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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLOD1
Full Name:
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Alias:
Lysyl hydroxylase 1
Type:
Mass (Da):
83532
Number AA:
727
UniProt ID:
Q02809
International Prot ID:
IPI00027192
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005789
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0005488
GO:0005506
PhosphoSite+
KinaseNET
Biological Process:
GO:0001666
GO:0006082
GO:0006091
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T32
E
D
N
L
L
V
L
T
V
A
T
K
E
T
E
Site 2
Y53
R
S
A
Q
F
F
N
Y
K
I
Q
A
L
G
L
Site 3
S71
W
N
V
E
K
G
T
S
A
G
G
G
Q
K
V
Site 4
S108
S
Y
D
V
L
F
A
S
G
P
R
E
L
L
K
Site 5
S122
K
K
F
R
Q
A
R
S
Q
V
V
F
S
A
E
Site 6
Y133
F
S
A
E
E
L
I
Y
P
D
R
R
L
E
T
Site 7
T140
Y
P
D
R
R
L
E
T
K
Y
P
V
V
S
D
Site 8
Y142
D
R
R
L
E
T
K
Y
P
V
V
S
D
G
K
Site 9
S154
D
G
K
R
F
L
G
S
G
G
F
I
G
Y
A
Site 10
S165
I
G
Y
A
P
N
L
S
K
L
V
A
E
W
E
Site 11
S176
A
E
W
E
G
Q
D
S
D
S
D
Q
L
F
Y
Site 12
S178
W
E
G
Q
D
S
D
S
D
Q
L
F
Y
T
K
Site 13
Y183
S
D
S
D
Q
L
F
Y
T
K
I
F
L
D
P
Site 14
Y252
P
T
K
L
Q
L
N
Y
L
G
N
Y
I
P
R
Site 15
Y256
Q
L
N
Y
L
G
N
Y
I
P
R
F
W
T
F
Site 16
S276
V
C
D
E
G
L
R
S
L
K
G
I
G
D
E
Site 17
Y313
Q
R
L
L
R
L
H
Y
P
Q
K
H
M
R
L
Site 18
S342
E
F
L
A
Q
H
G
S
E
Y
Q
S
V
K
L
Site 19
Y344
L
A
Q
H
G
S
E
Y
Q
S
V
K
L
V
G
Site 20
S346
Q
H
G
S
E
Y
Q
S
V
K
L
V
G
P
E
Site 21
Y377
R
Q
D
R
S
C
T
Y
Y
F
S
V
D
A
D
Site 22
Y378
Q
D
R
S
C
T
Y
Y
F
S
V
D
A
D
V
Site 23
T409
N
V
I
A
P
L
M
T
R
H
G
R
L
W
S
Site 24
S423
S
N
F
W
G
A
L
S
A
D
G
Y
Y
A
R
Site 25
Y427
G
A
L
S
A
D
G
Y
Y
A
R
S
E
D
Y
Site 26
Y428
A
L
S
A
D
G
Y
Y
A
R
S
E
D
Y
V
Site 27
Y434
Y
Y
A
R
S
E
D
Y
V
D
I
V
Q
G
R
Site 28
S468
A
L
R
G
E
L
Q
S
S
D
L
F
H
H
S
Site 29
S469
L
R
G
E
L
Q
S
S
D
L
F
H
H
S
K
Site 30
S475
S
S
D
L
F
H
H
S
K
L
D
P
D
M
A
Site 31
S507
H
T
L
G
H
L
L
S
L
D
S
Y
R
T
T
Site 32
S510
G
H
L
L
S
L
D
S
Y
R
T
T
H
L
H
Site 33
Y511
H
L
L
S
L
D
S
Y
R
T
T
H
L
H
N
Site 34
T514
S
L
D
S
Y
R
T
T
H
L
H
N
D
L
W
Site 35
Y534
P
E
D
W
K
E
K
Y
I
H
Q
N
Y
T
K
Site 36
Y539
E
K
Y
I
H
Q
N
Y
T
K
A
L
A
G
K
Site 37
Y556
E
T
P
C
P
D
V
Y
W
F
P
I
F
T
E
Site 38
Y593
D
N
R
I
Q
G
G
Y
E
N
V
P
T
I
D
Site 39
Y619
W
H
K
F
L
L
E
Y
I
A
P
M
T
E
K
Site 40
T624
L
E
Y
I
A
P
M
T
E
K
L
Y
P
G
Y
Site 41
Y628
A
P
M
T
E
K
L
Y
P
G
Y
Y
T
R
A
Site 42
Y631
T
E
K
L
Y
P
G
Y
Y
T
R
A
Q
F
D
Site 43
Y632
E
K
L
Y
P
G
Y
Y
T
R
A
Q
F
D
L
Site 44
S652
Y
K
P
D
E
Q
P
S
L
M
P
H
H
D
A
Site 45
Y675
L
N
R
V
G
V
D
Y
E
G
G
G
C
R
F
Site 46
Y685
G
G
C
R
F
L
R
Y
N
C
S
I
R
A
P
Site 47
S688
R
F
L
R
Y
N
C
S
I
R
A
P
R
K
G
Site 48
T705
L
M
H
P
G
R
L
T
H
Y
H
E
G
L
P
Site 49
Y707
H
P
G
R
L
T
H
Y
H
E
G
L
P
T
T
Site 50
T713
H
Y
H
E
G
L
P
T
T
R
G
T
R
Y
I
Site 51
Y719
P
T
T
R
G
T
R
Y
I
A
V
S
F
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation