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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPAT
Full Name:
Amidophosphoribosyltransferase
Alias:
Glutamine phosphoribosylpyrophosphate amidotransferase
Type:
Mass (Da):
57381
Number AA:
517
UniProt ID:
Q06203
International Prot ID:
IPI00029534
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0000287
GO:0003824
GO:0004044
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006139
GO:0006144
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S53
E
S
A
G
I
V
T
S
D
G
S
S
V
P
T
Site 2
S56
G
I
V
T
S
D
G
S
S
V
P
T
F
K
S
Site 3
S57
I
V
T
S
D
G
S
S
V
P
T
F
K
S
H
Site 4
T60
S
D
G
S
S
V
P
T
F
K
S
H
K
G
M
Site 5
S63
S
S
V
P
T
F
K
S
H
K
G
M
G
L
V
Site 6
Y83
E
D
N
L
K
K
L
Y
V
S
N
L
G
I
G
Site 7
Y94
L
G
I
G
H
T
R
Y
A
T
T
G
K
C
E
Site 8
T96
I
G
H
T
R
Y
A
T
T
G
K
C
E
L
E
Site 9
S143
L
R
H
G
I
G
L
S
T
S
S
D
S
E
M
Site 10
T144
R
H
G
I
G
L
S
T
S
S
D
S
E
M
I
Site 11
S145
H
G
I
G
L
S
T
S
S
D
S
E
M
I
T
Site 12
S146
G
I
G
L
S
T
S
S
D
S
E
M
I
T
Q
Site 13
S148
G
L
S
T
S
S
D
S
E
M
I
T
Q
L
L
Site 14
T152
S
S
D
S
E
M
I
T
Q
L
L
A
Y
T
P
Site 15
Y157
M
I
T
Q
L
L
A
Y
T
P
P
Q
E
Q
D
Site 16
T158
I
T
Q
L
L
A
Y
T
P
P
Q
E
Q
D
D
Site 17
T166
P
P
Q
E
Q
D
D
T
P
D
W
V
A
R
I
Site 18
Y195
I
M
H
R
D
V
I
Y
A
V
R
D
P
Y
G
Site 19
Y201
I
Y
A
V
R
D
P
Y
G
N
R
P
L
C
I
Site 20
S215
I
G
R
L
I
P
V
S
D
I
N
D
K
E
K
Site 21
S225
N
D
K
E
K
K
T
S
E
T
E
G
W
V
V
Site 22
S233
E
T
E
G
W
V
V
S
S
E
S
C
S
F
L
Site 23
S234
T
E
G
W
V
V
S
S
E
S
C
S
F
L
S
Site 24
S241
S
E
S
C
S
F
L
S
I
G
A
R
Y
Y
R
Site 25
Y247
L
S
I
G
A
R
Y
Y
R
E
V
L
P
G
E
Site 26
T265
I
S
R
H
N
V
Q
T
L
D
I
I
S
R
S
Site 27
S292
V
Y
F
A
R
P
D
S
M
F
E
D
Q
M
V
Site 28
Y300
M
F
E
D
Q
M
V
Y
T
V
R
Y
R
C
G
Site 29
Y352
E
V
L
C
K
N
R
Y
V
G
R
T
F
I
Q
Site 30
T356
K
N
R
Y
V
G
R
T
F
I
Q
P
N
M
R
Site 31
S377
A
K
K
F
G
V
L
S
D
N
F
K
G
K
R
Site 32
S419
E
V
H
I
R
V
A
S
P
P
I
K
Y
P
C
Site 33
T504
F
E
K
S
G
H
C
T
A
C
L
T
G
K
Y
Site 34
Y511
T
A
C
L
T
G
K
Y
P
V
E
L
E
W
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation