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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAP2
Full Name:
Antigen peptide transporter 2
Alias:
ATP-binding cassette sub-family B member 3;Peptide supply factor 2;Peptide transporter PSF2;Peptide transporter TAP2;Peptide transporter involved in antigen processing 2;Really interesting new gene 11 protein
Type:
Mass (Da):
75664
Number AA:
686
UniProt ID:
Q03519
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S120
W
S
L
W
A
V
L
S
P
P
G
A
Q
E
K
Site 2
Y216
C
R
G
G
C
F
T
Y
T
M
S
R
I
N
L
Site 3
T217
R
G
G
C
F
T
Y
T
M
S
R
I
N
L
R
Site 4
S231
R
I
R
E
Q
L
F
S
S
L
L
R
Q
D
L
Site 5
S232
I
R
E
Q
L
F
S
S
L
L
R
Q
D
L
G
Site 6
T246
G
F
F
Q
E
T
K
T
G
E
L
N
S
R
L
Site 7
S251
T
K
T
G
E
L
N
S
R
L
S
S
D
T
T
Site 8
S254
G
E
L
N
S
R
L
S
S
D
T
T
L
M
S
Site 9
S255
E
L
N
S
R
L
S
S
D
T
T
L
M
S
N
Site 10
T257
N
S
R
L
S
S
D
T
T
L
M
S
N
W
L
Site 11
T258
S
R
L
S
S
D
T
T
L
M
S
N
W
L
P
Site 12
S261
S
S
D
T
T
L
M
S
N
W
L
P
L
N
A
Site 13
S274
N
A
N
V
L
L
R
S
L
V
K
V
V
G
L
Site 14
T341
E
A
V
G
G
L
Q
T
V
R
S
F
G
A
E
Site 15
S344
G
G
L
Q
T
V
R
S
F
G
A
E
E
H
E
Site 16
Y355
E
E
H
E
V
C
R
Y
K
E
A
L
E
Q
C
Site 17
Y366
L
E
Q
C
R
Q
L
Y
W
R
R
D
L
E
R
Site 18
T405
Q
M
Q
D
G
E
L
T
Q
G
S
L
L
S
F
Site 19
S418
S
F
M
I
Y
Q
E
S
V
G
S
Y
V
Q
T
Site 20
S435
Y
I
Y
G
D
M
L
S
N
V
G
A
A
E
K
Site 21
Y446
A
A
E
K
V
F
S
Y
M
D
R
Q
P
N
L
Site 22
S455
D
R
Q
P
N
L
P
S
P
G
T
L
A
P
T
Site 23
T458
P
N
L
P
S
P
G
T
L
A
P
T
T
L
Q
Site 24
S474
V
V
K
F
Q
D
V
S
F
A
Y
P
N
R
P
Site 25
Y477
F
Q
D
V
S
F
A
Y
P
N
R
P
D
R
P
Site 26
T490
R
P
V
L
K
G
L
T
F
T
L
R
P
G
E
Site 27
T499
T
L
R
P
G
E
V
T
A
L
V
G
P
N
G
Site 28
S510
G
P
N
G
S
G
K
S
T
V
A
A
L
L
Q
Site 29
T511
P
N
G
S
G
K
S
T
V
A
A
L
L
Q
N
Site 30
S535
L
L
D
E
K
P
I
S
Q
Y
E
H
C
Y
L
Site 31
Y537
D
E
K
P
I
S
Q
Y
E
H
C
Y
L
H
S
Site 32
Y541
I
S
Q
Y
E
H
C
Y
L
H
S
Q
V
V
S
Site 33
S559
E
P
V
L
F
S
G
S
V
R
N
N
I
A
Y
Site 34
Y566
S
V
R
N
N
I
A
Y
G
L
Q
S
C
E
D
Site 35
Y597
Q
E
M
E
H
G
I
Y
T
D
V
G
E
K
G
Site 36
S650
Q
A
L
Q
D
W
N
S
R
G
D
R
T
V
L
Site 37
T655
W
N
S
R
G
D
R
T
V
L
V
I
A
H
R
Site 38
T665
V
I
A
H
R
L
Q
T
V
Q
R
A
H
Q
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation