PhosphoNET

           
Protein Info 
   
Short Name:  SFRS4
Full Name:  Serine/arginine-rich splicing factor 4
Alias:  Arginine/serine-rich 4; Pre-mRNA splicing factor SRP75; Pre-mRNA-splicing factor SRP75; SFR4; Splicing factor; SRP001LB; SRP75
Type:  Nuclear speck, Nucleus protein; RNA binding protein
Mass (Da):  56678
Number AA:  494
UniProt ID:  Q08170
International Prot ID:  IPI00000015
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016607  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0003723 PhosphoSite+ KinaseNET
Biological Process:  GO:0000398  GO:0000377  GO:0000398 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10RVYIGRLSYQARERD
Site 2Y11VYIGRLSYQARERDV
Site 3Y25VERFFKGYGKILEVD
Site 4Y53RDADDAVYELNGKDL
Site 5S78RGPRRDGSYGSGRSG
Site 6Y79GPRRDGSYGSGRSGY
Site 7S81RRDGSYGSGRSGYGY
Site 8S84GSYGSGRSGYGYRRS
Site 9Y86YGSGRSGYGYRRSGR
Site 10Y88SGRSGYGYRRSGRDK
Site 11S91SGYGYRRSGRDKYGP
Site 12Y96RRSGRDKYGPPTRTE
Site 13Y104GPPTRTEYRLIVENL
Site 14S112RLIVENLSSRCSWQD
Site 15S113LIVENLSSRCSWQDL
Site 16S116ENLSSRCSWQDLKDY
Site 17Y123SWQDLKDYMRQAGEV
Site 18S149EGVIEFVSYSDMKRA
Site 19S151VIEFVSYSDMKRALE
Site 20T163ALEKLDGTEVNGRKI
Site 21S179LVEDKPGSRRRRSYS
Site 22S184PGSRRRRSYSRSRSH
Site 23Y185GSRRRRSYSRSRSHS
Site 24S186SRRRRSYSRSRSHSR
Site 25S188RRRSYSRSRSHSRSR
Site 26S190RSYSRSRSHSRSRSR
Site 27S192YSRSRSHSRSRSRSR
Site 28S196RSHSRSRSRSRHSRK
Site 29S198HSRSRSRSRHSRKSR
Site 30S201SRSRSRHSRKSRSRS
Site 31S204RSRHSRKSRSRSGSS
Site 32S206RHSRKSRSRSGSSKS
Site 33S208SRKSRSRSGSSKSSH
Site 34S210KSRSRSGSSKSSHSK
Site 35S211SRSRSGSSKSSHSKS
Site 36S213SRSGSSKSSHSKSRS
Site 37S214RSGSSKSSHSKSRSR
Site 38S216GSSKSSHSKSRSRSR
Site 39S218SKSSHSKSRSRSRSG
Site 40S220SSHSKSRSRSRSGSR
Site 41S222HSKSRSRSRSGSRSR
Site 42S224KSRSRSRSGSRSRSK
Site 43S226RSRSRSGSRSRSKSR
Site 44S228RSRSGSRSRSKSRSR
Site 45S230RSGSRSRSKSRSRSQ
Site 46S232GSRSRSKSRSRSQSR
Site 47S234RSRSKSRSRSQSRSR
Site 48S236RSKSRSRSQSRSRSK
Site 49S238KSRSRSQSRSRSKKE
Site 50S240RSRSQSRSRSKKEKS
Site 51S242RSQSRSRSKKEKSRS
Site 52S247SRSKKEKSRSPSKEK
Site 53S249SKKEKSRSPSKEKSR
Site 54S251KEKSRSPSKEKSRSR
Site 55S255RSPSKEKSRSRSHSA
Site 56S257PSKEKSRSRSHSAGK
Site 57S259KEKSRSRSHSAGKSR
Site 58S261KSRSRSHSAGKSRSK
Site 59S265RSHSAGKSRSKSKDQ
Site 60S267HSAGKSRSKSKDQAE
Site 61S269AGKSRSKSKDQAEEK
Site 62S288DNVGKPKSRSPSRHK
Site 63S290VGKPKSRSPSRHKSK
Site 64S292KPKSRSPSRHKSKSK
Site 65S296RSPSRHKSKSKSRSR
Site 66S298PSRHKSKSKSRSRSQ
Site 67S300RHKSKSKSRSRSQER
Site 68S302KSKSKSRSRSQERRV
Site 69S304KSKSRSRSQERRVEE
Site 70S316VEEEKRGSVSRGRSQ
Site 71S318EEKRGSVSRGRSQEK
Site 72S322GSVSRGRSQEKSLRQ
Site 73S326RGRSQEKSLRQSRSR
Site 74S330QEKSLRQSRSRSRSK
Site 75S332KSLRQSRSRSRSKGG
Site 76S334LRQSRSRSRSKGGSR
Site 77S336QSRSRSRSKGGSRSR
Site 78S340RSRSKGGSRSRSRSR
Site 79S342RSKGGSRSRSRSRSK
Site 80S344KGGSRSRSRSRSKSK
Site 81S346GSRSRSRSRSKSKDK
Site 82S348RSRSRSRSKSKDKRK
Site 83S350RSRSRSKSKDKRKGR
Site 84S360KRKGRKRSREESRSR
Site 85S364RKRSREESRSRSRSR
Site 86S366RSREESRSRSRSRSK
Site 87S368REESRSRSRSRSKSE
Site 88S370ESRSRSRSRSKSERS
Site 89S372RSRSRSRSKSERSRK
Site 90S374RSRSRSKSERSRKRG
Site 91S377SRSKSERSRKRGSKR
Site 92S382ERSRKRGSKRDSKAG
Site 93S386KRGSKRDSKAGSSKK
Site 94S390KRDSKAGSSKKKKKE
Site 95S391RDSKAGSSKKKKKED
Site 96T399KKKKKEDTDRSQSRS
Site 97S402KKEDTDRSQSRSPSR
Site 98S404EDTDRSQSRSPSRSV
Site 99S406TDRSQSRSPSRSVSK
Site 100S408RSQSRSPSRSVSKER
Site 101S410QSRSPSRSVSKEREH
Site 102S412RSPSRSVSKEREHAK
Site 103S420KEREHAKSESSQREG
Site 104S422REHAKSESSQREGRG
Site 105S423EHAKSESSQREGRGE
Site 106S431QREGRGESENAGTNQ
Site 107T436GESENAGTNQETRSR
Site 108T440NAGTNQETRSRSRSN
Site 109S442GTNQETRSRSRSNSK
Site 110S444NQETRSRSRSNSKSK
Site 111S446ETRSRSRSNSKSKPN
Site 112S448RSRSRSNSKSKPNLP
Site 113S450RSRSNSKSKPNLPSE
Site 114S456KSKPNLPSESRSRSK
Site 115S458KPNLPSESRSRSKSA
Site 116S460NLPSESRSRSKSASK
Site 117S462PSESRSRSKSASKTR
Site 118S464ESRSRSKSASKTRSR
Site 119S466RSRSKSASKTRSRSK
Site 120T468RSKSASKTRSRSKSR
Site 121S470KSASKTRSRSKSRSR
Site 122S472ASKTRSRSKSRSRSA
Site 123S474KTRSRSKSRSRSASR
Site 124S476RSRSKSRSRSASRSP
Site 125S478RSKSRSRSASRSPSR
Site 126S480KSRSRSASRSPSRSR
Site 127S482RSRSASRSPSRSRSR
Site 128S484RSASRSPSRSRSRSH
Site 129S486ASRSPSRSRSRSHSR
Site 130S488RSPSRSRSRSHSRS_
Site 131S490PSRSRSRSHSRS___
Site 132S492RSRSRSHSRS_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation