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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TFAP4
Full Name:
Transcription factor AP-4
Alias:
Activating enhancer binding protein 4; Activating enhancer-binding protein 4; AP-4; BHLHc41; TAP4
Type:
Transcription protein
Mass (Da):
38726
Number AA:
338
UniProt ID:
Q01664
International Prot ID:
IPI00009005
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003705
GO:0003713
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0006357
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y3
_
_
_
_
_
M
E
Y
F
M
V
P
T
Q
K
Site 2
T8
M
E
Y
F
M
V
P
T
Q
K
V
P
S
L
Q
Site 3
S13
V
P
T
Q
K
V
P
S
L
Q
H
F
R
K
T
Site 4
T20
S
L
Q
H
F
R
K
T
E
K
E
V
I
G
G
Site 5
T37
S
L
A
N
I
P
L
T
P
E
T
Q
R
D
Q
Site 6
T40
N
I
P
L
T
P
E
T
Q
R
D
Q
E
R
R
Site 7
S55
I
R
R
E
I
A
N
S
N
E
R
R
R
M
Q
Site 8
S63
N
E
R
R
R
M
Q
S
I
N
A
G
F
Q
S
Site 9
T73
A
G
F
Q
S
L
K
T
L
I
P
H
T
D
G
Site 10
T78
L
K
T
L
I
P
H
T
D
G
E
K
L
S
K
Site 11
S84
H
T
D
G
E
K
L
S
K
A
A
I
L
Q
Q
Site 12
S98
Q
T
A
E
Y
I
F
S
L
E
Q
E
K
T
R
Site 13
T104
F
S
L
E
Q
E
K
T
R
L
L
Q
Q
N
T
Site 14
S121
K
R
F
I
Q
E
L
S
G
S
S
P
K
R
R
Site 15
S123
F
I
Q
E
L
S
G
S
S
P
K
R
R
R
A
Site 16
S124
I
Q
E
L
S
G
S
S
P
K
R
R
R
A
E
Site 17
S139
D
K
D
E
G
I
G
S
P
D
I
W
E
D
E
Site 18
S167
Q
Q
L
D
K
E
R
S
V
R
M
M
L
E
E
Site 19
S178
M
L
E
E
Q
V
R
S
L
E
A
H
M
Y
P
Site 20
Y184
R
S
L
E
A
H
M
Y
P
E
K
L
K
V
I
Site 21
T234
P
A
P
T
H
H
P
T
V
I
V
P
A
P
P
Site 22
S245
P
A
P
P
P
P
P
S
H
H
I
N
V
V
T
Site 23
S261
G
P
S
S
V
I
N
S
V
S
T
S
R
Q
N
Site 24
S263
S
S
V
I
N
S
V
S
T
S
R
Q
N
L
D
Site 25
S265
V
I
N
S
V
S
T
S
R
Q
N
L
D
T
I
Site 26
T271
T
S
R
Q
N
L
D
T
I
V
Q
A
I
Q
H
Site 27
T282
A
I
Q
H
I
E
G
T
Q
E
K
Q
E
L
E
Site 28
S310
S
C
P
E
A
P
T
S
D
T
A
S
D
S
E
Site 29
T312
P
E
A
P
T
S
D
T
A
S
D
S
E
A
S
Site 30
S314
A
P
T
S
D
T
A
S
D
S
E
A
S
D
S
Site 31
S316
T
S
D
T
A
S
D
S
E
A
S
D
S
D
A
Site 32
S321
S
D
S
E
A
S
D
S
D
A
M
D
Q
S
R
Site 33
S327
D
S
D
A
M
D
Q
S
R
E
E
P
S
G
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation