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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUCB1
Full Name:
Nucleobindin-1
Alias:
CALNUC; NUC; nucleobindin 1; nucleobindin-1
Type:
DNA binding protein
Mass (Da):
53879
Number AA:
461
UniProt ID:
Q02818
International Prot ID:
IPI00295542
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005793
GO:0005794
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
P
P
S
G
P
R
G
T
L
L
Site 2
T39
G
A
P
N
K
E
E
T
P
A
T
E
S
P
D
Site 3
T42
N
K
E
E
T
P
A
T
E
S
P
D
T
G
L
Site 4
S44
E
E
T
P
A
T
E
S
P
D
T
G
L
Y
Y
Site 5
T47
P
A
T
E
S
P
D
T
G
L
Y
Y
H
R
Y
Site 6
Y50
E
S
P
D
T
G
L
Y
Y
H
R
Y
L
Q
E
Site 7
Y51
S
P
D
T
G
L
Y
Y
H
R
Y
L
Q
E
V
Site 8
Y54
T
G
L
Y
Y
H
R
Y
L
Q
E
V
I
D
V
Site 9
S82
A
N
A
E
D
I
K
S
G
K
L
S
R
E
L
Site 10
S86
D
I
K
S
G
K
L
S
R
E
L
D
F
V
S
Site 11
S93
S
R
E
L
D
F
V
S
H
H
V
R
T
K
L
Site 12
T148
L
D
P
Q
N
Q
H
T
F
E
A
R
D
L
E
Site 13
Y168
A
T
R
D
L
A
Q
Y
D
A
A
H
H
E
E
Site 14
Y179
H
H
E
E
F
K
R
Y
E
M
L
K
E
H
E
Site 15
Y190
K
E
H
E
R
R
R
Y
L
E
S
L
G
E
E
Site 16
S193
E
R
R
R
Y
L
E
S
L
G
E
E
Q
R
K
Site 17
S224
P
K
V
N
V
P
G
S
Q
A
Q
L
K
E
V
Site 18
S256
F
I
L
H
D
I
N
S
D
G
V
L
D
E
Q
Site 19
T270
Q
E
L
E
A
L
F
T
K
E
L
E
K
V
Y
Site 20
T313
T
N
Q
D
R
L
V
T
L
E
E
F
L
A
S
Site 21
S320
T
L
E
E
F
L
A
S
T
Q
R
K
E
F
G
Site 22
T321
L
E
E
F
L
A
S
T
Q
R
K
E
F
G
D
Site 23
T329
Q
R
K
E
F
G
D
T
G
E
G
W
E
T
V
Site 24
T335
D
T
G
E
G
W
E
T
V
E
M
H
P
A
Y
Site 25
Y342
T
V
E
M
H
P
A
Y
T
E
E
E
L
R
R
Site 26
S369
N
A
K
A
Q
R
L
S
Q
E
T
E
A
L
G
Site 27
T372
A
Q
R
L
S
Q
E
T
E
A
L
G
R
S
Q
Site 28
S378
E
T
E
A
L
G
R
S
Q
G
R
L
E
A
Q
Site 29
T426
Q
L
K
F
H
P
D
T
D
D
V
P
V
P
A
Site 30
S444
D
Q
K
E
V
D
T
S
E
K
K
L
L
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation