PhosphoNET

           
Protein Info 
   
Short Name:  EGR4
Full Name:  Early growth response protein 4
Alias:  AT133
Type: 
Mass (Da):  50799
Number AA:  486
UniProt ID:  Q05215
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T41ARDAPAATGYPGAGD
Site 2Y43DAPAATGYPGAGDFL
Site 3T75FLEGPAPTPPPGLSY
Site 4S81PTPPPGLSYSGSFFI
Site 5S83PPPGLSYSGSFFIQA
Site 6S122PGPEAAASRSPLDAP
Site 7S124PEAAASRSPLDAPFP
Site 8S134DAPFPAGSDALLPGP
Site 9Y145LPGPPDLYSPDLGAA
Site 10S146PGPPDLYSPDLGAAP
Site 11S162PEAFWEASPCAGAPS
Site 12S169SPCAGAPSQCLYEPQ
Site 13Y173GAPSQCLYEPQLSPP
Site 14S178CLYEPQLSPPDVKPG
Site 15S221GAPGNCGSQGDYQAA
Site 16Y225NCGSQGDYQAAPEAR
Site 17Y261AVPANRLYPSGAYDA
Site 18T288EGLPGLLTPPSGEGG
Site 19S291PGLLTPPSGEGGSSG
Site 20S297PSGEGGSSGDGGEFL
Site 21S306DGGEFLASTQPQLSP
Site 22T307GGEFLASTQPQLSPL
Site 23S312ASTQPQLSPLGLRSA
Site 24T349PVPPPPPTPFPQAKA
Site 25S367GRRGGKCSTRCFCPR
Site 26T368RRGGKCSTRCFCPRP
Site 27S390PVESCVRSFARSDEL
Site 28S394CVRSFARSDELNRHL
Site 29T405NRHLRIHTGHKPFQC
Site 30S420RICLRNFSRSDHLTT
Site 31S422CLRNFSRSDHLTTHV
Site 32T426FSRSDHLTTHVRTHT
Site 33T427SRSDHLTTHVRTHTG
Site 34T431HLTTHVRTHTGEKPF
Site 35T433TTHVRTHTGEKPFAC
Site 36S450CGRRFARSDEKKRHS
Site 37S457SDEKKRHSKVHLKQK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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