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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EVX2
Full Name:
Homeobox even-skipped homolog protein 2
Alias:
Eve, even-skipped homeo box 2; Even-skipped homeo box-2; EVX-2
Type:
Mass (Da):
47800
Number AA:
476
UniProt ID:
Q03828
International Prot ID:
IPI00012495
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
L
M
E
R
G
L
H
S
P
T
A
G
K
R
F
Site 2
S26
P
T
A
G
K
R
F
S
N
L
S
N
S
A
G
Site 3
S29
G
K
R
F
S
N
L
S
N
S
A
G
N
A
V
Site 4
S31
R
F
S
N
L
S
N
S
A
G
N
A
V
L
E
Site 5
S43
V
L
E
A
L
E
N
S
Q
H
P
A
R
L
S
Site 6
S50
S
Q
H
P
A
R
L
S
P
R
L
P
S
A
P
Site 7
S55
R
L
S
P
R
L
P
S
A
P
L
H
S
A
L
Site 8
T75
K
G
K
F
E
I
D
T
L
F
N
L
Q
H
T
Site 9
T82
T
L
F
N
L
Q
H
T
G
S
E
S
T
V
S
Site 10
S84
F
N
L
Q
H
T
G
S
E
S
T
V
S
S
E
Site 11
S86
L
Q
H
T
G
S
E
S
T
V
S
S
E
I
S
Site 12
T87
Q
H
T
G
S
E
S
T
V
S
S
E
I
S
S
Site 13
S89
T
G
S
E
S
T
V
S
S
E
I
S
S
A
A
Site 14
S90
G
S
E
S
T
V
S
S
E
I
S
S
A
A
E
Site 15
S93
S
T
V
S
S
E
I
S
S
A
A
E
S
R
K
Site 16
S94
T
V
S
S
E
I
S
S
A
A
E
S
R
K
K
Site 17
S98
E
I
S
S
A
A
E
S
R
K
K
P
G
H
Y
Site 18
S106
R
K
K
P
G
H
Y
S
E
A
A
A
E
A
D
Site 19
S115
A
A
A
E
A
D
M
S
S
D
V
E
V
G
C
Site 20
S116
A
A
E
A
D
M
S
S
D
V
E
V
G
C
S
Site 21
S123
S
D
V
E
V
G
C
S
A
L
R
S
P
G
G
Site 22
S127
V
G
C
S
A
L
R
S
P
G
G
L
G
A
A
Site 23
Y144
K
E
N
N
G
K
G
Y
A
E
S
G
S
A
A
Site 24
S147
N
G
K
G
Y
A
E
S
G
S
A
A
G
T
T
Site 25
S149
K
G
Y
A
E
S
G
S
A
A
G
T
T
T
S
Site 26
T153
E
S
G
S
A
A
G
T
T
T
S
A
S
G
S
Site 27
T154
S
G
S
A
A
G
T
T
T
S
A
S
G
S
G
Site 28
S156
S
A
A
G
T
T
T
S
A
S
G
S
G
L
G
Site 29
S160
T
T
T
S
A
S
G
S
G
L
G
S
L
H
G
Site 30
S164
A
S
G
S
G
L
G
S
L
H
G
G
S
G
G
Site 31
S169
L
G
S
L
H
G
G
S
G
G
S
G
G
S
A
Site 32
S175
G
S
G
G
S
G
G
S
A
A
L
G
G
S
G
Site 33
S181
G
S
A
A
L
G
G
S
G
S
G
A
D
Q
V
Site 34
S183
A
A
L
G
G
S
G
S
G
A
D
Q
V
R
R
Site 35
Y191
G
A
D
Q
V
R
R
Y
R
T
A
F
T
R
E
Site 36
T193
D
Q
V
R
R
Y
R
T
A
F
T
R
E
Q
I
Site 37
Y208
A
R
L
E
K
E
F
Y
R
E
N
Y
V
S
R
Site 38
Y212
K
E
F
Y
R
E
N
Y
V
S
R
P
R
R
C
Site 39
S214
F
Y
R
E
N
Y
V
S
R
P
R
R
C
E
L
Site 40
Y263
A
D
P
S
F
Y
T
Y
M
M
T
H
A
A
A
Site 41
S273
T
H
A
A
A
T
G
S
L
P
Y
P
F
H
S
Site 42
Y276
A
A
T
G
S
L
P
Y
P
F
H
S
H
V
P
Site 43
Y286
H
S
H
V
P
L
H
Y
Y
P
H
V
G
V
T
Site 44
Y287
S
H
V
P
L
H
Y
Y
P
H
V
G
V
T
A
Site 45
T314
A
A
S
S
P
F
A
T
S
I
R
P
L
D
T
Site 46
S315
A
S
S
P
F
A
T
S
I
R
P
L
D
T
F
Site 47
T321
T
S
I
R
P
L
D
T
F
R
A
L
S
H
P
Site 48
S326
L
D
T
F
R
A
L
S
H
P
Y
S
R
P
E
Site 49
Y329
F
R
A
L
S
H
P
Y
S
R
P
E
L
L
C
Site 50
S330
R
A
L
S
H
P
Y
S
R
P
E
L
L
C
S
Site 51
S337
S
R
P
E
L
L
C
S
F
R
H
P
G
L
Y
Site 52
Y344
S
F
R
H
P
G
L
Y
Q
A
P
A
A
A
A
Site 53
S384
G
A
P
P
S
G
G
S
A
P
C
S
C
L
S
Site 54
S388
S
G
G
S
A
P
C
S
C
L
S
C
H
S
S
Site 55
S391
S
A
P
C
S
C
L
S
C
H
S
S
Q
S
A
Site 56
S446
C
S
A
A
A
P
R
S
E
S
G
F
L
P
Y
Site 57
S448
A
A
A
P
R
S
E
S
G
F
L
P
Y
S
A
Site 58
T461
S
A
A
V
L
S
K
T
A
V
S
P
P
D
Q
Site 59
S464
V
L
S
K
T
A
V
S
P
P
D
Q
R
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation