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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LACTB
Full Name:
Serine beta-lactamase-like protein LACTB, mitochondrial
Alias:
FLJ14902; G24; Lactamase, beta; Mitochondrial 39S ribosomal protein L56; MRPL56; Serine beta-lactamase-like protein LACTB
Type:
Protease; Mitochondrial; EC 3.4.-.-
Mass (Da):
60694
Number AA:
547
UniProt ID:
P83111
International Prot ID:
IPI00294186
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0016787
GO:0008800
GO:0016787
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
Y
R
L
M
S
A
V
T
A
R
A
A
Site 2
S20
A
A
P
G
G
L
A
S
S
C
G
R
R
G
V
Site 3
S21
A
P
G
G
L
A
S
S
C
G
R
R
G
V
H
Site 4
S68
R
G
A
A
P
A
Q
S
P
A
A
P
D
P
E
Site 5
S77
A
A
P
D
P
E
A
S
P
L
A
E
P
P
Q
Site 6
S87
A
E
P
P
Q
E
Q
S
L
A
P
W
S
P
Q
Site 7
S92
E
Q
S
L
A
P
W
S
P
Q
T
P
A
P
P
Site 8
T95
L
A
P
W
S
P
Q
T
P
A
P
P
C
S
R
Site 9
S101
Q
T
P
A
P
P
C
S
R
C
F
A
R
A
I
Site 10
S110
C
F
A
R
A
I
E
S
S
R
D
L
L
H
R
Site 11
S111
F
A
R
A
I
E
S
S
R
D
L
L
H
R
I
Site 12
Y145
V
W
S
E
G
L
G
Y
A
D
V
E
N
R
V
Site 13
S164
E
T
V
M
R
I
A
S
I
S
K
S
L
T
M
Site 14
Y192
L
D
I
P
V
Q
H
Y
V
P
E
F
P
E
K
Site 15
S207
E
Y
E
G
E
K
V
S
V
T
T
R
L
L
I
Site 16
T209
E
G
E
K
V
S
V
T
T
R
L
L
I
S
H
Site 17
S215
V
T
T
R
L
L
I
S
H
L
S
G
I
R
H
Site 18
S218
R
L
L
I
S
H
L
S
G
I
R
H
Y
E
K
Site 19
Y223
H
L
S
G
I
R
H
Y
E
K
D
I
K
K
V
Site 20
Y236
K
V
K
E
E
K
A
Y
K
A
L
K
M
M
K
Site 21
S256
E
Q
E
K
E
G
K
S
N
E
K
N
D
F
T
Site 22
T263
S
N
E
K
N
D
F
T
K
F
K
T
E
Q
E
Site 23
S278
N
E
A
K
C
R
N
S
K
P
G
K
K
K
N
Site 24
Y293
D
F
E
Q
G
E
L
Y
L
R
E
K
F
E
N
Site 25
S301
L
R
E
K
F
E
N
S
I
E
S
L
R
L
F
Site 26
S304
K
F
E
N
S
I
E
S
L
R
L
F
K
N
D
Site 27
Y323
K
P
G
S
Q
F
L
Y
S
T
F
G
Y
T
L
Site 28
S339
A
A
I
V
E
R
A
S
G
C
K
Y
L
D
Y
Site 29
Y343
E
R
A
S
G
C
K
Y
L
D
Y
M
Q
K
I
Site 30
Y346
S
G
C
K
Y
L
D
Y
M
Q
K
I
F
H
D
Site 31
T358
F
H
D
L
D
M
L
T
T
V
Q
E
E
N
E
Site 32
T359
H
D
L
D
M
L
T
T
V
Q
E
E
N
E
P
Site 33
Y369
E
E
N
E
P
V
I
Y
N
R
A
R
F
Y
V
Site 34
Y375
I
Y
N
R
A
R
F
Y
V
Y
N
K
K
K
R
Site 35
Y377
N
R
A
R
F
Y
V
Y
N
K
K
K
R
L
V
Site 36
T386
K
K
K
R
L
V
N
T
P
Y
V
D
N
S
Y
Site 37
Y388
K
R
L
V
N
T
P
Y
V
D
N
S
Y
K
W
Site 38
Y393
T
P
Y
V
D
N
S
Y
K
W
A
G
G
G
F
Site 39
Y418
G
N
A
M
L
Y
G
Y
Q
V
G
L
F
K
N
Site 40
S426
Q
V
G
L
F
K
N
S
N
E
N
L
L
P
G
Site 41
Y434
N
E
N
L
L
P
G
Y
L
K
P
E
T
M
V
Site 42
S453
P
V
P
N
T
E
M
S
W
D
K
E
G
K
Y
Site 43
Y460
S
W
D
K
E
G
K
Y
A
M
A
W
G
V
V
Site 44
T472
G
V
V
E
R
K
Q
T
Y
G
S
C
R
K
Q
Site 45
Y473
V
V
E
R
K
Q
T
Y
G
S
C
R
K
Q
R
Site 46
S475
E
R
K
Q
T
Y
G
S
C
R
K
Q
R
H
Y
Site 47
Y482
S
C
R
K
Q
R
H
Y
A
S
H
T
G
G
A
Site 48
S484
R
K
Q
R
H
Y
A
S
H
T
G
G
A
V
G
Site 49
T505
V
L
P
E
E
L
D
T
E
T
I
N
N
K
V
Site 50
T507
P
E
E
L
D
T
E
T
I
N
N
K
V
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation