PhosphoNET

           
Protein Info 
   
Short Name:  RUNX1T1
Full Name:  Protein CBFA2T1
Alias:  AML1T1; CBFA2T1; CDR; Core-binding factor, runt domain, alpha subunit 2;translocated to, 1 (ETO); Cyclin-D-related protein; Eight twenty one protein; ETO; MTG8
Type:  Nucleus protein
Mass (Da):  67566
Number AA:  604
UniProt ID:  Q06455
International Prot ID:  IPI00333194
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003700  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0006091  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S13RNTWRALSLVIGDCR
Site 2Y27RKKGNFEYCQDRTEK
Site 3S36QDRTEKHSTMPDSPV
Site 4T37DRTEKHSTMPDSPVD
Site 5S41KHSTMPDSPVDVKTQ
Site 6T47DSPVDVKTQSRLTPP
Site 7T52VKTQSRLTPPTMPPP
Site 8T55QSRLTPPTMPPPPTT
Site 9T61PTMPPPPTTQGAPRT
Site 10T68TTQGAPRTSSFTPTT
Site 11S69TQGAPRTSSFTPTTL
Site 12S70QGAPRTSSFTPTTLT
Site 13T72APRTSSFTPTTLTNG
Site 14T74RTSSFTPTTLTNGTS
Site 15T75TSSFTPTTLTNGTSH
Site 16T77SFTPTTLTNGTSHSP
Site 17S81TTLTNGTSHSPTALN
Site 18S83LTNGTSHSPTALNGA
Site 19T85NGTSHSPTALNGAPS
Site 20S92TALNGAPSPPNGFSN
Site 21S98PSPPNGFSNGPSSSS
Site 22S102NGFSNGPSSSSSSSL
Site 23S103GFSNGPSSSSSSSLA
Site 24S104FSNGPSSSSSSSLAN
Site 25S105SNGPSSSSSSSLANQ
Site 26S106NGPSSSSSSSLANQQ
Site 27S107GPSSSSSSSLANQQL
Site 28S108PSSSSSSSLANQQLP
Site 29S124ACGARQLSKLKRFLT
Site 30T131SKLKRFLTTLQQFGN
Site 31T132KLKRFLTTLQQFGND
Site 32S141QQFGNDISPEIGERV
Site 33T161GLVNSTLTIEEFHSK
Site 34S222EQLLLDASTTSPVDS
Site 35T223QLLLDASTTSPVDSS
Site 36S225LLDASTTSPVDSSEL
Site 37S229STTSPVDSSELLLDV
Site 38T244NENGKRRTPDRTKEN
Site 39T248KRRTPDRTKENGFDR
Site 40S260FDREPLHSEHPSKRP
Site 41S264PLHSEHPSKRPCTIS
Site 42T269HPSKRPCTISPGQRY
Site 43S271SKRPCTISPGQRYSP
Site 44S277ISPGQRYSPNNGLSY
Site 45S283YSPNNGLSYQPNGLP
Site 46Y284SPNNGLSYQPNGLPH
Site 47T293PNGLPHPTPPPPQHY
Site 48Y315AHHYRDSYRHPSHRD
Site 49S319RDSYRHPSHRDLRDR
Site 50T346EMIDHRLTDREWAEE
Site 51S374MVEKTRRSLTVLRRC
Site 52T376EKTRRSLTVLRRCQE
Site 53Y391ADREELNYWIRRYSD
Site 54Y396LNYWIRRYSDAEDLK
Site 55S397NYWIRRYSDAEDLKK
Site 56S408DLKKGGGSSSSHSRQ
Site 57S409LKKGGGSSSSHSRQQ
Site 58S410KKGGGSSSSHSRQQS
Site 59S411KGGGSSSSHSRQQSP
Site 60S413GGSSSSHSRQQSPVN
Site 61S417PPAATPRSTTPGTPS
Site 62S438EFLHRPASGYVPEEI
Site 63Y440LHRPASGYVPEEIWK
Site 64S469TELQKAVSEAERKAH
Site 65T480RKAHDMITTERAKME
Site 66T481KAHDMITTERAKMER
Site 67T525CGRKASETCSGCNTA
Site 68S527RKASETCSGCNTARY
Site 69T563QAQQQGDTPAVSSSV
Site 70S567QGDTPAVSSSVTPNS
Site 71S569DTPAVSSSVTPNSGA
Site 72T571PAVSSSVTPNSGAGS
Site 73S574SSSVTPNSGAGSPMD
Site 74S578TPNSGAGSPMDTPPA
Site 75T582GAGSPMDTPPAATPR
Site 76T587MDTPPAATPRSTTPG
Site 77S590PPAATPRSTTPGTPS
Site 78T591PAATPRSTTPGTPST
Site 79T592AATPRSTTPGTPSTI
Site 80T595PRSTTPGTPSTIETT
Site 81T598TTPGTPSTIETTPR_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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