
Type:
Transcription, coactivator/corepressor; EC 2.3.1.48; Acetyltransferase; Nuclear receptor co-regulator
Mass (Da):
264161
Number AA:
2414
UniProt ID:
Q09472
International Prot ID:
IPI00020985
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0004402
GO:0008022
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0018076
GO:0006915
GO:0007049
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
V
V
E
P
G
P
P
S
A
K
R
P
K
L
S
Site 2
S19
S
A
K
R
P
K
L
S
S
P
A
L
S
A
S
Site 3
S20
A
K
R
P
K
L
S
S
P
A
L
S
A
S
A
Site 4
S24
K
L
S
S
P
A
L
S
A
S
A
S
D
G
T
Site 5
S26
S
S
P
A
L
S
A
S
A
S
D
G
T
D
F
Site 6
S28
P
A
L
S
A
S
A
S
D
G
T
D
F
G
S
Site 7
T31
S
A
S
A
S
D
G
T
D
F
G
S
L
F
D
Site 8
S35
S
D
G
T
D
F
G
S
L
F
D
L
E
H
D
Site 9
S50
L
P
D
E
L
I
N
S
T
E
L
G
L
T
N
Site 10
T56
N
S
T
E
L
G
L
T
N
G
G
D
I
N
Q
Site 11
S76
G
M
V
Q
D
A
A
S
K
H
K
Q
L
S
E
Site 12
S82
A
S
K
H
K
Q
L
S
E
L
L
R
S
G
S
Site 13
S87
Q
L
S
E
L
L
R
S
G
S
S
P
N
L
N
Site 14
S89
S
E
L
L
R
S
G
S
S
P
N
L
N
M
G
Site 15
S90
E
L
L
R
S
G
S
S
P
N
L
N
M
G
V
Site 16
S106
G
P
G
Q
V
M
A
S
Q
A
Q
Q
S
S
P
Site 17
S112
A
S
Q
A
Q
Q
S
S
P
G
L
G
L
I
N
Site 18
T127
S
M
V
K
S
P
M
T
Q
A
G
L
T
S
P
Site 19
S133
M
T
Q
A
G
L
T
S
P
N
M
G
M
G
T
Site 20
T140
S
P
N
M
G
M
G
T
S
G
P
N
Q
G
P
Site 21
S141
P
N
M
G
M
G
T
S
G
P
N
Q
G
P
T
Site 22
T148
S
G
P
N
Q
G
P
T
Q
S
T
G
M
M
N
Site 23
S150
P
N
Q
G
P
T
Q
S
T
G
M
M
N
S
P
Site 24
S156
Q
S
T
G
M
M
N
S
P
V
N
Q
P
A
M
Site 25
S195
P
N
Q
V
M
N
G
S
I
G
A
G
R
G
R
Site 26
Y207
R
G
R
Q
N
M
Q
Y
P
N
P
G
M
G
S
Site 27
S227
T
E
P
L
Q
Q
G
S
P
Q
M
G
G
Q
T
Site 28
Y253
M
M
N
N
P
N
P
Y
G
S
P
Y
T
Q
N
Site 29
S255
N
N
P
N
P
Y
G
S
P
Y
T
Q
N
P
G
Site 30
Y257
P
N
P
Y
G
S
P
Y
T
Q
N
P
G
Q
Q
Site 31
T258
N
P
Y
G
S
P
Y
T
Q
N
P
G
Q
Q
I
Site 32
S268
P
G
Q
Q
I
G
A
S
G
L
G
L
Q
I
Q
Site 33
T278
G
L
Q
I
Q
T
K
T
V
L
S
N
N
L
S
Site 34
S281
I
Q
T
K
T
V
L
S
N
N
L
S
P
F
A
Site 35
S285
T
V
L
S
N
N
L
S
P
F
A
M
D
K
K
Site 36
T317
V
Q
Q
P
G
L
V
T
P
V
A
Q
G
M
G
Site 37
T329
G
M
G
S
G
A
H
T
A
D
P
E
K
R
K
Site 38
T380
K
N
V
L
N
H
M
T
H
C
Q
S
G
K
S
Site 39
T431
R
N
Q
Q
P
I
L
T
G
A
P
V
G
L
G
Site 40
S441
P
V
G
L
G
N
P
S
S
L
G
V
G
Q
Q
Site 41
S442
V
G
L
G
N
P
S
S
L
G
V
G
Q
Q
S
Site 42
S454
Q
Q
S
A
P
N
L
S
T
V
S
Q
I
D
P
Site 43
T455
Q
S
A
P
N
L
S
T
V
S
Q
I
D
P
S
Site 44
S457
A
P
N
L
S
T
V
S
Q
I
D
P
S
S
I
Site 45
S463
V
S
Q
I
D
P
S
S
I
E
R
A
Y
A
A
Site 46
Y468
P
S
S
I
E
R
A
Y
A
A
L
G
L
P
Y
Site 47
S499
Q
N
Q
Q
P
G
Q
S
P
Q
G
M
R
P
M
Site 48
S507
P
Q
G
M
R
P
M
S
N
M
S
A
S
P
M
Site 49
S510
M
R
P
M
S
N
M
S
A
S
P
M
G
V
N
Site 50
S512
P
M
S
N
M
S
A
S
P
M
G
V
N
G
G
Site 51
T524
N
G
G
V
G
V
Q
T
P
S
L
L
S
D
S
Site 52
S529
V
Q
T
P
S
L
L
S
D
S
M
L
H
S
A
Site 53
S535
L
S
D
S
M
L
H
S
A
I
N
S
Q
N
P
Site 54
S539
M
L
H
S
A
I
N
S
Q
N
P
M
M
S
E
Site 55
S545
N
S
Q
N
P
M
M
S
E
N
A
S
V
P
S
Site 56
S549
P
M
M
S
E
N
A
S
V
P
S
L
G
P
M
Site 57
S552
S
E
N
A
S
V
P
S
L
G
P
M
P
T
A
Site 58
T558
P
S
L
G
P
M
P
T
A
A
Q
P
S
T
T
Site 59
Y611
R
M
E
N
L
V
A
Y
A
R
K
V
E
G
D
Site 60
Y620
R
K
V
E
G
D
M
Y
E
S
A
N
N
R
A
Site 61
S622
V
E
G
D
M
Y
E
S
A
N
N
R
A
E
Y
Site 62
Y629
S
A
N
N
R
A
E
Y
Y
H
L
L
A
E
K
Site 63
Y630
A
N
N
R
A
E
Y
Y
H
L
L
A
E
K
I
Site 64
Y638
H
L
L
A
E
K
I
Y
K
I
Q
K
E
L
E
Site 65
T650
E
L
E
E
K
R
R
T
R
L
Q
K
Q
N
M
Site 66
S684
Q
P
Q
P
G
M
T
S
N
G
P
L
P
D
P
Site 67
S692
N
G
P
L
P
D
P
S
M
I
R
G
S
V
P
Site 68
S697
D
P
S
M
I
R
G
S
V
P
N
Q
M
M
P
Site 69
T707
N
Q
M
M
P
R
I
T
P
Q
S
G
L
N
Q
Site 70
S710
M
P
R
I
T
P
Q
S
G
L
N
Q
F
G
Q
Site 71
T730
P
P
I
V
P
R
Q
T
P
P
L
Q
H
H
G
Site 72
S759
G
P
R
M
Q
Q
P
S
N
Q
G
Q
F
L
P
Site 73
T768
Q
G
Q
F
L
P
Q
T
Q
F
P
S
Q
G
M
Site 74
S772
L
P
Q
T
Q
F
P
S
Q
G
M
N
V
T
N
Site 75
S786
N
I
P
L
A
P
S
S
G
Q
A
P
V
S
Q
Site 76
S792
S
S
G
Q
A
P
V
S
Q
A
Q
M
S
S
S
Site 77
S797
P
V
S
Q
A
Q
M
S
S
S
S
C
P
V
N
Site 78
S798
V
S
Q
A
Q
M
S
S
S
S
C
P
V
N
S
Site 79
S799
S
Q
A
Q
M
S
S
S
S
C
P
V
N
S
P
Site 80
S800
Q
A
Q
M
S
S
S
S
C
P
V
N
S
P
I
Site 81
S805
S
S
S
C
P
V
N
S
P
I
M
P
P
G
S
Site 82
S812
S
P
I
M
P
P
G
S
Q
G
S
H
I
H
C
Site 83
S815
M
P
P
G
S
Q
G
S
H
I
H
C
P
Q
L
Site 84
S831
Q
P
A
L
H
Q
N
S
P
S
P
V
P
S
R
Site 85
S833
A
L
H
Q
N
S
P
S
P
V
P
S
R
T
P
Site 86
S837
N
S
P
S
P
V
P
S
R
T
P
T
P
H
H
Site 87
T839
P
S
P
V
P
S
R
T
P
T
P
H
H
T
P
Site 88
T841
P
V
P
S
R
T
P
T
P
H
H
T
P
P
S
Site 89
T845
R
T
P
T
P
H
H
T
P
P
S
I
G
A
Q
Site 90
S848
T
P
H
H
T
P
P
S
I
G
A
Q
Q
P
P
Site 91
T857
G
A
Q
Q
P
P
A
T
T
I
P
A
P
V
P
Site 92
S875
A
M
P
P
G
P
Q
S
Q
A
L
H
P
P
P
Site 93
T885
L
H
P
P
P
R
Q
T
P
T
P
P
T
T
Q
Site 94
T887
P
P
P
R
Q
T
P
T
P
P
T
T
Q
L
P
Site 95
T891
Q
T
P
T
P
P
T
T
Q
L
P
Q
Q
V
Q
Site 96
S900
L
P
Q
Q
V
Q
P
S
L
P
A
A
P
S
A
Site 97
S906
P
S
L
P
A
A
P
S
A
D
Q
P
Q
Q
Q
Site 98
S916
Q
P
Q
Q
Q
P
R
S
Q
Q
S
T
A
A
S
Site 99
S919
Q
Q
P
R
S
Q
Q
S
T
A
A
S
V
P
T
Site 100
T920
Q
P
R
S
Q
Q
S
T
A
A
S
V
P
T
P
Site 101
S923
S
Q
Q
S
T
A
A
S
V
P
T
P
T
A
P
Site 102
T938
L
L
P
P
Q
P
A
T
P
L
S
Q
P
A
V
Site 103
S941
P
Q
P
A
T
P
L
S
Q
P
A
V
S
I
E
Site 104
S946
P
L
S
Q
P
A
V
S
I
E
G
Q
V
S
N
Site 105
S952
V
S
I
E
G
Q
V
S
N
P
P
S
T
S
S
Site 106
S956
G
Q
V
S
N
P
P
S
T
S
S
T
E
V
N
Site 107
S958
V
S
N
P
P
S
T
S
S
T
E
V
N
S
Q
Site 108
S959
S
N
P
P
S
T
S
S
T
E
V
N
S
Q
A
Site 109
T960
N
P
P
S
T
S
S
T
E
V
N
S
Q
A
I
Site 110
S973
A
I
A
E
K
Q
P
S
Q
E
V
K
M
E
A
Site 111
T992
D
Q
P
E
P
A
D
T
Q
P
E
D
I
S
E
Site 112
S998
D
T
Q
P
E
D
I
S
E
S
K
V
E
D
C
Site 113
T1012
C
K
M
E
S
T
E
T
E
E
R
S
T
E
L
Site 114
T1017
T
E
T
E
E
R
S
T
E
L
K
T
E
I
K
Site 115
S1031
K
E
E
E
D
Q
P
S
T
S
A
T
Q
S
S
Site 116
S1033
E
E
D
Q
P
S
T
S
A
T
Q
S
S
P
A
Site 117
T1035
D
Q
P
S
T
S
A
T
Q
S
S
P
A
P
G
Site 118
S1037
P
S
T
S
A
T
Q
S
S
P
A
P
G
Q
S
Site 119
S1038
S
T
S
A
T
Q
S
S
P
A
P
G
Q
S
K
Site 120
S1044
S
S
P
A
P
G
Q
S
K
K
K
I
F
K
P
Site 121
S1072
L
Y
R
Q
D
P
E
S
L
P
F
R
Q
P
V
Site 122
S1095
D
Y
F
D
I
V
K
S
P
M
D
L
S
T
I
Site 123
S1100
V
K
S
P
M
D
L
S
T
I
K
