PhosphoNET

           
Protein Info 
   
Short Name:  PURA
Full Name:  Transcriptional activator protein Pur-alpha
Alias:  PUR1; PURALPHA; PUR-ALPHA; Purine-rich element binding protein A; Purine-rich single-stranded DNA-binding protein alpha; Transcriptional activator protein Pur-alpha: Purine-rich single-stranded DNA-binding protein alpha; Transcriptional activator Pur-alpha
Type:  DNA binding protein
Mass (Da):  34911
Number AA:  322
UniProt ID:  Q00577
International Prot ID:  IPI00023591
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005662  GO:0000784   Uniprot OncoNet
Molecular Function:  GO:0003705  GO:0003691  GO:0003697 PhosphoSite+ KinaseNET
Biological Process:  GO:0006270  GO:0006268  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MADRDSGSEQGGA
Site 2S8MADRDSGSEQGGAAL
Site 3S17QGGAALGSGGSLGHP
Site 4S20AALGSGGSLGHPGSG
Site 5S26GSLGHPGSGSGSGGG
Site 6S28LGHPGSGSGSGGGGG
Site 7S30HPGSGSGSGGGGGGG
Site 8S43GGGGGGGSGGGGGGA
Site 9T58PGGLQHETQELASKR
Site 10S63HETQELASKRVDIQN
Site 11Y74DIQNKRFYLDVKQNA
Site 12S98VGAGGNKSRLTLSMS
Site 13Y121LGDFIEHYAQLGPSQ
Site 14S127HYAQLGPSQPPDLAQ
Site 15S145EPRRALKSEFLVREN
Site 16Y155LVRENRKYYMDLKEN
Site 17Y156VRENRKYYMDLKENQ
Site 18T173RFLRIRQTVNRGPGL
Site 19S182NRGPGLGSTQGQTIA
Site 20T183RGPGLGSTQGQTIAL
Site 21Y209LAKLIDDYGVEEEPA
Site 22S223AELPEGTSLTVDNKR
Site 23T225LPEGTSLTVDNKRFF
Site 24Y240FDVGSNKYGVFMRVS
Site 25S247YGVFMRVSEVKPTYR
Site 26T252RVSEVKPTYRNSITV
Site 27Y253VSEVKPTYRNSITVP
Site 28S256VKPTYRNSITVPYKV
Site 29T258PTYRNSITVPYKVWA
Site 30Y261RNSITVPYKVWAKFG
Site 31T270VWAKFGHTFCKYSEE
Site 32Y274FGHTFCKYSEEMKKI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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