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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GSTM4
Full Name:
Glutathione S-transferase Mu 4
Alias:
EC 2.5.1.18; Glutathione S-alkyltransferase M4; Glutathione S-aralkyltransferase M4; Glutathione S-aryltransferase M4; Glutathione S-transferase M4; Glutathione S-transferase M4, isoform 1; Glutathione S-transferase, Mu-4; GST class-mu 4; GSTM4-4; GTM4; GTS-Mu2; S-(hydroxyalkyl)glutathione lyase M4
Type:
Xenobiotics - metabolism by cytochrome P450, Transferase, Xenobiotics - drug metabolism - cytochrome P450, Other Amino Acids - glutathione metabolism
Mass (Da):
25561
Number AA:
218
UniProt ID:
Q03013
International Prot ID:
IPI00008770
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0004364
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y23
A
I
R
L
L
L
E
Y
T
D
S
S
Y
E
E
Site 2
T24
I
R
L
L
L
E
Y
T
D
S
S
Y
E
E
K
Site 3
S26
L
L
L
E
Y
T
D
S
S
Y
E
E
K
K
Y
Site 4
S27
L
L
E
Y
T
D
S
S
Y
E
E
K
K
Y
T
Site 5
Y28
L
E
Y
T
D
S
S
Y
E
E
K
K
Y
T
M
Site 6
Y33
S
S
Y
E
E
K
K
Y
T
M
G
D
A
P
D
Site 7
T34
S
Y
E
E
K
K
Y
T
M
G
D
A
P
D
Y
Site 8
Y41
T
M
G
D
A
P
D
Y
D
R
S
Q
W
L
N
Site 9
Y62
L
D
F
P
N
L
P
Y
L
I
D
G
A
H
K
Site 10
T71
I
D
G
A
H
K
I
T
Q
S
N
A
I
L
C
Site 11
S73
G
A
H
K
I
T
Q
S
N
A
I
L
C
Y
I
Site 12
Y79
Q
S
N
A
I
L
C
Y
I
A
R
K
H
N
L
Site 13
Y116
N
Q
L
A
R
V
C
Y
S
P
D
F
E
K
L
Site 14
S117
Q
L
A
R
V
C
Y
S
P
D
F
E
K
L
K
Site 15
Y127
F
E
K
L
K
P
E
Y
L
E
E
L
P
T
M
Site 16
T133
E
Y
L
E
E
L
P
T
M
M
Q
H
F
S
Q
Site 17
S186
P
N
L
K
D
F
I
S
R
F
E
G
L
E
K
Site 18
Y197
G
L
E
K
I
S
A
Y
M
K
S
S
R
F
L
Site 19
S200
K
I
S
A
Y
M
K
S
S
R
F
L
P
K
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation