PhosphoNET

           
Protein Info 
   
Short Name:  PITX1
Full Name:  Pituitary homeobox 1
Alias:  BFT; Hindlimb-expressed homeobox protein backfoot; Paired-like homeodomain 1; POTX; PTX1
Type: 
Mass (Da):  34128
Number AA:  314
UniProt ID:  P78337
International Prot ID:  IPI00019182
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005730     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9DAFKGGMSLERLPEG
Site 2S46PREPLENSASESSDT
Site 3S48EPLENSASESSDTEL
Site 4S50LENSASESSDTELPE
Site 5S51ENSASESSDTELPEK
Site 6T53SASESSDTELPEKER
Site 7S70EPKGPEDSGAGGTGC
Site 8T94KKQRRQRTHFTSQQL
Site 9S98RQRTHFTSQQLQELE
Site 10T107QLQELEATFQRNRYP
Site 11Y113ATFQRNRYPDMSMRE
Site 12S117RNRYPDMSMREEIAV
Site 13Y175VQPYEDVYAAGYSYN
Site 14S188YNNWAAKSLAPAPLS
Site 15S198PAPLSTKSFTFFNSM
Site 16T200PLSTKSFTFFNSMSP
Site 17S204KSFTFFNSMSPLSSQ
Site 18S206FTFFNSMSPLSSQSM
Site 19S209FNSMSPLSSQSMFSA
Site 20S210NSMSPLSSQSMFSAP
Site 21S212MSPLSSQSMFSAPSS
Site 22S215LSSQSMFSAPSSISS
Site 23S218QSMFSAPSSISSMTM
Site 24S221FSAPSSISSMTMPSS
Site 25S222SAPSSISSMTMPSSM
Site 26T224PSSISSMTMPSSMGP
Site 27S228SSMTMPSSMGPGAVP
Site 28S240AVPGMPNSGLNNINN
Site 29T249LNNINNLTGSSLNSA
Site 30S251NINNLTGSSLNSAMS
Site 31S252INNLTGSSLNSAMSP
Site 32S258SSLNSAMSPGACPYG
Site 33Y264MSPGACPYGTPASPY
Site 34T266PGACPYGTPASPYSV
Site 35S269CPYGTPASPYSVYRD
Site 36Y271YGTPASPYSVYRDTC
Site 37S272GTPASPYSVYRDTCN
Site 38T277PYSVYRDTCNSSLAS
Site 39S280VYRDTCNSSLASLRL
Site 40S281YRDTCNSSLASLRLK
Site 41S284TCNSSLASLRLKSKQ
Site 42S289LASLRLKSKQHSSFG
Site 43S293RLKSKQHSSFGYGGL
Site 44S294LKSKQHSSFGYGGLQ
Site 45Y297KQHSSFGYGGLQGPA
Site 46S305GGLQGPASGLNACQY
Site 47S314LNACQYNS_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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