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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CREB5
Full Name:
Cyclic AMP-responsive element-binding protein 5
Alias:
CAMP response element binding protein 5; CAMP response element binding protein CRE-Bpa; CAMP response element-binding protein CRE-BPa; CAMP responsive element binding protein 5; CREBPA; CRE-BPa; H_GS165L15.1
Type:
Intracellular, Nucleus protein
Mass (Da):
56858
Number AA:
508
UniProt ID:
Q02930
International Prot ID:
IPI00027461
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006351
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y3
_
_
_
_
_
M
I
Y
E
E
S
K
M
N
L
Site 2
S16
N
L
E
Q
E
R
P
S
V
C
S
A
P
G
C
Site 3
S19
Q
E
R
P
S
V
C
S
A
P
G
C
S
Q
R
Site 4
S24
V
C
S
A
P
G
C
S
Q
R
F
P
T
E
D
Site 5
T29
G
C
S
Q
R
F
P
T
E
D
H
L
M
I
H
Site 6
T51
L
K
F
P
S
I
K
T
D
N
M
L
S
D
Q
Site 7
S56
I
K
T
D
N
M
L
S
D
Q
T
P
T
P
T
Site 8
T59
D
N
M
L
S
D
Q
T
P
T
P
T
R
F
L
Site 9
T61
M
L
S
D
Q
T
P
T
P
T
R
F
L
K
N
Site 10
T63
S
D
Q
T
P
T
P
T
R
F
L
K
N
C
E
Site 11
S81
L
F
S
E
L
D
C
S
L
E
H
E
F
R
K
Site 12
S94
R
K
A
Q
E
E
E
S
S
K
R
N
I
S
M
Site 13
S95
K
A
Q
E
E
E
S
S
K
R
N
I
S
M
H
Site 14
S100
E
S
S
K
R
N
I
S
M
H
N
A
V
G
G
Site 15
T114
G
A
M
T
G
P
G
T
H
Q
L
S
S
A
R
Site 16
S118
G
P
G
T
H
Q
L
S
S
A
R
L
P
N
H
Site 17
S119
P
G
T
H
Q
L
S
S
A
R
L
P
N
H
D
Site 18
T127
A
R
L
P
N
H
D
T
N
V
V
I
Q
Q
A
Site 19
S137
V
I
Q
Q
A
M
P
S
P
Q
S
S
S
V
I
Site 20
S140
Q
A
M
P
S
P
Q
S
S
S
V
I
T
Q
A
Site 21
S141
A
M
P
S
P
Q
S
S
S
V
I
T
Q
A
P
Site 22
S142
M
P
S
P
Q
S
S
S
V
I
T
Q
A
P
S
Site 23
T145
P
Q
S
S
S
V
I
T
Q
A
P
S
T
N
R
Site 24
T150
V
I
T
Q
A
P
S
T
N
R
Q
I
G
P
V
Site 25
S163
P
V
P
G
S
L
S
S
L
L
H
L
H
N
R
Site 26
S178
Q
R
Q
P
M
P
A
S
M
P
G
T
L
P
N
Site 27
T182
M
P
A
S
M
P
G
T
L
P
N
P
T
M
P
Site 28
T187
P
G
T
L
P
N
P
T
M
P
G
S
S
A
V
Site 29
S203
M
P
M
E
R
Q
M
S
V
N
S
S
I
M
G
Site 30
S207
R
Q
M
S
V
N
S
S
I
M
G
M
Q
G
P
Site 31
S217
G
M
Q
G
P
N
L
S
N
P
C
A
S
P
Q
Site 32
S222
N
L
S
N
P
C
A
S
P
Q
V
Q
P
M
H
Site 33
T241
M
R
L
K
A
A
L
T
H
H
P
A
A
M
S
Site 34
S248
T
H
H
P
A
A
M
S
N
G
N
M
N
T
M
Site 35
T254
M
S
N
G
N
M
N
T
M
G
H
M
M
E
M
Site 36
S330
H
P
A
H
H
Q
T
S
P
H
P
P
L
H
T
Site 37
S344
T
G
N
Q
A
Q
V
S
P
A
T
Q
Q
M
Q
Site 38
T353
A
T
Q
Q
M
Q
P
T
Q
T
I
Q
P
P
Q
Site 39
T390
E
R
N
R
A
A
A
T
R
C
R
Q
K
R
K
Site 40
S402
K
R
K
V
W
V
M
S
L
E
K
K
A
E
E
Site 41
T413
K
A
E
E
L
T
Q
T
N
M
Q
L
Q
N
E
Site 42
T437
Q
L
K
Q
L
L
L
T
H
K
D
C
P
I
T
Site 43
Y453
M
Q
K
E
S
Q
G
Y
L
S
P
E
S
S
P
Site 44
S455
K
E
S
Q
G
Y
L
S
P
E
S
S
P
P
A
Site 45
S458
Q
G
Y
L
S
P
E
S
S
P
P
A
S
P
V
Site 46
S459
G
Y
L
S
P
E
S
S
P
P
A
S
P
V
P
Site 47
S463
P
E
S
S
P
P
A
S
P
V
P
A
C
S
Q
Site 48
S469
A
S
P
V
P
A
C
S
Q
Q
Q
V
I
Q
H
Site 49
T478
Q
Q
V
I
Q
H
N
T
I
T
T
S
S
S
V
Site 50
T480
V
I
Q
H
N
T
I
T
T
S
S
S
V
S
E
Site 51
S482
Q
H
N
T
I
T
T
S
S
S
V
S
E
V
V
Site 52
S484
N
T
I
T
T
S
S
S
V
S
E
V
V
G
S
Site 53
T493
S
E
V
V
G
S
S
T
L
S
Q
L
T
T
H
Site 54
S495
V
V
G
S
S
T
L
S
Q
L
T
T
H
R
T
Site 55
T499
S
T
L
S
Q
L
T
T
H
R
T
D
L
N
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation