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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OCA2
Full Name:
P protein
Alias:
Melanocyte-specific transporter protein, Pink-eyed dilution protein homologue
Type:
Membrane protein, integral, Transporter
Mass (Da):
92850
Number AA:
838
UniProt ID:
Q04671
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005302
GO:0015105
GO:0015137
PhosphoSite+
KinaseNET
Biological Process:
GO:0015746
GO:0006726
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
E
G
R
D
G
R
R
Y
P
G
A
P
A
V
E
Site 2
S48
G
A
G
G
A
D
P
S
H
S
C
P
R
G
A
Site 3
S50
G
G
A
D
P
S
H
S
C
P
R
G
A
A
G
Site 4
S60
R
G
A
A
G
Q
S
S
W
A
P
A
G
Q
E
Site 5
S70
P
A
G
Q
E
F
A
S
F
L
T
K
G
R
S
Site 6
T73
Q
E
F
A
S
F
L
T
K
G
R
S
H
S
S
Site 7
S77
S
F
L
T
K
G
R
S
H
S
S
L
P
Q
M
Site 8
S79
L
T
K
G
R
S
H
S
S
L
P
Q
M
S
S
Site 9
S80
T
K
G
R
S
H
S
S
L
P
Q
M
S
S
S
Site 10
S85
H
S
S
L
P
Q
M
S
S
S
R
S
K
D
S
Site 11
S86
S
S
L
P
Q
M
S
S
S
R
S
K
D
S
C
Site 12
S87
S
L
P
Q
M
S
S
S
R
S
K
D
S
C
F
Site 13
S89
P
Q
M
S
S
S
R
S
K
D
S
C
F
T
E
Site 14
S92
S
S
S
R
S
K
D
S
C
F
T
E
N
T
P
Site 15
T98
D
S
C
F
T
E
N
T
P
L
L
R
N
S
L
Site 16
S104
N
T
P
L
L
R
N
S
L
Q
E
K
G
S
R
Site 17
S110
N
S
L
Q
E
K
G
S
R
C
I
P
V
Y
H
Site 18
S126
E
F
I
T
A
E
E
S
W
E
D
S
S
A
D
Site 19
S130
A
E
E
S
W
E
D
S
S
A
D
W
E
R
R
Site 20
S131
E
E
S
W
E
D
S
S
A
D
W
E
R
R
Y
Site 21
Y138
S
A
D
W
E
R
R
Y
L
L
S
R
E
V
S
Site 22
S141
W
E
R
R
Y
L
L
S
R
E
V
S
G
L
S
Site 23
S145
Y
L
L
S
R
E
V
S
G
L
S
A
S
A
S
Site 24
S148
S
R
E
V
S
G
L
S
A
S
A
S
S
E
K
Site 25
S150
E
V
S
G
L
S
A
S
A
S
S
E
K
G
D
Site 26
S152
S
G
L
S
A
S
A
S
S
E
K
G
D
L
L
Site 27
S161
E
K
G
D
L
L
D
S
P
H
I
R
L
R
L
Site 28
S169
P
H
I
R
L
R
L
S
K
L
R
R
C
V
Q
Site 29
Y215
A
L
S
P
L
E
N
Y
S
V
N
L
S
S
H
Site 30
S216
L
S
P
L
E
N
Y
S
V
N
L
S
S
H
V
Site 31
S220
E
N
Y
S
V
N
L
S
S
H
V
D
S
T
L
Site 32
S221
N
Y
S
V
N
L
S
S
H
V
D
S
T
L
L
Site 33
S262
T
Q
A
D
A
L
G
S
R
W
R
R
P
Q
Q
Site 34
Y277
V
T
H
N
W
T
V
Y
L
N
P
R
R
S
E
Site 35
S283
V
Y
L
N
P
R
R
S
E
H
S
V
M
S
R
Site 36
S286
N
P
R
R
S
E
H
S
V
M
S
R
T
F
E
Site 37
T291
E
H
S
V
M
S
R
T
F
E
V
L
T
R
E
Site 38
T296
S
R
T
F
E
V
L
T
R
E
T
V
S
I
S
Site 39
S303
T
R
E
T
V
S
I
S
I
R
A
S
L
Q
Q
Site 40
Y322
P
L
L
M
A
H
Q
Y
L
R
G
S
V
E
T
Site 41
S326
A
H
Q
Y
L
R
G
S
V
E
T
Q
V
T
I
Site 42
T377
I
G
D
R
P
S
L
T
H
V
V
E
W
I
D
Site 43
Y409
S
E
T
G
F
F
D
Y
C
A
V
K
A
Y
R
Site 44
S418
A
V
K
A
Y
R
L
S
R
G
R
V
W
A
M
Site 45
Y531
F
P
L
L
R
L
L
Y
W
N
R
K
L
Y
N
Site 46
Y537
L
Y
W
N
R
K
L
Y
N
K
E
P
S
E
I
Site 47
T557
E
I
H
V
W
R
L
T
A
Q
R
I
S
P
A
Site 48
S562
R
L
T
A
Q
R
I
S
P
A
S
R
E
E
T
Site 49
S565
A
Q
R
I
S
P
A
S
R
E
E
T
A
V
R
Site 50
T569
S
P
A
S
R
E
E
T
A
V
R
R
L
L
L
Site 51
T592
L
L
A
R
R
L
H
T
F
H
R
Q
I
S
Q
Site 52
S618
L
Q
K
K
H
R
I
S
D
G
I
L
L
A
K
Site 53
Y802
G
I
A
E
Q
H
G
Y
G
F
S
F
M
E
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation