PhosphoNET

           
Protein Info 
   
Short Name:  RING1
Full Name:  E3 ubiquitin-protein ligase RING1
Alias:  EC 6.3.2.-; Polycomb complex protein RING1; Ring finger 1; RING finger protein 1; RING1A; RNF1
Type:  PcG protein complex, Ubiquitin ligase complex, Nuclear speck, Nucleolus, Cytoplasm, Nucleus, Sex chromatin protein
Mass (Da):  42429
Number AA:  406
UniProt ID:  Q06587
International Prot ID:  IPI00641330
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000151  GO:0000785  GO:0000790 Uniprot OncoNet
Molecular Function:  GO:0003682  GO:0003824  GO:0004842 PhosphoSite+ KinaseNET
Biological Process:  GO:0003002  GO:0006139  GO:0006325 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T13NAQNASKTWELSLYE
Site 2S17ASKTWELSLYELHRT
Site 3Y19KTWELSLYELHRTPQ
Site 4T24SLYELHRTPQEAIMD
Site 5T33QEAIMDGTEIAVSPR
Site 6S38DGTEIAVSPRSLHSE
Site 7T60DMLKNTMTTKECLHR
Site 8T86SGNKECPTCRKKLVS
Site 9S93TCRKKLVSKRSLRPD
Site 10S96KKLVSKRSLRPDPNF
Site 11Y111DALISKIYPSREEYE
Site 12S113LISKIYPSREEYEAH
Site 13Y117IYPSREEYEAHQDRV
Site 14S129DRVLIRLSRLHNQQA
Site 15S138LHNQQALSSSIEEGL
Site 16S140NQQALSSSIEEGLRM
Site 17S163VRRPIPGSDQTTTMS
Site 18T166PIPGSDQTTTMSGGE
Site 19T167IPGSDQTTTMSGGEG
Site 20T168PGSDQTTTMSGGEGE
Site 21S170SDQTTTMSGGEGEPG
Site 22S187EGDGEDVSSDSAPDS
Site 23S188GDGEDVSSDSAPDSA
Site 24S190GEDVSSDSAPDSAPG
Site 25S194SSDSAPDSAPGPAPK
Site 26S211RGGGAGGSSVGTGGG
Site 27S212GGGAGGSSVGTGGGG
Site 28T215AGGSSVGTGGGGTGG
Site 29T220VGTGGGGTGGVGGGA
Site 30S229GVGGGAGSEDSGDRG
Site 31S232GGAGSEDSGDRGGTL
Site 32T238DSGDRGGTLGGGTLG
Site 33T243GGTLGGGTLGPPSPP
Site 34S248GGTLGPPSPPGAPSP
Site 35S254PSPPGAPSPPEPGGE
Site 36Y278LLVEKGEYCQTRYVK
Site 37T281EKGEYCQTRYVKTTG
Site 38Y283GEYCQTRYVKTTGNA
Site 39T291VKTTGNATVDHLSKY
Site 40S324GGPGGGASDTGGPDG
Site 41T326PGGGASDTGGPDGCG
Site 42S352PEEPALPSLEGVSEK
Site 43Y361EGVSEKQYTIYIAPG
Site 44T362GVSEKQYTIYIAPGG
Site 45Y364SEKQYTIYIAPGGGA
Site 46T380TTLNGSLTLELVNEK
Site 47Y399SRPLELCYAPTKDPK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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