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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SP2
Full Name:
Transcription factor Sp2
Alias:
KIAA0048; Sp2 transcription factor; Transcription factor Sp2: Transcription factor Sp2: SP2 protein
Type:
Transcription factor
Mass (Da):
64900
Number AA:
613
UniProt ID:
Q02086
International Prot ID:
IPI00744064
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003702
GO:0042826
PhosphoSite+
KinaseNET
Biological Process:
GO:0006955
GO:0006357
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
S
D
P
Q
T
S
M
A
A
T
A
A
Site 2
T11
P
Q
T
S
M
A
A
T
A
A
V
S
P
S
D
Site 3
Y19
A
A
V
S
P
S
D
Y
L
Q
P
A
A
S
T
Site 4
S25
D
Y
L
Q
P
A
A
S
T
T
Q
D
S
Q
P
Site 5
T27
L
Q
P
A
A
S
T
T
Q
D
S
Q
P
S
P
Site 6
S30
A
A
S
T
T
Q
D
S
Q
P
S
P
L
A
L
Site 7
S33
T
T
Q
D
S
Q
P
S
P
L
A
L
L
A
A
Site 8
T55
P
A
V
E
A
A
V
T
P
P
A
P
P
Q
P
Site 9
T63
P
P
A
P
P
Q
P
T
P
R
K
L
V
P
I
Site 10
S78
K
P
A
P
L
P
L
S
P
G
K
N
S
F
G
Site 11
S83
P
L
S
P
G
K
N
S
F
G
I
L
S
S
K
Site 12
S99
N
I
L
Q
I
Q
G
S
Q
L
S
A
S
Y
P
Site 13
S102
Q
I
Q
G
S
Q
L
S
A
S
Y
P
G
G
Q
Site 14
S104
Q
G
S
Q
L
S
A
S
Y
P
G
G
Q
L
V
Site 15
Y105
G
S
Q
L
S
A
S
Y
P
G
G
Q
L
V
F
Site 16
Y132
R
S
N
A
N
I
Q
Y
Q
A
V
P
Q
I
Q
Site 17
S141
A
V
P
Q
I
Q
A
S
N
S
Q
T
I
Q
V
Site 18
S143
P
Q
I
Q
A
S
N
S
Q
T
I
Q
V
Q
P
Site 19
T145
I
Q
A
S
N
S
Q
T
I
Q
V
Q
P
N
L
Site 20
T168
G
T
N
Q
A
I
I
T
P
S
P
S
S
H
K
Site 21
S170
N
Q
A
I
I
T
P
S
P
S
S
H
K
P
V
Site 22
S172
A
I
I
T
P
S
P
S
S
H
K
P
V
P
I
Site 23
S173
I
I
T
P
S
P
S
S
H
K
P
V
P
I
K
Site 24
S187
K
P
A
P
I
Q
K
S
S
T
T
T
T
P
V
Site 25
T191
I
Q
K
S
S
T
T
T
T
P
V
Q
S
G
A
Site 26
T192
Q
K
S
S
T
T
T
T
P
V
Q
S
G
A
N
Site 27
T211
T
G
G
G
G
N
V
T
L
T
L
P
V
N
N
Site 28
T225
N
L
V
N
A
S
D
T
G
A
P
T
Q
L
L
Site 29
T233
G
A
P
T
Q
L
L
T
E
S
P
P
T
P
L
Site 30
S235
P
T
Q
L
L
T
E
S
P
P
T
P
L
S
K
Site 31
T238
L
L
T
E
S
P
P
T
P
L
S
K
T
N
K
Site 32
S241
E
S
P
P
T
P
L
S
K
T
N
K
K
A
R
Site 33
S251
N
K
K
A
R
K
K
S
L
P
A
S
Q
P
P
Site 34
S255
R
K
K
S
L
P
A
S
Q
P
P
V
A
V
A
Site 35
S289
N
N
L
L
I
V
Q
S
P
G
G
G
Q
P
A
Site 36
T333
A
A
S
A
T
L
P
T
V
P
Q
K
P
S
Q
Site 37
S339
P
T
V
P
Q
K
P
S
Q
N
F
Q
I
Q
A
Site 38
T350
Q
I
Q
A
A
E
P
T
P
T
Q
V
Y
I
R
Site 39
T352
Q
A
A
E
P
T
P
T
Q
V
Y
I
R
T
P
Site 40
Y355
E
P
T
P
T
Q
V
Y
I
R
T
P
S
G
E
Site 41
T358
P
T
Q
V
Y
I
R
T
P
S
G
E
V
Q
T
Site 42
S360
Q
V
Y
I
R
T
P
S
G
E
V
Q
T
V
L
Site 43
T375
V
Q
D
S
P
P
A
T
A
A
A
T
S
N
T
Site 44
T382
T
A
A
A
T
S
N
T
T
C
S
S
P
A
S
Site 45
S385
A
T
S
N
T
T
C
S
S
P
A
S
R
A
P
Site 46
S386
T
S
N
T
T
C
S
S
P
A
S
R
A
P
H
Site 47
S389
T
T
C
S
S
P
A
S
R
A
P
H
L
S
G
Site 48
S395
A
S
R
A
P
H
L
S
G
T
S
K
K
H
S
Site 49
S402
S
G
T
S
K
K
H
S
A
A
I
L
R
K
E
Site 50
T454
Q
G
V
P
V
T
I
T
N
T
G
G
Q
Q
Q
Site 51
T463
T
G
G
Q
Q
Q
L
T
V
Q
N
V
S
G
N
Site 52
T473
N
V
S
G
N
N
L
T
I
S
G
L
S
P
T
Site 53
S475
S
G
N
N
L
T
I
S
G
L
S
P
T
Q
I
Site 54
S478
N
L
T
I
S
G
L
S
P
T
Q
I
Q
L
Q
Site 55
T535
H
I
P
D
C
G
K
T
F
R
K
T
S
L
L
Site 56
T539
C
G
K
T
F
R
K
T
S
L
L
R
A
H
V
Site 57
S540
G
K
T
F
R
K
T
S
L
L
R
A
H
V
R
Site 58
T550
R
A
H
V
R
L
H
T
G
E
R
P
F
V
C
Site 59
T567
F
F
C
G
K
R
F
T
R
S
D
E
L
Q
R
Site 60
S569
C
G
K
R
F
T
R
S
D
E
L
Q
R
H
A
Site 61
T580
Q
R
H
A
R
T
H
T
G
D
K
R
F
E
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation