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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Kir4.1
Full Name:
ATP-sensitive inward rectifier potassium channel 10
Alias:
ATP-dependent inwardly rectifying potassium channel Kir4.1; Inward rectifier K(+) channel Kir1.2; Potassium channel, inwardly rectifying subfamily J member 10
Type:
Membrane, Integral plasma membrane protein
Mass (Da):
42508
Number AA:
379
UniProt ID:
P78508
International Prot ID:
IPI00020273
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0015272
GO:0030955
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
T
S
V
A
K
V
Y
Y
S
Q
T
T
Q
T
Site 2
Y9
T
S
V
A
K
V
Y
Y
S
Q
T
T
Q
T
E
Site 3
S10
S
V
A
K
V
Y
Y
S
Q
T
T
Q
T
E
S
Site 4
S17
S
Q
T
T
Q
T
E
S
R
P
L
M
G
P
G
Site 5
T32
I
R
R
R
R
V
L
T
K
D
G
R
S
N
V
Site 6
S37
V
L
T
K
D
G
R
S
N
V
R
M
E
H
I
Site 7
Y51
I
A
D
K
R
F
L
Y
L
K
D
L
W
T
T
Site 8
T106
L
D
P
P
A
N
H
T
P
C
V
V
Q
V
H
Site 9
T128
F
S
L
E
S
Q
T
T
I
G
Y
G
F
R
Y
Site 10
Y135
T
I
G
Y
G
F
R
Y
I
S
E
E
C
P
L
Site 11
T178
R
P
K
K
R
A
E
T
I
R
F
S
Q
H
A
Site 12
S182
R
A
E
T
I
R
F
S
Q
H
A
V
V
A
S
Site 13
S189
S
Q
H
A
V
V
A
S
H
N
G
K
P
C
L
Site 14
T237
R
L
N
Q
V
N
V
T
F
Q
V
D
T
A
S
Site 15
T242
N
V
T
F
Q
V
D
T
A
S
D
S
P
F
L
Site 16
S263
Y
H
V
V
D
E
T
S
P
L
K
D
L
P
L
Site 17
S272
L
K
D
L
P
L
R
S
G
E
G
D
F
E
L
Site 18
T293
T
V
E
S
T
S
A
T
C
Q
V
R
T
S
Y
Site 19
S299
A
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
Site 20
Y300
T
C
Q
V
R
T
S
Y
L
P
E
E
I
L
W
Site 21
S316
Y
E
F
T
P
A
I
S
L
S
A
S
G
K
Y
Site 22
Y323
S
L
S
A
S
G
K
Y
I
A
D
F
S
L
F
Site 23
S338
D
Q
V
V
K
V
A
S
P
S
G
L
R
D
S
Site 24
S345
S
P
S
G
L
R
D
S
T
V
R
Y
G
D
P
Site 25
T346
P
S
G
L
R
D
S
T
V
R
Y
G
D
P
E
Site 26
Y349
L
R
D
S
T
V
R
Y
G
D
P
E
K
L
K
Site 27
S360
E
K
L
K
L
E
E
S
L
R
E
Q
A
E
K
Site 28
S373
E
K
E
G
S
A
L
S
V
R
I
S
N
V
_
Site 29
S377
S
A
L
S
V
R
I
S
N
V
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation