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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDR2
Full Name:
Cerebellar degeneration-related protein 2
Alias:
CDR62; Major Yo paraneoplastic antigen; Paraneoplastic cerebellar degeneration-associated antigen; PCD17; Yo
Type:
Mass (Da):
51855
Number AA:
454
UniProt ID:
Q01850
International Prot ID:
IPI00009862
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
M
K
E
D
E
P
W
Y
D
H
Q
D
L
Q
Q
Site 2
T37
L
A
A
E
L
G
K
T
L
L
D
R
N
T
E
Site 3
T43
K
T
L
L
D
R
N
T
E
L
E
D
S
V
Q
Site 4
S48
R
N
T
E
L
E
D
S
V
Q
Q
M
Y
T
T
Site 5
Y53
E
D
S
V
Q
Q
M
Y
T
T
N
Q
E
Q
L
Site 6
Y65
E
Q
L
Q
E
I
E
Y
L
T
K
Q
V
E
L
Site 7
T90
V
Y
E
Q
L
D
V
T
A
R
E
L
E
E
T
Site 8
T97
T
A
R
E
L
E
E
T
N
Q
K
L
V
A
D
Site 9
S114
A
S
Q
Q
K
I
L
S
L
T
E
T
I
E
C
Site 10
T124
E
T
I
E
C
L
Q
T
N
I
D
H
L
Q
S
Site 11
S131
T
N
I
D
H
L
Q
S
Q
V
E
E
L
K
S
Site 12
S138
S
Q
V
E
E
L
K
S
S
G
Q
G
R
R
S
Site 13
S139
Q
V
E
E
L
K
S
S
G
Q
G
R
R
S
P
Site 14
S145
S
S
G
Q
G
R
R
S
P
G
K
C
D
Q
E
Site 15
S157
D
Q
E
K
P
A
P
S
F
A
C
L
K
E
L
Site 16
Y173
D
L
R
Q
H
F
V
Y
D
H
V
F
A
E
K
Site 17
S183
V
F
A
E
K
I
T
S
L
Q
G
Q
P
S
P
Site 18
S189
T
S
L
Q
G
Q
P
S
P
D
E
E
E
N
E
Site 19
T201
E
N
E
H
L
K
K
T
V
T
M
L
Q
A
Q
Site 20
S210
T
M
L
Q
A
Q
L
S
L
E
R
Q
K
R
V
Site 21
T218
L
E
R
Q
K
R
V
T
M
E
E
E
Y
G
L
Site 22
Y243
Q
L
G
A
T
G
A
Y
R
A
R
A
L
E
L
Site 23
S278
V
E
K
L
V
P
D
S
L
Y
V
P
F
K
E
Site 24
Y280
K
L
V
P
D
S
L
Y
V
P
F
K
E
P
S
Site 25
S287
Y
V
P
F
K
E
P
S
Q
S
L
L
E
E
M
Site 26
S289
P
F
K
E
P
S
Q
S
L
L
E
E
M
F
L
Site 27
T297
L
L
E
E
M
F
L
T
V
P
E
S
H
R
K
Site 28
S301
M
F
L
T
V
P
E
S
H
R
K
P
L
K
R
Site 29
S309
H
R
K
P
L
K
R
S
S
S
E
T
I
L
S
Site 30
S310
R
K
P
L
K
R
S
S
S
E
T
I
L
S
S
Site 31
S311
K
P
L
K
R
S
S
S
E
T
I
L
S
S
L
Site 32
T313
L
K
R
S
S
S
E
T
I
L
S
S
L
A
G
Site 33
S316
S
S
S
E
T
I
L
S
S
L
A
G
S
D
I
Site 34
S344
A
V
K
Q
R
G
I
S
L
L
H
E
V
D
T
Site 35
T351
S
L
L
H
E
V
D
T
Q
Y
S
A
L
K
V
Site 36
Y353
L
H
E
V
D
T
Q
Y
S
A
L
K
V
K
Y
Site 37
S373
K
C
Q
E
E
Q
D
S
L
S
H
K
A
V
Q
Site 38
S375
Q
E
E
Q
D
S
L
S
H
K
A
V
Q
T
S
Site 39
T390
R
A
A
A
K
D
L
T
G
V
N
A
Q
S
E
Site 40
S396
L
T
G
V
N
A
Q
S
E
P
V
A
S
G
W
Site 41
S401
A
Q
S
E
P
V
A
S
G
W
E
L
A
S
V
Site 42
S407
A
S
G
W
E
L
A
S
V
N
P
E
P
V
S
Site 43
S414
S
V
N
P
E
P
V
S
S
P
T
T
P
P
E
Site 44
S415
V
N
P
E
P
V
S
S
P
T
T
P
P
E
Y
Site 45
T417
P
E
P
V
S
S
P
T
T
P
P
E
Y
K
A
Site 46
T418
E
P
V
S
S
P
T
T
P
P
E
Y
K
A
L
Site 47
Y422
S
P
T
T
P
P
E
Y
K
A
L
F
K
E
I
Site 48
T445
Q
E
I
D
E
Q
R
T
K
Y
R
S
L
S
S
Site 49
Y447
I
D
E
Q
R
T
K
Y
R
S
L
S
S
H
S
Site 50
S449
E
Q
R
T
K
Y
R
S
L
S
S
H
S
_
_
Site 51
S451
R
T
K
Y
R
S
L
S
S
H
S
_
_
_
_
Site 52
S454
Y
R
S
L
S
S
H
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation