PhosphoNET

           
Protein Info 
   
Short Name:  TF2B
Full Name:  Transcription initiation factor IIB
Alias:  general transcription factor IIB; General transcription factor TFIIB; GTF2B; S300-II; TFIIB
Type: 
Mass (Da):  34830
Number AA:  316
UniProt ID:  Q00403
International Prot ID:  IPI00022820
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005654     Uniprot OncoNet
Molecular Function:  GO:0016251  GO:0005515  GO:0003743 PhosphoSite+ KinaseNET
Biological Process:  GO:0006368  GO:0044419  GO:0006355 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S5___MASTSRLDALPR
Site 2T14LDALPRVTCPNHPDA
Site 3S50DRVIDVGSEWRTFSN
Site 4T54DVGSEWRTFSNDKAT
Site 5S56GSEWRTFSNDKATKD
Site 6T61TFSNDKATKDPSRVG
Site 7S65DKATKDPSRVGDSQN
Site 8S70DPSRVGDSQNPLLSD
Site 9S76DSQNPLLSDGDLSTM
Site 10T82LSDGDLSTMIGKGTG
Site 11S92GKGTGAASFDEFGNS
Site 12Y101DEFGNSKYQNRRTMS
Site 13T106SKYQNRRTMSSSDRA
Site 14S108YQNRRTMSSSDRAMM
Site 15S109QNRRTMSSSDRAMMN
Site 16S110NRRTMSSSDRAMMNA
Site 17T123NAFKEITTMADRINL
Site 18T138PRNIVDRTNNLFKQV
Site 19Y146NNLFKQVYEQKSLKG
Site 20S150KQVYEQKSLKGRAND
Site 21T176RQEGVPRTFKEICAV
Site 22T210ETSVDLITTGDFMSR
Site 23S262AAAIYMASQASAEKR
Site 24T270QASAEKRTQKEIGDI
Site 25T284IAGVADVTIRQSYRL
Site 26S288ADVTIRQSYRLIYPR
Site 27Y289DVTIRQSYRLIYPRA
Site 28Y293RQSYRLIYPRAPDLF
Site 29T308PTDFKFDTPVDKLPQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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