R
K
L
D
Site 124
T1101
K
S
P
M
D
L
S
T
I
K
R
K
L
D
T
Site 125
Y1111
R
K
L
D
T
G
Q
Y
Q
E
P
W
Q
Y
V
Site 126
Y1131
M
F
N
N
A
W
L
Y
N
R
K
T
S
R
V
Site 127
T1135
A
W
L
Y
N
R
K
T
S
R
V
Y
K
Y
C
Site 128
Y1139
N
R
K
T
S
R
V
Y
K
Y
C
S
K
L
S
Site 129
Y1141
K
T
S
R
V
Y
K
Y
C
S
K
L
S
E
V
Site 130
S1146
Y
K
Y
C
S
K
L
S
E
V
F
E
Q
E
I
Site 131
T1174
K
L
E
F
S
P
Q
T
L
C
C
Y
G
K
Q
Site 132
Y1191
T
I
P
R
D
A
T
Y
Y
S
Y
Q
N
R
Y
Site 133
Y1192
I
P
R
D
A
T
Y
Y
S
Y
Q
N
R
Y
H
Site 134
Y1194
R
D
A
T
Y
Y
S
Y
Q
N
R
Y
H
F
C
Site 135
S1214
E
I
Q
G
E
S
V
S
L
G
D
D
P
S
Q
Site 136
S1220
V
S
L
G
D
D
P
S
Q
P
Q
T
T
I
N
Site 137
T1224
D
D
P
S
Q
P
Q
T
T
I
N
K
E
Q
F
Site 138
S1232
T
I
N
K
E
Q
F
S
K
R
K
N
D
T
L
Site 139
T1238
F
S
K
R
K
N
D
T
L
D
P
E
L
F
V
Site 140
S1279
C
D
G
C
L
K
K
S
A
R
T
R
K
E
N
Site 141
S1289
T
R
K
E
N
K
F
S
A
K
R
L
P
S
T
Site 142
S1295
F
S
A
K
R
L
P
S
T
R
L
G
T
F
L
Site 143
T1296
S
A
K
R
L
P
S
T
R
L
G
T
F
L
E
Site 144
T1300
L
P
S
T
R
L
G
T
F
L
E
N
R
V
N
Site 145
S1318
R
R
Q
N
H
P
E
S
G
E
V
T
V
R
V
Site 146
T1322
H
P
E
S
G
E
V
T
V
R
V
V
H
A
S
Site 147
S1329
T
V
R
V
V
H
A
S
D
K
T
V
E
V
K
Site 148
T1332
V
V
H
A
S
D
K
T
V
E
V
K
P
G
M
Site 149
S1346
M
K
A
R
F
V
D
S
G
E
M
A
E
S
F
Site 150
S1352
D
S
G
E
M
A
E
S
F
P
Y
R
T
K
A
Site 151
Y1355
E
M
A
E
S
F
P
Y
R
T
K
A
L
F
A
Site 152
Y1381
F
G
M
H
V
Q
E
Y
G
S
D
C
P
P
P
Site 153
Y1394
P
P
N
Q
R
R
V
Y
I
S
Y
L
D
S
V
Site 154
S1396
N
Q
R
R
V
Y
I
S
Y
L
D
S
V
H
F
Site 155
Y1397
Q
R
R
V
Y
I
S
Y
L
D
S
V
H
F
F
Site 156
Y1414
K
C
L
R
T
A
V
Y
H
E
I
L
I
G
Y
Site 157
Y1421
Y
H
E
I
L
I
G
Y
L
E
Y
V
K
K
L
Site 158
Y1424
I
L
I
G
Y
L
E
Y
V
K
K
L
G
Y
T
Site 159
Y1446
P
P
S
E
G
D
D
Y
I
F
H
C
H
P
P
Site 160
Y1467
P
K
R
L
Q
E
W
Y
K
K
M
L
D
K
A
Site 161
S1476
K
M
L
D
K
A
V
S
E
R
I
V
H
D
Y
Site 162
Y1483
S
E
R
I
V
H
D
Y
K
D
I
F
K
Q
A
Site 163
T1491
K
D
I
F
K
Q
A
T
E
D
R
L
T
S
A
Site 164
T1496
Q
A
T
E
D
R
L
T
S
A
K
E
L
P
Y
Site 165
S1497
A
T
E
D
R
L
T
S
A
K
E
L
P
Y
F
Site 166
Y1503
T
S
A
K
E
L
P
Y
F
E
G
D
F
W
P
Site 167
T1533
E
R
K
R
E
E
N
T
S
N
E
S
T
D
V
Site 168
S1534
R
K
R
E
E
N
T
S
N
E
S
T
D
V
T
Site 169
T1538
E
N
T
S
N
E
S
T
D
V
T
K
G
D
S
Site 170
T1541
S
N
E
S
T
D
V
T
K
G
D
S
K
N
A
Site 171
T1556
K
K
K
N
N
K
K
T
S
K
N
K
S
S
L
Site 172
S1557
K
K
N
N
K
K
T
S
K
N
K
S
S
L
S
Site 173
S1561
K
K
T
S
K
N
K
S
S
L
S
R
G
N
K
Site 174
S1562
K
T
S
K
N
K
S
S
L
S
R
G
N
K
K
Site 175
S1577
K
P
G
M
P
N
V
S
N
D
L
S
Q
K
L
Site 176
S1581
P
N
V
S
N
D
L
S
Q
K
L
Y
A
T
M
Site 177
Y1585
N
D
L
S
Q
K
L
Y
A
T
M
E
K
H
K
Site 178
T1632
D
G
R
D
A
F
L
T
L
A
R
D
K
H
L
Site 179
S1642
R
D
K
H
L
E
F
S
S
L
R
R
A
Q
W
Site 180
S1643
D
K
H
L
E
F
S
S
L
R
R
A
Q
W
S
Site 181
S1662
L
V
E
L
H
T
Q
S
Q
D
R
F
V
Y
T
Site 182
Y1668
Q
S
Q
D
R
F
V
Y
T
C
N
E
C
K
H
Site 183
S1716
G
L
G
L
D
D
E
S
N
N
Q
Q
A
A
A
Site 184
T1724
N
N
Q
Q
A
A
A
T
Q
S
P
G
D
S
R
Site 185
S1726
Q
Q
A
A
A
T
Q
S
P
G
D
S
R
R
L
Site 186
S1730
A
T
Q
S
P
G
D
S
R
R
L
S
I
Q
R
Site 187
S1734
P
G
D
S
R
R
L
S
I
Q
R
C
I
Q
S
Site 188
T1775
T
K
G
C
K
R
K
T
N
G
G
C
P
I
C
Site 189
S1834
M
L
R
R
R
M
A
S
M
Q
R
T
G
V
V
Site 190
T1838
R
M
A
S
M
Q
R
T
G
V
V
G
Q
Q
Q
Site 191
S1849
G
Q
Q
Q
G
L
P
S
P
T
P
A
T
P
T
Site 192
T1851
Q
Q
G
L
P
S
P
T
P
A
T
P
T
T
P
Site 193
T1854
L
P
S
P
T
P
A
T
P
T
T
P
T
G
Q
Site 194
T1857
P
T
P
A
T
P
T
T
P
T
G
Q
Q
P
T
Site 195
T1865
P
T
G
Q
Q
P
T
T
P
Q
T
P
Q
P
T
Site 196
T1868
Q
Q
P
T
T
P
Q
T
P
Q
P
T
S
Q
P
Site 197
S1873
P
Q
T
P
Q
P
T
S
Q
P
Q
P
T
P
P
Site 198
T1878
P
T
S
Q
P
Q
P
T
P
P
N
S
M
P
P
Site 199
S1882
P
Q
P
T
P
P
N
S
M
P
P
Y
L
P
R
Site 200
Y1886
P
P
N
S
M
P
P
Y
L
P
R
T
Q
A
A
Site 201
T1890
M
P
P
Y
L
P
R
T
Q
A
A
G
P
V
S
Site 202
S1897
T
Q
A
A
G
P
V
S
Q
G
K
A
A
G
Q
Site 203
T1906
G
K
A
A
G
Q
V
T
P
P
T
P
P
Q
T
Site 204
T1909
A
G
Q
V
T
P
P
T
P
P
Q
T
A
Q
P
Site 205
T1913
T
P
P
T
P
P
Q
T
A
Q
P
P
L
P
G
Site 206
T1938
Q
I
Q
R
A
A
E
T
Q
R
Q
M
A
H
V
Site 207
T1960
Q
H
Q
M
P
P
M
T
P
M
A
P
M
G
M
Site 208
T1973
G
M
N
P
P
P
M
T
R
G
P
S
G
H
L
Site 209
S1977
P
P
M
T
R
G
P
S
G
H
L
E
P
G
M
Site 210
S1996
M
Q
Q
Q
P
P
W
S
Q
G
G
L
P
Q
P
Site 211
S2008
P
Q
P
Q
Q
L
Q
S
G
M
P
R
P
A
M
Site 212
S2017
M
P
R
P
A
M
M
S
V
A
Q
H
G
Q
P
Site 213
T2045
I
S
P
L
K
P
G
T
V
S
Q
Q
A
L
Q
Site 214
S2047
P
L
K
P
G
T
V
S
Q
Q
A
L
Q
N
L
Site 215
T2057
A
L
Q
N
L
L
R
T
L
R
S
P
S
S
P
Site 216
S2060
N
L
L
R
T
L
R
S
P
S
S
P
L
Q
Q
Site 217
S2062
L
R
T
L
R
S
P
S
S
P
L
Q
Q
Q
Q
Site 218
S2063
R
T
L
R
S
P
S
S
P
L
Q
Q
Q
Q
V
Site 219
Y2092
I
K
Q
R
A
A
K
Y
A
N
S
N
P
Q
P
Site 220
T2117
Q
P
G
L
Q
P
P
T
M
P
G
Q
Q
G
V
Site 221
S2162
Q
P
P
M
G
G
M
S
P
Q
A
Q
Q
M
N
Site 222
Y2219
Q
Q
P
Q
G
V
G
Y
P
P
Q
Q
Q
Q
R
Site 223
S2256
L
G
A
E
A
G
A
S
L
Q
A
Y
Q
Q
R
Site 224
Y2260
A
G
A
S
L
Q
A
Y
Q
Q
R
L
L
Q
Q
Site 225
S2271
L
L
Q
Q
Q
M
G
S
P
V
Q
P
N
P
M
Site 226
S2279
P
V
Q
P
N
P
M
S
P
Q
Q
H
M
L
P
Site 227
S2291
M
L
P
N
Q
A
Q
S
P
H
L
Q
G
Q
Q
Site 228
S2302
Q
G
Q
Q
I
P
N
S
L
S
N
Q
V
R
S
Site 229
S2304
Q
Q
I
P
N
S
L
S
N
Q
V
R
S
P
Q
Site 230
S2309
S
L
S
N
Q
V
R
S
P
Q
P
V
P
S
P
Site 231
S2315
R
S
P
Q
P
V
P
S
P
R
P
Q
S
Q
P
Site 232
S2320
V
P
S
P
R
P
Q
S
Q
P
P
H
S
S
P
Site 233
S2325
P
Q
S
Q
P
P
H
S
S
P
S
P
R
M
Q
Site 234
S2326
Q
S
Q
P
P
H
S
S
P
S
P
R
M
Q
P
Site 235
S2328
Q
P
P
H
S
S
P
S
P
R
M
Q
P
Q
P
Site 236
S2336
P
R
M
Q
P
Q
P
S
P
H
H
V
S
P
Q
Site 237
S2341
Q
P
S
P
H
H
V
S
P
Q
T
S
S
P
H
Site 238
T2344
P
H
H
V
S
P
Q
T
S
S
P
H
P
G
L
Site 239
S2345
H
H
V
S
P
Q
T
S
S
P
H
P
G
L
V
Site 240
S2346
H
V
S
P
Q
T
S
S
P
H
P
G
L
V
A
Site 241
S2366
M
E
Q
G
H
F
A
S
P
D
Q
N
S
M
L
Site 242
S2371
F
A
S
P
D
Q
N
S
M
L
S
Q
L
A
S
Site 243
S2374
P
D
Q
N
S
M
L
S
Q
L
A
S
N
P
G
Site 244
S2396
S
A
T
D
L
G
L
S
T
D
N
S
D
L
N
Site 245
S2400
L
G
L
S
T
D
N
S
D
L
N
S
N
L
S
Site 246
S2404
T
D
N
S
D
L
N
S
N
L
S
Q
S
T
L
Site 247
S2407
S
D
L
N
S
N
L
S
Q
S
T
L
D
I
H
Site 248
S2409
L
N
S
N
L
S
Q
S
T
L
D
I
H
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation