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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAP1
Full Name:
Antigen peptide transporter 1
Alias:
ATP-binding cassette sub-family B member 2;Peptide supply factor 1;Peptide transporter PSF1;Peptide transporter TAP1;Peptide transporter involved in antigen processing 1;Really interesting new gene 4 protein
Type:
Mass (Da):
87218
Number AA:
808
UniProt ID:
Q03518
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
D
F
P
R
A
P
P
S
F
P
P
P
A
A
S
Site 2
S29
S
F
P
P
P
A
A
S
R
G
G
L
G
G
T
Site 3
T36
S
R
G
G
L
G
G
T
R
S
F
R
P
H
R
Site 4
S38
G
G
L
G
G
T
R
S
F
R
P
H
R
G
A
Site 5
S47
R
P
H
R
G
A
E
S
P
R
P
G
R
D
R
Site 6
S63
G
V
R
V
P
M
A
S
S
R
C
P
A
P
R
Site 7
S64
V
R
V
P
M
A
S
S
R
C
P
A
P
R
G
Site 8
T139
A
C
G
V
L
R
A
T
V
G
S
K
S
E
N
Site 9
S142
V
L
R
A
T
V
G
S
K
S
E
N
A
G
A
Site 10
S144
R
A
T
V
G
S
K
S
E
N
A
G
A
Q
G
Site 11
S184
I
S
W
G
A
P
G
S
A
D
S
T
R
L
L
Site 12
S187
G
A
P
G
S
A
D
S
T
R
L
L
H
W
G
Site 13
T188
A
P
G
S
A
D
S
T
R
L
L
H
W
G
S
Site 14
S229
V
P
G
G
Q
G
G
S
G
N
P
V
R
R
L
Site 15
S242
R
L
L
G
C
L
G
S
E
T
R
R
L
S
L
Site 16
T283
L
Q
D
G
S
A
D
T
F
T
R
N
L
T
L
Site 17
T285
D
G
S
A
D
T
F
T
R
N
L
T
L
M
S
Site 18
Y309
E
F
V
G
D
G
I
Y
N
N
T
M
G
H
V
Site 19
T333
G
A
V
L
R
Q
E
T
E
F
F
Q
Q
N
Q
Site 20
T349
G
N
I
M
S
R
V
T
E
D
T
S
T
L
S
Site 21
T352
M
S
R
V
T
E
D
T
S
T
L
S
D
S
L
Site 22
S353
S
R
V
T
E
D
T
S
T
L
S
D
S
L
S
Site 23
T354
R
V
T
E
D
T
S
T
L
S
D
S
L
S
E
Site 24
S356
T
E
D
T
S
T
L
S
D
S
L
S
E
N
L
Site 25
S358
D
T
S
T
L
S
D
S
L
S
E
N
L
S
L
Site 26
Y369
N
L
S
L
F
L
W
Y
L
V
R
G
L
C
L
Site 27
T388
L
W
G
S
V
S
L
T
M
V
T
L
I
T
L
Site 28
S419
L
E
V
Q
V
R
E
S
L
A
K
S
S
Q
V
Site 29
S423
V
R
E
S
L
A
K
S
S
Q
V
A
I
E
A
Site 30
S424
R
E
S
L
A
K
S
S
Q
V
A
I
E
A
L
Site 31
T436
E
A
L
S
A
M
P
T
V
R
S
F
A
N
E
Site 32
S439
S
A
M
P
T
V
R
S
F
A
N
E
E
G
E
Site 33
T459
E
K
L
Q
E
I
K
T
L
N
Q
K
E
A
V
Site 34
Y468
N
Q
K
E
A
V
A
Y
A
V
N
S
W
T
T
Site 35
Y541
S
S
E
K
I
F
E
Y
L
D
R
T
P
R
C
Site 36
T545
I
F
E
Y
L
D
R
T
P
R
C
P
P
S
G
Site 37
S551
R
T
P
R
C
P
P
S
G
L
L
T
P
L
H
Site 38
S569
L
V
Q
F
Q
D
V
S
F
A
Y
P
N
R
P
Site 39
Y572
F
Q
D
V
S
F
A
Y
P
N
R
P
D
V
L
Site 40
T594
T
L
R
P
G
E
V
T
A
L
V
G
P
N
G
Site 41
S605
G
P
N
G
S
G
K
S
T
V
A
A
L
L
Q
Site 42
T606
P
N
G
S
G
K
S
T
V
A
A
L
L
Q
N
Site 43
Y615
A
A
L
L
Q
N
L
Y
Q
P
T
G
G
Q
L
Site 44
Y632
D
G
K
P
L
P
Q
Y
E
H
R
Y
L
H
R
Site 45
Y636
L
P
Q
Y
E
H
R
Y
L
H
R
Q
V
A
A
Site 46
Y661
S
L
Q
E
N
I
A
Y
G
L
T
Q
K
P
T
Site 47
T664
E
N
I
A
Y
G
L
T
Q
K
P
T
M
E
E
Site 48
S686
S
G
A
H
S
F
I
S
G
L
P
Q
G
Y
D
Site 49
T694
G
L
P
Q
G
Y
D
T
E
V
D
E
A
G
S
Site 50
S701
T
E
V
D
E
A
G
S
Q
L
S
G
G
Q
R
Site 51
S731
L
I
L
D
D
A
T
S
A
L
D
A
N
S
Q
Site 52
S737
T
S
A
L
D
A
N
S
Q
L
Q
V
E
Q
L
Site 53
Y746
L
Q
V
E
Q
L
L
Y
E
S
P
E
R
Y
S
Site 54
S748
V
E
Q
L
L
Y
E
S
P
E
R
Y
S
R
S
Site 55
Y752
L
Y
E
S
P
E
R
Y
S
R
S
V
L
L
I
Site 56
S753
Y
E
S
P
E
R
Y
S
R
S
V
L
L
I
T
Site 57
S755
S
P
E
R
Y
S
R
S
V
L
L
I
T
Q
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation